4. ACKNOLEDGEMENT
I TAKE THIS APPORTUNITY TO EXPRESS
MY PROFOUND GRATITUDE, DEEP
APPRICIATION AND SINCERE THANKS
FOR PROJECT SUPERVISION.
I WANT TO GIVE ALOTE OF THANX TO
Mrs. POONAM SHARMA Mam BECAUSE
WITHOUT HER GUIDENCE THIS
ZOOLOGY PROJECT HAVE NOT BEEN
COMPLETED.
5. INTRODUCTION
• Wuchereria bancriofti is parasitic
roundworm that is major cause of
lymphatic filariasis.
• It infects the lymphatic system of the
human.
• Thee are spread to human by Mosquito
vector.
• W. bancrofti is most prevalent and
affects over 120 million people of the
world.
• It also cause a chronic disease in
humans called Elephantiasis.
8. MORPHOLGY
• It is a diocious roundwarm ( sexually dimorphism).
• The adult warm, is long , cylindrical slender,and smooth with
rounded ends.
• It is white in color.
• The male warm is smalle,40 millimeters (1.6 in.) long and and 100
micrometers (0.0039 in0wide and features a ventrical curved tail.
10. LIFE CYCLE
• W. bancrofti carry out the life cycle in two
hosts.
• Human being serve as defitive host &
mosquito as their intermdiate hosts.
• First stage larvae is called microfilariae
are present in the circulation.The adult
parasite reside in lympjhatic of human
host.
• The microfileriae are mainly found in
peripheral blood and can be found at peak
amounts from 10 p.m. to 4 a.m.
• During the day they are present jn the deep
vains and during the night , they migret to
peripheral circulation host.
11.
12.
13. # The microfilarioae are transferred into the
vactor,these are mosquito species of genera Culex
, Anapheles and Aedes.
# Into the mosquitop the Microfilariaeae develope
into motile larvae called Juvenile.
# Whene the infected mosquito has its next blood
meal, W. bencrofti is egested via the mosquuit the
blood stream of new human host.
# The physiological changes likeward body temp.
oxygen tension and adernalm inactvit , and an
increased carbon dioxide tension are the sign which
shows the presence of the microfilariae in the body.
# The miocrofilarioae present inside the body
multiply itself.
14. DIAGNOSIS
• A blood smear is a simple and fairly
accuratwe diagnostic tool, provided jh blood
sample is taken during the period in the
day when the juvenuiles are in the
peripheral circulation.
• The polymerase reaction an also be
perform to detect a minute fraction as
little as 1 pg. of filarial DNA.
• Dead calcified worms can be detected by X-
RAY examination.
• Ultrascopy can also be used to detect the
movement and noises caused by th
movements of adult warms.
15.
16. TREATMENT
• The sever symptoms caused by the
parasite can be avoided by cleansing the
skin, surgery, or the use of Antihelminthic
drugs ; such as Diethylcarbamazine (DEC),
Invermectin or Albendazole.
• DEC can elmenate the adult microfilariae
from the blood.
• Albendazole is most effective in all of
them.
17. CONTROL & PRECAUTIONS
• One can use mosquito net.
• Pope may also use Insect repellents.
• There are so many physical method to prevent from
disease caused by this warms.