Negative selection shaped bat chemosensory gene repertoires
1. Negative selection and adaptive duplication, not
sensory exchange, explain chemosensory gene
repertoires in noctilionoid bats
Liliana M. Dávalos, Elizabeth R. Dumont, Stephen Rossiter, Sharlene Santana,
Karen Sears, & Laurel R. Yohe
International Bat Research Congress, Durban
4 August 2016
2.
3. Sensory tissues are
expensive
• For neurons
• Maintaining function,
even at rest, is
energetically
expensive
• Excess functional
capacity has
increased energetic
costs
• Reduction may relate
to high energetic costs
Niven & Laughlin 2008 J. Exp. Biol.
4. Sensory exchange hypothesis
Gilad et al. 2004 PLoS Biol.
Trichromatic vision
Excess
pseudogenes
Statement 2
V. Wiebe and S.
Pääbo retract their
names from the
publication since they
are of the opinion that
the primary data do
not support the
conclusions
presented.
8. Chemosensory
trade-off?
Hayden et al. 2014 Mol. Biol. Evol.
Volume 31 • Number 10 • October 2014
Print ISSN 0737-4038
Online ISSN 1537-1719
www.mbe.oxfordjournals.org
Society for Molecular Biology and Evolution
Molecular
BBiology and
EEvolution
• A tool for inferring large Bayesian phylogenies
• Experimental models fit the data much better
• Genetic diversity in captive giant pandas
• Mosses mitochondrial genomes are frozen in time
• P450 is a genetic component for termite societies
17. Mc
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insects
blood
small verts
nectar
soft fruits
figs
Old World fruit
18. Take-home
• Lots more work
needed to get
complete inventories
• Molecular evolution
analyses show clear
patterns
• Conservation of
V1Rs
• Expansion of certain
OR subfamilies
Photo by S. Puechmaille