3. Presented To
Dr.Ghazala Shaheen
BEMS, Ph.D(Clinical Therapeutics)
Lecture of Clinical Therapeutics
College of Conventional Medicine
The Islamia University of Bahawalpur
5. Contents
Appendicitis
Appendix
Path physiology
Causes
Clinical Features
Diagnosis
Clinical
Blood and Urine Test
Imaging
Treatment
o Non Surgical
o Surgical
6. Appendicitis
Appendicitis is a condition in which your appendix
becomes inflamed and fills with pus.
Appendicitis is an inflammation of the appendix
Appendicitis is common. Typical symptoms
include abdominal pain and vomiting that
gradually get worse over 6-24 hours
7. What and where is the appendix?
The appendix is a small dead end pouch, like a
little tube, that comes off the caecum. The
caecum is the first part of the large intestine. Just
before the colon. The small intestine digests and
absorbs food. The parts of the food that are not
digested begin to be formed into faeces (motions)
in the caecum.
The appendix is normally about 5-10 cm long and
thin. The appendix appears to have no function.
8.
9. Path physiology of Appendicitis
Lumen Obstruction(Any hard thing,feaces,hard foof material)
Bacterial Invasion
Inflammation
Thrombosis In Appenidicular artery
Necrosis
10. Causes
The main cause of appendicitis is Obstruction of
Lumen of appendix
Cause of Lumen Blockage
Any Foreign Material
Trauma
Infection
Intestinal Worm
Lymphadenitis
Stool
11. Clinical Features
Pain in upper abdomen that becomes sharp as it moves to the lower right
abdomen.
Loss of appetite
Nausea and/or Vomiting soon after Abdominal Pain begins
Abdominal swelling
Fever of 99-102 degrees Fahrenheit
Inability to pass gas
Almost half the time, other symptoms of appendicitis appear, including:
Dull or sharp pain anywhere in the upper or lower abdomen, back, or rectum
Painful urination
Vomiting that precedes the abdominal pain
Severe cramps
Constipation or Diarrhea with gas
13. Clinical Diagnosis
Aure-Rozanova sign
Increased pain on palpation with finger in right
Lumbar Triangle
Bartomier-Michelson's sign
Increased pain on palpation at the right iliac
region as patient lies on his/her left side
compared to when patient was on supine position
Supine Position
14. Clinical Diagonsis
Dunphy's sign
Increased pain in the
right upper quadrant with coughing
Obturator sign
If an inflamed appendix is in contact with the
Obturator Internus spasm of the muscle is called
Obturator sign. It is demonstrated by flexing and
internal rotation of the hip and pain is occur in
Hypogastrium
15. Clinical Diagnosis
Sitkovskiy Sign
Increased pain in the right iliac region as patient lies
on his/her left side.
Psoas sign
If an inflamed appendix is in contact with the
Psoas major spasm of the muscle is called Psoas
Sign. It is demonstrated by flexing and internal
rotation of the right hip and pain is occur in Right
lower quadrent
16. Blood Test and Urine Test
Complete Blood Count (CBC) is done to check for
signs of infection. 70-90 percent of people with
appendicitis may have an elevated white blood
cells
Urine Analysis for Urinary Tract Infection. there is
a possibility of a microscopic Pyuria the condition
of urine containing pus, or Hematuria, urine
containing red blood cells, caused by the
proximity of the appendix to the Ureter and
bladder in acute appendicitis.
17. Imaging
X–Ray
Ultrasound
On USG free fluid collection in the right iliac fossa
is to seen
along with a visible appendix without blood flow
C.T Scane
18. Management
Non Surgical
Surgical
Antibiotics
Pre surgery
Anti-Inflammatory
After surgery
Anti-Emetic
Appendectomy
Fluid Replacement
Laparotomy
Therapy
19. Non-Surgical
Antibiotics Plants
Glycyrrhiza
Jaiphal(Myristica
Fragrens)
Dried Ripe Fruits of
Jaiphal have antibacterial activity
Cap: jaiphal 500mg
1+1+1
Joshanda-e-Istakhudos
1 packet X BD
glabra(Malathi)
Dried Roots of
Glycyrrhiza glabra is
used as a antibiotic
Cap: Pepicone 500mg
1+1
Althaea
officinalis(Khatmi)
Root, leaves and
flowers are used a
antibiotic
20. Non-Surgical
Anti-Inflammatory
Zancid
Arq-e-Makooh
It is used abdominal
cramping
by smoothing
gastrointestinal
tract,making itan
antispasmodic.
It Contain
Zinger and
Malathi
Half tea Cup X BD
Glycyrrhiza
glabra(Malathi)
Glysyrrhizin acts as
an anti-inflammatory
to inhibit the
breakdown of cortisol
and also has antibacterial properties.
Cap: Pepicone 500mg
23. Surgical Managment
Pre-Surgery
The treatment begins by keeping the patient
away from eating or drinking in preparation for
surgery
o Antibiotics
Antibiotic such as Cefotaxime Na or Ciprofloxacine
is given Intravenously
24. Surgical Treatment
Appendectomy
The Surgical procedure for the removal of the
appendix is called an Appendectomy
Laparotomy
Laparotomy is the traditional type of surgery
used for treating appendicitis. This procedure
consists in the removal of the infected appendix
through a single larger incision in the lower right
area of the abdomen.
25. Surgical Treatment
Laparoscopic surgery
The newer method to treat appendicitis is
the laproscopic Surgery This surgical procedure
consists of making three to four incisions in the
abdomen, each 0.25 to 0.5 inches (6.4 to
12.7 mm) long. This type of appendectomy is
made by inserting a special surgical tool called
laparoscope into one of the incisions. The
laparoscope is connected to a monitor outside the
patient's body and it is designed to help the
surgeon to inspect the infected area in the
abdomen. The other two incisions are made for
the specific removal of the appendix by