2. • Triosephosphate
• Hexose
• Lactic acid
• Pyruvic acid
Minerals: Ion, macromolecules and
micromolecules.
Na, K, Cu, Fe, Ca, Mg and P
3. Metabolism of nervous tissue
1. Needs high amount of energy
2. Even higher in grey matter
3. Aerobic environment
4. Anabolism takes place too
5. Main substrate is glucose
6. Metabolism of amino acids
4.
5.
6.
7.
8. NEUROTRANSMITTERS
1- Most are synthesized in presynaptic terminal
2- Once synthesized, they are stored in vesicles
3- Released in response to nerve impulse:
4- Termination: by: Reuptake of the neurotransmitter into
presynaptic terminal
Or Enzymatic inactivation
12. Metabolism of Ammonia
Hyperammonia – 1. Stops Kreb’s cycle
2. Depletion of ATP
3. Accumulation of Glu
and Gln
4. Changes in osmosis
5. Influx of water