Caco-2 cell permeability assay for drug absorption
Simon Evetts and Walter Kuehnegger
1.
2.
3.
4. • Astronaut support
- Unassigned
- Assigned
• Mission assigned
support
- Pre-mission
- In-flight
- Post-mission
ESA’s Crew Medical Support Office (Space Medicine Office)
A, B, C of Multi-disciplinary Support of Human
Spaceflight
5.
6.
7.
8. SMO Flight surgeons/nurses, Biomedical
Engineers, Exercise Specialists and more…
• Flight Surgeons and Nurses
The hostility of the space environment and the importance of the ‘human
element’ in all mission systems requires specialist human health support.
• Biomedical Engineers
• Medical projects & Technology
Team
• Consultants –
specialty experts
9.
10.
11. Russian Pingvin Suit
A useful attempt at reducing the deleterious effect
on bone/muscle.
Expedition 4 crewmembers Walz, Onufrienko and Bursch
14. From a European Space Agency Space Medicine Office
perspective;
1. Significant communication is occcurs between disciplines.
2. Easy access to subject experts is facilitated.
3. Processes and procedures are produced to act as
guidelines for the multiple disciplines to follow.
19. 19
Blue Abyss elements
Sea Space
Research
Academic
Partnership
Land & Property
Student Employment
Partnership
Academic and Industry
Collaboration
Research Arm
Facilities Blue
Abyss
Hotel
Kuehnegger
R&D Centre
22. From a Blue Abyss perspective – we will;
1. Ensure that all of the necessary skills and experiences needed
for human spaceflight related enterprise are present – people
tend to think all the answers are in own discipline!
2. Identify and provide vital hardware and services, not normally
accessible, which is deemed a necessity by involved disciplines.
3. Ensure that subject knowledgeable staff are at hand to enable
topic specific activities to be pursued.
4. Ensure that managers with multidisciplinary backgrounds are
available to coordinate multidisciplinary projects.
23. The study of human physical capabilities in
the Lunar Gravity Environment
NASA – CR – 66116 to 66119
Prof Walter
Kuehnegger
23
A, B, C of Multi-disciplinary Support of
Human Spaceflight
33. 1. Engineering principles can be applied to the human
body with effect to the centreline which immediately
provides a visual verification of human posture and its
deviation. Referred to as ‘visio-prediagnostics’.
2. Work as a team - multiple disciplines can integrate
effectively if led well and if all understand the mission
goals.
3. Every discipline sees a different path to the
achievement of a given goal. Understand where these
paths must meet to ensure the integration necessary
for success.
4. Most people simply see what they see and accept the
input as it is. But if you understand what and why you
see what you see ...then you understand its nature –
this enables you to perceive!
This depth of understanding imprints
knowledge on the mind!