Emdogain is a gel containing enamel matrix proteins that has been shown to regenerate hard and soft tissues lost to periodontal disease. It works by attracting mesenchymal cells to the root surface, promoting attachment, proliferation, and differentiation which results in new cementum, bone, and periodontal ligament formation. Over 20 years of clinical studies involving over 2 million patients have demonstrated its effectiveness and safety in treating intra-bony and gingival recession defects.
2. What is Emdogain® ?
• Emdogain® is a unique, gel containing an enamel matrix
derivative of porcine origin. Long-term clinical studies have
demonstrated its effectiveness in inducing predictable
regeneration of hard and soft tissues lost to periodontal disease or
trauma.
3. Emdogain® in numbers:
• Over 20 years on the market.
• Over 2 million patients treated.*
• Over 400 clinical and 800 scientific studies.
• 10 year studies in intrabony and recession defects.
• Extremely well tolerated.
11. The concept used in a periodontal defect
Days Weeks Months One Year
The enamel matrix
protein forms a
matrix on the root
surface.
Mesenchymal
cells migrate into the
lesion, attach to the
surface and start to
proliferate.
Bone formation
starts at the
Emdogain® treated
root surface and
subsequently
new alveolar bone
will fill the defect.
A new
attachment
with cementum
and ligament is
formed along
the treated
root surface
A new functional
attachment is
achieved with time.
14. PrefGel™ (EDTA 24%*, pH 6.7)
• Effectively removes smear-layer
• Exposes the collagenous matrix of dentin surfaces
• Does not induce any detectable necrosis in the
surrounding periodontal tissues
15. Indications
• Straumann® Emdogain® can be used to support early soft tissue wound
healing in oral surgical procedures.
• Straumann® Emdogain® can be used as part of flap surgeries in general
comprising dental implantation and peri-implant procedures or as part of
soft tissue grafting and gingivectomy procedures.
• Straumann® Emdogain® used for Treatment of a self-containing defect
28. Post-surgical recommendations
• The use of Straumann® Emdogain® does not necessitate any extra
recommendations for post-surgical care other than those that are required by the
procedure itself. General recommendations and considerations related to post-
surgical care might include but are not limited to the following:
• Suture materials should be used for extended stable flap closure.
• No pressure should be applied to the flap after suturing.
• The patient should be advised not to brush in the operated area, but rinse daily
withan antiseptic mouth rinse (e.g. 0.1-0.2% chlorhexidine solution) until 3 weeks
post-surgery.
• Patients should also be instructed to avoid muscle traction or other trauma to the
operated area for the same period.
• Sutures are removed when clinical healing of the flap is stable and sutures no
longer add to wound stability.
29. Advantage of emdogain
1. promote the regeneration of cementum, alveolar
bone and periodontal ligament and to yield to
significantly higher CAL (Clinical Attachment
Level)
2. Emdogain® is also patient-friendly
3. has been demonstrated to significantly reduce
post-surgical pain and swelling,
4. improve wound healing
