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DIARRHOEA
Ms. Khushboo singh
Nursing Tutor
DEFINITION
• ACC TO WHO- having three or
more loose or liquid stools per day,
or as having more stools than is
normal for that person.
INCIDENCE
• Worldwide in 2004 approximately 2.5 billion
cases of diarrhea occurred which results in
1.5 million deaths among children under the
age of five.
• This is down from a death rate of 5 million
per year two decades ago.
• Now approximately 500 million children
suffer diarrhea each year .
• Diarrhea remains the second leading cause
of death (16%) after pneumonia (17%) in
under fives
An electron micrograph of rotavirus, the cause of nearly
40% of hospitalizations from diarrhoea in children under
five
TYPES
1.On the basis of duration
Diarrhea lasts
for less than
14 days
1.Acute
diarrhea
Diarrhea lasts
for more than
14 days
2.Chronic
diarrhea
TYPES
2.On the basis of clinical
presentation
Diarrhea lasts for
several hours or
days and occurs
in condition like
cholera
1.Acute
watery
diarrhea
diarrhea
Diarrhea with
blood in stool ,
with or without
mucus is known
as dysentery
2.Acute
bloody
diarrhea
TYPES
On the basis of clinical
presentation3.On the basis of
physiology
1.Secretery
diarrhea :
means
there is an
increase in
the active
secretions
or an
inhibition of
absorption
in intestine
2.Osmotic
diarrhea :
occurs
when too
much water
is drawn in
to bowel
when child
drinks
excessive
sugar or
salt solution
3.Exudate
diarrhea :
presence of
blood and
pus in stool .
It occurs due
to
inflammatory
bowel
disease such
as ulcerative
colitis , food
poisoning ,
etc.
4.Motility-
related
diarrhea: by
the rapid
movement
of food
through the
intestine ,
This occurs
in diabetics ,
hyperthyroid
ism , etc
5.Inflammat
ory diarrhea
: occurs due
to damage to
mucosal
lining which
leads to
passive loss
of protein
rich fluid and
decrease
ability to
absorb the
lost fluid . It
can be seen
in
inflammatory
bowel
ETIOLOGY
• Bacteria : shigella , E.coli , salmonella
, staphylococcus
• Virus:influenza,adenovirus,enterovirus
,rotavirus,measles virus
• Parasites:giardia lamblia,entamoeba
histolytic and amoeba
• Fungi:candida albicans
1.Infection
• Intake of antibiotics and iron supplements2.Drugs
• Food poisoning , food allergies , over eating
and eating of stale foods
3.Dietery
cause
• Intussusception,polyps,diverticulitis,and
appendicular abscess
4.Surgical
condition
PREDISPOSING FACTOR
• More frequent in children under the age
of 2 years , with peak incidence during
6-9 months of age
1.Age
• More common in summer and rainy
season2.season
• More common in children from poor
families , living in poor sanitary
environment
3.socio-
economic status
• Higher in artificially fed children as
compared to those who breastfed4.Dietery factor
• During tooth eruption , infants put dirty
objects and fingers in mouth , thus
causing infection and diarrhea
5.Teething
PATHOPHYSIOLOGY
Diarrhea
Loss of normal
alkaline
secretions
&fluid
Metabolic
acidosis
Inflammation and
edema of mucosal
membrane
Chronic
diarrhea
Released
organic
acids
Poor nutritional status secondary to
loss of essential nutrients
Increased bacterial
growth fermentation
Increased
carbohydrate
level in gut &
increases fluid
loss
Dehydratio
n
CLINICAL FEATURES AND ASSESSMENT
1.Mild diarrhea
• May be 2-5
loose stools
which may be
green ,
offensive ,
containing
mucus and
have milk curd
like consistency
• Volume may be
small or large
• May subside in
a day or two
2.Moderate
diarrhea
• Number of
loose stools is
10 or more
• May have fever ,
irritability ,
anorexia and
vomiting
• Mild
dehydration
3.Severe
diarrhea
• May pass too
many or even
100 loose
stools within 24
hrs.
• Severe vomiting
, marked fever ,
anorexia and
irritability
• Oral intake
becomes
impracticable
Signs of various degrees of dehydrationAsk :
Diarrhea Less than 4 loose
stools/day
4-10 loose
stools/day
More than 10 loose
stools /day
vomiting None or small
amount
same Very frequent
Thirst More than normal More than normal Unable to drink
urine Normal Small amount and
dark
No urine for 6 hrs
Look :
Condition Baby is well alert Unwell , sleepy or
irritable
Very sleepy ,
unconscious , floppy
or having fits
Tears Present Present Absent
Eyes Normal Sunken Very sunken
Mouth and tongue Wet Dry Very dry
Breathing Normal Faster than normal Very fast and deep
Feel :
Skin When pinched ,
goes back quickly
When pinched ,
goes back slowly
When pinched ,
goes back very
slowly
Diagnostic evaluation
• Number and description of stools
per day , body weight , fluid intake
, frequency of urination , etc.
1.History
• To asses degree of dehydration2.Physical
examination
• For volume, consistency, color ,
pH and presence of blood ,
mucus , leucocytes , glucose ,
ova and cysts of parasites
3.Stool examination
• Helps to identify micro-organisms
4.Stool culture
• Hematocrit , BUN , WBC , serum
sodium , serum bicarbonate ,
serum chloride
5.Blood test
MANAGEMENT
1.Replacement of fluids
2.Administration of
prescribed drugs
3.Maintenance of nutritional
status
4Prevention of diarrhea
5.Educating parents
1 . Fluid replacement
Administration of ORS:
ORS can be used to
prevent development of
dehydration . At home ORS
can be made by mixing in 1
litre water , three finger
pinch salt(3gms) and 2 table
spoons
sugar(18gms).should be
given to child after every
loose stool
Composition standard ORS recommended by WHO
Content Amount in g/L Ingredient Osmolality in
mmol/L
Sodium
chloride
3.5 Sodium 90
Potassium 20
Sodium
bicarbonate
2.5 Chloride 80
Potassium
chloride
1.5 Glucose 111
Glucose 20 Bicarbonate 30
Total osmolality
= 311
New reduced osmolality ORS recommended by
WHO
Content Amount in g/L Ingredient Osmolarity in
mmol/L
Sodium
chloride
2.6 Sodium 75
Potassium 20
Trisodium
citrate
dihydrate
2.9 Chloride 65
Potassium
chloride
1.5 Glucose 75
Glucose 13.5 Citrate 10
Total
Management of patient with diarrhea depends on the severity
of dehydration- 3 plans are followed
A . Treatment plan A:This plan for child with mild dehydration .
Mothers are educated to provide home based fluids to child
like rice water , salted lassi , lemon water , coconut water ,
soups , fruit juice , dal water ,etc. The mother should be told
to give ORS after each loose stool
Oral rehydration therapy(plan A)
Age Amount of ORS to
be given after each
stool
Amount of ORS to
be made for use at
home
Less than 24 months 50-100ml 500ml/day
2-10 years 100-200ml 1000ml/day
More than 10 years As much as child
can drink
2000ml/day
B . Treatment plan B:This plan for child with moderate
dehydration . These patients need to be treated in a
hospital . It has three components
a)rehydration therapy
b)maintenance therapy
a)Oral rehydration therapy(plan B)-during first 4 hrs
Age <4
months
4-12
months
1-2
years
2-4
years
5-14
years
15
years
Approxi
m . Wt.
in kg
<5 kg 5-8 kg 8-11 kg 11-16
kg
16-30
kg
>30 kg
ORS
(in ml)
200-400 400-600 600-800 800-
1200
1200-
2200
>2200
Measur
e
(in
glass)
1-2 2-3 3-4 4-6 6-11 12-20
If the child’s age is not known , then give ORS in dose of 75ml/kg body
weight during first 4 hrs
b)maintenance therapy : ORS should be administered in
volume equal to diarrheal losses.ORS in dose of
approximately10-20 ml/kg body weight is given after each
liquid stool
C. Treatment plan C:This plan for child with severe
dehydration .Start IV fluids immediately . The best IV fluid
solution that should be given is RL solution(5%).If RL
solution not available normal saline (0.9%) can be used
IV fluid therapy(plan C)
Age First give Then give
<12 month 30ml/kg in 1
hour(repeat if radial
pulse is still weak)
70ml/kg in 5 hours
12 months-5 years 30ml/kg in 30
minutes
70ml/kg in 2 and half
hours
ORS should be given to patient in dose of 5ml/kg body weight , if
patient can drink. Reassess the patient every 15-30 mints till a
strong radial pulse is present. If the patient does not pass urine
within this period then 10ml/kg body weight of RL or blood plasma
2.Administration of prescribed
drugs:
-Antibiotics
-Binding agents like bismuth compounds
(pectin and kaolin)
-Anti motility agents ( loperamide ,
codeine)
-Anti-secretory agents( aspirin,
chlorpromazine , etc)
3.maintain nutritional status:
-fed during acute diarrhea
- breast feeding should continue along with ORS
-in non-breast fed infants diluted cow’s or
buffalo’s milk along with semi solid foods after
correction of dehydration
-soft cooked rice with milk or curd and sugar ,
mashed banana , mashed potato should be
given to child
-avoid spicy foods
-zinc supplementation
4.Educate mothers on
prevention:
-avoid bottle feeding
- good food hygiene
-balanced diet
-clean water for drinking , cooking , etc
-proper excreta disposal
-eat freshly cooked food
-proper hand washing by children before eating
food
-never use open spaces for passing stool
-isolation
T
H
A
N
K
Y
O
U

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Diarrhoea Causes and Treatment

  • 2. DEFINITION • ACC TO WHO- having three or more loose or liquid stools per day, or as having more stools than is normal for that person.
  • 3. INCIDENCE • Worldwide in 2004 approximately 2.5 billion cases of diarrhea occurred which results in 1.5 million deaths among children under the age of five. • This is down from a death rate of 5 million per year two decades ago. • Now approximately 500 million children suffer diarrhea each year . • Diarrhea remains the second leading cause of death (16%) after pneumonia (17%) in under fives
  • 4. An electron micrograph of rotavirus, the cause of nearly 40% of hospitalizations from diarrhoea in children under five
  • 5. TYPES 1.On the basis of duration Diarrhea lasts for less than 14 days 1.Acute diarrhea Diarrhea lasts for more than 14 days 2.Chronic diarrhea
  • 6. TYPES 2.On the basis of clinical presentation Diarrhea lasts for several hours or days and occurs in condition like cholera 1.Acute watery diarrhea diarrhea Diarrhea with blood in stool , with or without mucus is known as dysentery 2.Acute bloody diarrhea
  • 7. TYPES On the basis of clinical presentation3.On the basis of physiology 1.Secretery diarrhea : means there is an increase in the active secretions or an inhibition of absorption in intestine 2.Osmotic diarrhea : occurs when too much water is drawn in to bowel when child drinks excessive sugar or salt solution 3.Exudate diarrhea : presence of blood and pus in stool . It occurs due to inflammatory bowel disease such as ulcerative colitis , food poisoning , etc. 4.Motility- related diarrhea: by the rapid movement of food through the intestine , This occurs in diabetics , hyperthyroid ism , etc 5.Inflammat ory diarrhea : occurs due to damage to mucosal lining which leads to passive loss of protein rich fluid and decrease ability to absorb the lost fluid . It can be seen in inflammatory bowel
  • 8. ETIOLOGY • Bacteria : shigella , E.coli , salmonella , staphylococcus • Virus:influenza,adenovirus,enterovirus ,rotavirus,measles virus • Parasites:giardia lamblia,entamoeba histolytic and amoeba • Fungi:candida albicans 1.Infection • Intake of antibiotics and iron supplements2.Drugs • Food poisoning , food allergies , over eating and eating of stale foods 3.Dietery cause • Intussusception,polyps,diverticulitis,and appendicular abscess 4.Surgical condition
  • 9. PREDISPOSING FACTOR • More frequent in children under the age of 2 years , with peak incidence during 6-9 months of age 1.Age • More common in summer and rainy season2.season • More common in children from poor families , living in poor sanitary environment 3.socio- economic status • Higher in artificially fed children as compared to those who breastfed4.Dietery factor • During tooth eruption , infants put dirty objects and fingers in mouth , thus causing infection and diarrhea 5.Teething
  • 10. PATHOPHYSIOLOGY Diarrhea Loss of normal alkaline secretions &fluid Metabolic acidosis Inflammation and edema of mucosal membrane Chronic diarrhea Released organic acids Poor nutritional status secondary to loss of essential nutrients Increased bacterial growth fermentation Increased carbohydrate level in gut & increases fluid loss Dehydratio n
  • 11. CLINICAL FEATURES AND ASSESSMENT 1.Mild diarrhea • May be 2-5 loose stools which may be green , offensive , containing mucus and have milk curd like consistency • Volume may be small or large • May subside in a day or two 2.Moderate diarrhea • Number of loose stools is 10 or more • May have fever , irritability , anorexia and vomiting • Mild dehydration 3.Severe diarrhea • May pass too many or even 100 loose stools within 24 hrs. • Severe vomiting , marked fever , anorexia and irritability • Oral intake becomes impracticable
  • 12. Signs of various degrees of dehydrationAsk : Diarrhea Less than 4 loose stools/day 4-10 loose stools/day More than 10 loose stools /day vomiting None or small amount same Very frequent Thirst More than normal More than normal Unable to drink urine Normal Small amount and dark No urine for 6 hrs Look : Condition Baby is well alert Unwell , sleepy or irritable Very sleepy , unconscious , floppy or having fits Tears Present Present Absent Eyes Normal Sunken Very sunken Mouth and tongue Wet Dry Very dry Breathing Normal Faster than normal Very fast and deep Feel : Skin When pinched , goes back quickly When pinched , goes back slowly When pinched , goes back very slowly
  • 13.
  • 14. Diagnostic evaluation • Number and description of stools per day , body weight , fluid intake , frequency of urination , etc. 1.History • To asses degree of dehydration2.Physical examination • For volume, consistency, color , pH and presence of blood , mucus , leucocytes , glucose , ova and cysts of parasites 3.Stool examination • Helps to identify micro-organisms 4.Stool culture • Hematocrit , BUN , WBC , serum sodium , serum bicarbonate , serum chloride 5.Blood test
  • 15. MANAGEMENT 1.Replacement of fluids 2.Administration of prescribed drugs 3.Maintenance of nutritional status 4Prevention of diarrhea 5.Educating parents
  • 16. 1 . Fluid replacement Administration of ORS: ORS can be used to prevent development of dehydration . At home ORS can be made by mixing in 1 litre water , three finger pinch salt(3gms) and 2 table spoons sugar(18gms).should be given to child after every loose stool
  • 17. Composition standard ORS recommended by WHO Content Amount in g/L Ingredient Osmolality in mmol/L Sodium chloride 3.5 Sodium 90 Potassium 20 Sodium bicarbonate 2.5 Chloride 80 Potassium chloride 1.5 Glucose 111 Glucose 20 Bicarbonate 30 Total osmolality = 311
  • 18. New reduced osmolality ORS recommended by WHO Content Amount in g/L Ingredient Osmolarity in mmol/L Sodium chloride 2.6 Sodium 75 Potassium 20 Trisodium citrate dihydrate 2.9 Chloride 65 Potassium chloride 1.5 Glucose 75 Glucose 13.5 Citrate 10 Total
  • 19. Management of patient with diarrhea depends on the severity of dehydration- 3 plans are followed A . Treatment plan A:This plan for child with mild dehydration . Mothers are educated to provide home based fluids to child like rice water , salted lassi , lemon water , coconut water , soups , fruit juice , dal water ,etc. The mother should be told to give ORS after each loose stool
  • 20. Oral rehydration therapy(plan A) Age Amount of ORS to be given after each stool Amount of ORS to be made for use at home Less than 24 months 50-100ml 500ml/day 2-10 years 100-200ml 1000ml/day More than 10 years As much as child can drink 2000ml/day
  • 21. B . Treatment plan B:This plan for child with moderate dehydration . These patients need to be treated in a hospital . It has three components a)rehydration therapy b)maintenance therapy
  • 22. a)Oral rehydration therapy(plan B)-during first 4 hrs Age <4 months 4-12 months 1-2 years 2-4 years 5-14 years 15 years Approxi m . Wt. in kg <5 kg 5-8 kg 8-11 kg 11-16 kg 16-30 kg >30 kg ORS (in ml) 200-400 400-600 600-800 800- 1200 1200- 2200 >2200 Measur e (in glass) 1-2 2-3 3-4 4-6 6-11 12-20 If the child’s age is not known , then give ORS in dose of 75ml/kg body weight during first 4 hrs
  • 23. b)maintenance therapy : ORS should be administered in volume equal to diarrheal losses.ORS in dose of approximately10-20 ml/kg body weight is given after each liquid stool
  • 24. C. Treatment plan C:This plan for child with severe dehydration .Start IV fluids immediately . The best IV fluid solution that should be given is RL solution(5%).If RL solution not available normal saline (0.9%) can be used
  • 25. IV fluid therapy(plan C) Age First give Then give <12 month 30ml/kg in 1 hour(repeat if radial pulse is still weak) 70ml/kg in 5 hours 12 months-5 years 30ml/kg in 30 minutes 70ml/kg in 2 and half hours ORS should be given to patient in dose of 5ml/kg body weight , if patient can drink. Reassess the patient every 15-30 mints till a strong radial pulse is present. If the patient does not pass urine within this period then 10ml/kg body weight of RL or blood plasma
  • 26. 2.Administration of prescribed drugs: -Antibiotics -Binding agents like bismuth compounds (pectin and kaolin) -Anti motility agents ( loperamide , codeine) -Anti-secretory agents( aspirin, chlorpromazine , etc)
  • 27. 3.maintain nutritional status: -fed during acute diarrhea - breast feeding should continue along with ORS -in non-breast fed infants diluted cow’s or buffalo’s milk along with semi solid foods after correction of dehydration -soft cooked rice with milk or curd and sugar , mashed banana , mashed potato should be given to child -avoid spicy foods -zinc supplementation
  • 28. 4.Educate mothers on prevention: -avoid bottle feeding - good food hygiene -balanced diet -clean water for drinking , cooking , etc -proper excreta disposal -eat freshly cooked food -proper hand washing by children before eating food -never use open spaces for passing stool -isolation