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Osteoarthritis
(degenerative arthritis/hypertrophic
arthritis/osteoarthrosis)
By Muthu Rohini
Definition
● It is a non inflammatory, degenerative condition
of joints characterized by degeneration of
articular cartilage and subchonral bone and
formation of new bone ie osteophytes
● Results in deformity and ligamentous laxity
Classification
Primary OA Secondary OA
Etiology is unknown Etiology is known
Causes of secondary OA
● Trauma – intra articular #,occupational
● Developmental – CHD
● Infection – septic arthritis, brucella, tb
● Inflammation – RA, gout
● Endocrine – DM, acromegaly
● Previous joint disorders
● Obesity and excessive weight
Structure of joint cartilage
Pathology of OA
● Fibrillation
● Eburnation
● Osteophytes
● Subchondral cyst
loose flakes of the cartilage incite synovial infln
and thickening of the capsule, leading to
deformity and stiffness of joint
symptoms
● Pain is the earliest sympom
● Coarse crepitus
● Swelling
● Stiffness
● Feeling of instability
Signs
● Joint line tenderness
● Crepitus on moving joint
● Deformity
● Effusion
● Terminal limitation of joint movement
● Wasting of muscle
Radiological examination
● Narrowing of joint space
● Subchondral sclerosis
● Subchondral cyst
● Osteophyte formation
● Loose bodies
● Deformity of joint
OA knee joint
OA hip joint
Other inv
● Serological tests and ESR to ruleout
rheumatoid arthritis
● Sreum uric acid to rule out gout
● Arthroscopy, if a loosebody or freyed meniscus
is suspected
Medical management
Oral Systemic Medical Agents
- Analgesics (acetaminophen)
- NSAIDs
- Opioid analgesics
Intraarticular agents:
Hyaluronon
Glucocorticoids (effusion)
Topical agents
Supportive therapy
● Weight reduction
● Avoidance of stress and strain
● Local heat to relieve pain and stiffness
● Exercises
Surgical treatment
1-Arthroscopy: use to
Flush the joint to remove any
loose part and degenerated meniscal tears (lavage
or irrigation)
Advantage:
1-delay the need for more serious surgery
e.g. joint replacement.
2-the incision is small size.
3-the pain that result of surgery is minimal
4-restore function and decrease pain.
Disadvantage:
1-Risk of anesthesia.
2-infection
3-damage to nerve or
blood vessels
4-DVT
2-osteotomy:
Is procedure change the position or alignment of knee so your
weight shift away from the damage area.
●
eg. high tibial osteotomy for OA of knee with genu varum
intertrochanteric osteotomy for OA of hip
*Advantage:
Decrease pain and restore function.
*Disadvantage:
May need knee replacement surgery in future.
3-arthroplasty:(joint replacement)
For cases with advanced damage to joint
Advantage:
1-there are significant pain relief and improve function
Disadvantages:
1-rehabilitation may take 3to6 month.
2-the artificial joint may loosen or wear out so that second surgery is
needed.
* The life span or artificial is about 10 years in 9%of the people.
Thank you

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Osteoarthritis

  • 2. Definition ● It is a non inflammatory, degenerative condition of joints characterized by degeneration of articular cartilage and subchonral bone and formation of new bone ie osteophytes ● Results in deformity and ligamentous laxity
  • 3. Classification Primary OA Secondary OA Etiology is unknown Etiology is known
  • 4. Causes of secondary OA ● Trauma – intra articular #,occupational ● Developmental – CHD ● Infection – septic arthritis, brucella, tb ● Inflammation – RA, gout ● Endocrine – DM, acromegaly ● Previous joint disorders ● Obesity and excessive weight
  • 5. Structure of joint cartilage
  • 6. Pathology of OA ● Fibrillation ● Eburnation ● Osteophytes ● Subchondral cyst loose flakes of the cartilage incite synovial infln and thickening of the capsule, leading to deformity and stiffness of joint
  • 7. symptoms ● Pain is the earliest sympom ● Coarse crepitus ● Swelling ● Stiffness ● Feeling of instability
  • 8. Signs ● Joint line tenderness ● Crepitus on moving joint ● Deformity ● Effusion ● Terminal limitation of joint movement ● Wasting of muscle
  • 9. Radiological examination ● Narrowing of joint space ● Subchondral sclerosis ● Subchondral cyst ● Osteophyte formation ● Loose bodies ● Deformity of joint
  • 10.
  • 13. Other inv ● Serological tests and ESR to ruleout rheumatoid arthritis ● Sreum uric acid to rule out gout ● Arthroscopy, if a loosebody or freyed meniscus is suspected
  • 14. Medical management Oral Systemic Medical Agents - Analgesics (acetaminophen) - NSAIDs - Opioid analgesics Intraarticular agents: Hyaluronon Glucocorticoids (effusion) Topical agents
  • 15. Supportive therapy ● Weight reduction ● Avoidance of stress and strain ● Local heat to relieve pain and stiffness ● Exercises
  • 16. Surgical treatment 1-Arthroscopy: use to Flush the joint to remove any loose part and degenerated meniscal tears (lavage or irrigation) Advantage: 1-delay the need for more serious surgery e.g. joint replacement. 2-the incision is small size. 3-the pain that result of surgery is minimal 4-restore function and decrease pain. Disadvantage: 1-Risk of anesthesia. 2-infection 3-damage to nerve or blood vessels 4-DVT
  • 17. 2-osteotomy: Is procedure change the position or alignment of knee so your weight shift away from the damage area. ● eg. high tibial osteotomy for OA of knee with genu varum intertrochanteric osteotomy for OA of hip *Advantage: Decrease pain and restore function. *Disadvantage: May need knee replacement surgery in future.
  • 18. 3-arthroplasty:(joint replacement) For cases with advanced damage to joint Advantage: 1-there are significant pain relief and improve function Disadvantages: 1-rehabilitation may take 3to6 month. 2-the artificial joint may loosen or wear out so that second surgery is needed. * The life span or artificial is about 10 years in 9%of the people.