1. Rough EndoplasmicRough Endoplasmic
Reticulum (RER)Reticulum (RER)
• The RER is dotted withThe RER is dotted with
ribosomes. (Which is why it isribosomes. (Which is why it is
called “rough.”)called “rough.”)
• The RER is involved withThe RER is involved with
protein production, proteinprotein production, protein
folding, quality control andfolding, quality control and
dispatch.dispatch.
• The RER is involved with theThe RER is involved with the
synthesis of proteins. Theysynthesis of proteins. They
produce and process specificproduce and process specific
proteins at ribosomal sites.proteins at ribosomal sites.
• Consists of network-likeConsists of network-like
tunnels with tubules, vesiclestunnels with tubules, vesicles
and cisternae which is heldand cisternae which is held
together by the cytoskeleton oftogether by the cytoskeleton of
the cell.the cell.
2. Smooth Endoplasmic ReticulumSmooth Endoplasmic Reticulum
(SER)(SER)
• SME is more tubularSME is more tubular
then RER and forms athen RER and forms a
separate interconnectingseparate interconnecting
network. (Is found evenlynetwork. (Is found evenly
distributed among thedistributed among the
Cytoplasm.)Cytoplasm.)
• SME has no ribosomesSME has no ribosomes
on it.on it.