This document presents a study on accelerating the computation of the Pearson Correlation Coefficient, a statistical algorithm used to model functional connections between clusters of neurons in the human brain. The study designs an FPGA-based system to compute the Pearson Correlation Coefficient and compares its performance to a multi-threaded CPU and GPU implementation. Experimental results found that the FPGA solution guarantees the lowest energy consumption while the GPU achieves the best execution time. The FPGA was concluded to provide the best trade-off between performance and energy efficiency for this application.