Ligand binding assays (LBA) are analytical procedures to quantify an analyte (macromolecule) based on its affinity for a ligand, including but not limited to antibodies, antigens, receptors, oligonucleotides and peptides. There are various types of ligand binding assays, both radioactive and non-radioactive. As such, ligand binding assays are a superset of radio binding assays, that are the conceptual inverse of radioimmunoassay (RIA). Some newer sorts are referred to as "mix-and-measure" assays because they do not require separation of sure from unbound substance binding assays are used primarily in pharmacology for varied demands. Specifically, despite the human body's endogenous receptors, hormones, and other neurotransmitters, pharmacologists utilize assays so as to form medicine that are selective or mimic, the endogenously found cellular components.
According to the latest report by IMARC Group,the global gene expression analysis marketexhibited strong growth during 2015-2020.
Gene expression analysis is extensively used across clinical, research and pharmaceutical settings to study individual genes, gene pathways or greater gene activity profiles.
India Diagnostic Labs Market, Forecast and Opportunities, 2027.pdfTechSci Research
India diagnostic labs market stood at USD12319.32 million in 2021 and is expected to grow at a CAGR of 11.65% during the forecast period. This can be attributed to increasing requirements for early disease detection and finding root causes as early as possible in order to acquire suitable therapy. Click : https://bit.ly/38Meq4i
Saudi Arabia Diagnostic Labs Market, Forecast and Opportunities, 2027_Report.pdfMarcoBrown12
Saudi Arabia Diagnostic Labs market stood at USD1546.81 million in 2021 and is expected to grow at a steady CAGR of 6.79% during the forecast period.
For more information, click here: https://www.techsciresearch.com/report/saudi-arabia-diagnostic-labs-market/7937.html
BullFrog AI is a technology enabled drug development company using machine learning to usher in a new era of precision medicine. Through its collaborations with leading research institutions, including Johns Hopkins University and J. Craig Venter Institute, BullFrog AI is at the forefront of AI-driven drug development. Using its proprietary bfLEAP™ artificial intelligence platform, BullFrog AI aims to enable the successful development of pharmaceuticals and biologics by predicting which patients will respond to therapies in development. BullFrog AI is deploying bfLEAP™ for use at several critical stages of development with the intention of streamlining data analytics in therapeutics development, decreasing the overall development costs by decreasing failure rates for new therapeutics, and impacting the lives of countless patients that may have otherwise not received the therapies they need.
Lantern Pharma is an AI company transforming the cost, pace, and timeline of oncology drug discovery and development. Our proprietary AI and machine learning (ML) platform, RADR®, leverages over 25 billion oncology-focused data points and a library of 200+ advanced ML algorithms to help solve billion-dollar, real-world problems in oncology drug development. By harnessing the power of AI and with input from world-class scientific advisors and collaborators, we have accelerated the development of our growing pipeline of therapies including eleven cancer indications and an antibody-drug conjugate (ADC) program. On average, our newly developed drug programs have been advanced from initial AI insights to first-in-human clinical trials in 2-3 years and at approximately $1.0-2.0 million per program.
BullFrog AI is a technology enabled drug development company using machine learning to usher in a new era of precision medicine. Through its collaborations with leading research institutions, including Johns Hopkins University and J. Craig Venter Institute, BullFrog AI is at the forefront of AI-driven drug development. Using its proprietary bfLEAP™ artificial intelligence platform, BullFrog AI aims to enable the successful development of pharmaceuticals and biologics by predicting which patients will respond to therapies in development. BullFrog AI is deploying bfLEAP™ for use at several critical stages of development with the intention of streamlining data analytics in therapeutics development, decreasing the overall development costs by decreasing failure rates for new therapeutics, and impacting the lives of countless patients that may have otherwise not received the therapies they need.
Brochure Aptamers market - global forecast to 2020Akash Jaiswal
The report “Aptamers Market by Type (DNA, RNA, XNA), by Application (Diagnostics, Therapeutics, R&D), by Technology (SELEX, Other Technologies), by End Users (Academic Research Institutes, Biotechnology & Pharmaceutical Companies, CRO) - Global Forecast to 2020”. The global aptamers market is expected to reach $244.93 Million by 2020 from $107.56 Million in 2015, at a CAGR of 17.89%.
According to the latest report by IMARC Group,the global gene expression analysis marketexhibited strong growth during 2015-2020.
Gene expression analysis is extensively used across clinical, research and pharmaceutical settings to study individual genes, gene pathways or greater gene activity profiles.
India Diagnostic Labs Market, Forecast and Opportunities, 2027.pdfTechSci Research
India diagnostic labs market stood at USD12319.32 million in 2021 and is expected to grow at a CAGR of 11.65% during the forecast period. This can be attributed to increasing requirements for early disease detection and finding root causes as early as possible in order to acquire suitable therapy. Click : https://bit.ly/38Meq4i
Saudi Arabia Diagnostic Labs Market, Forecast and Opportunities, 2027_Report.pdfMarcoBrown12
Saudi Arabia Diagnostic Labs market stood at USD1546.81 million in 2021 and is expected to grow at a steady CAGR of 6.79% during the forecast period.
For more information, click here: https://www.techsciresearch.com/report/saudi-arabia-diagnostic-labs-market/7937.html
BullFrog AI is a technology enabled drug development company using machine learning to usher in a new era of precision medicine. Through its collaborations with leading research institutions, including Johns Hopkins University and J. Craig Venter Institute, BullFrog AI is at the forefront of AI-driven drug development. Using its proprietary bfLEAP™ artificial intelligence platform, BullFrog AI aims to enable the successful development of pharmaceuticals and biologics by predicting which patients will respond to therapies in development. BullFrog AI is deploying bfLEAP™ for use at several critical stages of development with the intention of streamlining data analytics in therapeutics development, decreasing the overall development costs by decreasing failure rates for new therapeutics, and impacting the lives of countless patients that may have otherwise not received the therapies they need.
Lantern Pharma is an AI company transforming the cost, pace, and timeline of oncology drug discovery and development. Our proprietary AI and machine learning (ML) platform, RADR®, leverages over 25 billion oncology-focused data points and a library of 200+ advanced ML algorithms to help solve billion-dollar, real-world problems in oncology drug development. By harnessing the power of AI and with input from world-class scientific advisors and collaborators, we have accelerated the development of our growing pipeline of therapies including eleven cancer indications and an antibody-drug conjugate (ADC) program. On average, our newly developed drug programs have been advanced from initial AI insights to first-in-human clinical trials in 2-3 years and at approximately $1.0-2.0 million per program.
BullFrog AI is a technology enabled drug development company using machine learning to usher in a new era of precision medicine. Through its collaborations with leading research institutions, including Johns Hopkins University and J. Craig Venter Institute, BullFrog AI is at the forefront of AI-driven drug development. Using its proprietary bfLEAP™ artificial intelligence platform, BullFrog AI aims to enable the successful development of pharmaceuticals and biologics by predicting which patients will respond to therapies in development. BullFrog AI is deploying bfLEAP™ for use at several critical stages of development with the intention of streamlining data analytics in therapeutics development, decreasing the overall development costs by decreasing failure rates for new therapeutics, and impacting the lives of countless patients that may have otherwise not received the therapies they need.
Brochure Aptamers market - global forecast to 2020Akash Jaiswal
The report “Aptamers Market by Type (DNA, RNA, XNA), by Application (Diagnostics, Therapeutics, R&D), by Technology (SELEX, Other Technologies), by End Users (Academic Research Institutes, Biotechnology & Pharmaceutical Companies, CRO) - Global Forecast to 2020”. The global aptamers market is expected to reach $244.93 Million by 2020 from $107.56 Million in 2015, at a CAGR of 17.89%.
Biotechnology Reagents Market PPT: Growth, Outlook, Demand, Keyplayer Analysi...IMARC Group
The global biotechnology reagents market size reached US$ 78,719 Million in 2022. Looking forward, IMARC Group expects the market to reach US$ 126,677 Million by 2028, exhibiting a growth rate (CAGR) of 8.50% during 2023-2028.
More Info:- https://www.imarcgroup.com/biotechnology-reagents-market
Lantern Pharma is an AI company transforming the cost, pace, and timeline of oncology drug discovery and development. Our proprietary AI and machine learning (ML) platform, RADR®, leverages over 25 billion oncology-focused data points and a library of 200+ advanced ML algorithms to help solve billion-dollar, real-world problems in oncology drug development. By harnessing the power of AI and with input from world-class scientific advisors and collaborators, we have accelerated the development of our growing pipeline of therapies including eleven cancer indications and an antibody-drug conjugate (ADC) program. On average, our newly developed drug programs have been advanced from initial AI insights to first-in-human clinical trials in 2-3 years and at approximately $1.0-2.0 million per program.
Protein Detection & Quantification Market PPT: Demand, Trends and Business Op...IMARC Group
The global protein detection & quantification market size reached US$ 2.5 Billion in 2022. Looking forward, IMARC Group expects the market to reach US$ 4.4 Billion by 2028, exhibiting a growth rate (CAGR) of 9.2% during 2023-2028.
More Info:- https://www.imarcgroup.com/protein-detection-quantification-market
Oncology Intelligence 2014 Report (Second Updated Edition)
Report to Cover all Aspects of Cancer Drug Development Intelligence
COMPANIES * MOLECULES * INDICATIONS * TECHNOLOGIES * DEALS * FUNDING
Oncology Drug Report 2014 –World’s Largest Active Resource for Decision Making, is designed to curtail down the efforts in identifying the real picture of present cancer drug development market, by bringing more authentic data under review and eliminating the undesired information.
For Details Visit :- https://omicsx.com/reports/cancer/oncology-intelligence-report-2014/
Lantern Pharma is a clinical stage biotechnology company focused on leveraging artificial intelligence (“A.I.”), machine learning and genomic date to streamline the drug development process and to identify patients who will benefit from their targeted oncology therapies. Their portfolio of therapies consists of compounds that others have tried, but failed, to develop into an approved commercialized drug. Additionally, they develop new compounds with the assistance of their A.I. platform (RADR) and biomarker driven approach. The Company is currently developing four therapeutic programs.
Latest Report Available at Advance Market Analytics, “Cannabis testing services Market” provides pin-point analysis for changing competitive dynamics and a forward looking perspective on different factors driving or restraining industry growth.
Outsourcing in Drug Development: The Contract Research (Clinical Trial) MarketMarketResearch.com
The cost and time of developing and bringing a drug to market is over $1.3 billion and often takes as long as 15 years, if not longer. Because of this, major pharmaceutical marketers continue to outsource stages of development, and over the years Kalorama Information has observed this process. In past editions of our outsourcing market studies, we found that outsourcing moved from "should" to "must." for manufacturers. This trend has only continued in the past two years. Contract Research Organizations (CROs) and other entities can expect growing demand for their services.
The demand for new drugs remains unabated, but the cost and need to bring those drugs to market is ever-increasing and intensifying. A key cost driver is the large number of failures during the expensive clinical trial phases. Driven by pressures to reduce costs, companies are increasingly implementing outsourcing strategies to increase revenues through faster drug development. By decreasing their in-house facilities and staff, and outsourcing more of their R&D functions, pharmaceutical and biotechnology companies are reshaping the drug development services industry.
Kalorama Information's Outsourcing in Drug Development: The Contract Research (Clinical Trial) Market is the third edition of this study of the drivers for outsourcing drug development, the companies involved in this market and the opportunity for revenues.
Lantern Pharma is a clinical stage oncology-focused company who is harnessing the power of Artificial Intelligence and Genomics to develop precision cancer therapies. By leveraging RADR®, Lantern's proprietary big data engine, more effective cancer treatments can be developed and delivered to the right group of patients at a faster rate and for a fraction of the cost. RADR® identifies genetic signature patterns that underpin the identification of patients for whom Lantern's portfolio of oncology drug candidates is likely to have the greatest therapeutic effect. This is the future of precision medicine and Lantern is at the forefront of AI driven transformation that will change the lives of cancer patients.
Lantern Pharma is a clinical stage biotechnology company focused on leveraging artificial intelligence (“A.I.”), machine learning and genomic date to streamline the drug development process and to identify patients who will benefit from their targeted oncology therapies. Their portfolio of therapies consists of compounds that others have tried, but failed, to develop into an approved commercialized drug. Additionally, they develop new compounds with the assistance of their A.I. platform (RADR) and biomarker driven approach. The Company is currently developing four therapeutic programs.
Quantum genomics sa product pipeline review - 2015Ambikabasa
This report provides comprehensive information on the current therapeutic developmental pipeline of Quantum Genomics SAs, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews latest updates, and featured news and press releases, along with special features on late-stage and discontinued projects.
http://www.researchmoz.us/quantum-genomics-sa-product-pipeline-review-2015-report.html
Lantern Pharma is a clinical stage oncology-focused company who is harnessing the power of Artificial Intelligence and Genomics to develop precision cancer therapies. By leveraging RADR®, Lantern's proprietary big data engine, more effective cancer treatments can be developed and delivered to the right group of patients at a faster rate and for a fraction of the cost. RADR® identifies genetic signature patterns that underpin the identification of patients for whom Lantern's portfolio of oncology drug candidates is likely to have the greatest therapeutic effect. This is the future of precision medicine and Lantern is at the forefront of AI driven transformation that will change the lives of cancer patients.
Given the stringent regulatory requirements in the health care industry, it is important for bio-pharmal companies to develop innovative Risk Evaluation and Mitigation Strategies (REMS) plans during the commercialization of certain products to ensure an acceptable risk-to-benefit ratio.
This benchmark study published by Best Practices, LLC examines how companies develop and execute successful Risk Evaluation and Mitigation Strategies (REMS) plans for newly-approved drugs in the U.S. market. This study can help bio-pharma companies in creating successful REMS programs.
Download Full Report: http://bit.ly/2aOt5Id
Lantern Pharma is a clinical stage oncology-focused company who is harnessing the power of Artificial Intelligence and Genomics to develop precision cancer therapies. By leveraging RADR®, Lantern's proprietary big data engine, more effective cancer treatments can be developed and delivered to the right group of patients at a faster rate and for a fraction of the cost. RADR® identifies genetic signature patterns that underpin the identification of patients for whom Lantern's portfolio of oncology drug candidates is likely to have the greatest therapeutic effect. This is the future of precision medicine and Lantern is at the forefront of AI driven transformation that will change the lives of cancer patients.
The recent global industry crisis due to the outbreak of COVID-19 is expected to be one of the major challenges for the vendors of this market as the production and markets of different industries have been shut down for an ambiguous period of time. Research Analyst at AMA predicts that United States Manufacturers will contribute to the maximum growth of Global Aircraft Clocks market throughout the forecasted period.
The plastic material which is used as in various component for aircraft is known as the Aerospace Plastics. Engineering plastics with high performance are a natural fit for the industry of aerospace due to their light weight compared with the other industrial materials. A typical engineering polymer has the half density of aluminum or glass and 1/6th of the density of steel.
Biotechnology Reagents Market PPT: Growth, Outlook, Demand, Keyplayer Analysi...IMARC Group
The global biotechnology reagents market size reached US$ 78,719 Million in 2022. Looking forward, IMARC Group expects the market to reach US$ 126,677 Million by 2028, exhibiting a growth rate (CAGR) of 8.50% during 2023-2028.
More Info:- https://www.imarcgroup.com/biotechnology-reagents-market
Lantern Pharma is an AI company transforming the cost, pace, and timeline of oncology drug discovery and development. Our proprietary AI and machine learning (ML) platform, RADR®, leverages over 25 billion oncology-focused data points and a library of 200+ advanced ML algorithms to help solve billion-dollar, real-world problems in oncology drug development. By harnessing the power of AI and with input from world-class scientific advisors and collaborators, we have accelerated the development of our growing pipeline of therapies including eleven cancer indications and an antibody-drug conjugate (ADC) program. On average, our newly developed drug programs have been advanced from initial AI insights to first-in-human clinical trials in 2-3 years and at approximately $1.0-2.0 million per program.
Protein Detection & Quantification Market PPT: Demand, Trends and Business Op...IMARC Group
The global protein detection & quantification market size reached US$ 2.5 Billion in 2022. Looking forward, IMARC Group expects the market to reach US$ 4.4 Billion by 2028, exhibiting a growth rate (CAGR) of 9.2% during 2023-2028.
More Info:- https://www.imarcgroup.com/protein-detection-quantification-market
Oncology Intelligence 2014 Report (Second Updated Edition)
Report to Cover all Aspects of Cancer Drug Development Intelligence
COMPANIES * MOLECULES * INDICATIONS * TECHNOLOGIES * DEALS * FUNDING
Oncology Drug Report 2014 –World’s Largest Active Resource for Decision Making, is designed to curtail down the efforts in identifying the real picture of present cancer drug development market, by bringing more authentic data under review and eliminating the undesired information.
For Details Visit :- https://omicsx.com/reports/cancer/oncology-intelligence-report-2014/
Lantern Pharma is a clinical stage biotechnology company focused on leveraging artificial intelligence (“A.I.”), machine learning and genomic date to streamline the drug development process and to identify patients who will benefit from their targeted oncology therapies. Their portfolio of therapies consists of compounds that others have tried, but failed, to develop into an approved commercialized drug. Additionally, they develop new compounds with the assistance of their A.I. platform (RADR) and biomarker driven approach. The Company is currently developing four therapeutic programs.
Latest Report Available at Advance Market Analytics, “Cannabis testing services Market” provides pin-point analysis for changing competitive dynamics and a forward looking perspective on different factors driving or restraining industry growth.
Outsourcing in Drug Development: The Contract Research (Clinical Trial) MarketMarketResearch.com
The cost and time of developing and bringing a drug to market is over $1.3 billion and often takes as long as 15 years, if not longer. Because of this, major pharmaceutical marketers continue to outsource stages of development, and over the years Kalorama Information has observed this process. In past editions of our outsourcing market studies, we found that outsourcing moved from "should" to "must." for manufacturers. This trend has only continued in the past two years. Contract Research Organizations (CROs) and other entities can expect growing demand for their services.
The demand for new drugs remains unabated, but the cost and need to bring those drugs to market is ever-increasing and intensifying. A key cost driver is the large number of failures during the expensive clinical trial phases. Driven by pressures to reduce costs, companies are increasingly implementing outsourcing strategies to increase revenues through faster drug development. By decreasing their in-house facilities and staff, and outsourcing more of their R&D functions, pharmaceutical and biotechnology companies are reshaping the drug development services industry.
Kalorama Information's Outsourcing in Drug Development: The Contract Research (Clinical Trial) Market is the third edition of this study of the drivers for outsourcing drug development, the companies involved in this market and the opportunity for revenues.
Lantern Pharma is a clinical stage oncology-focused company who is harnessing the power of Artificial Intelligence and Genomics to develop precision cancer therapies. By leveraging RADR®, Lantern's proprietary big data engine, more effective cancer treatments can be developed and delivered to the right group of patients at a faster rate and for a fraction of the cost. RADR® identifies genetic signature patterns that underpin the identification of patients for whom Lantern's portfolio of oncology drug candidates is likely to have the greatest therapeutic effect. This is the future of precision medicine and Lantern is at the forefront of AI driven transformation that will change the lives of cancer patients.
Lantern Pharma is a clinical stage biotechnology company focused on leveraging artificial intelligence (“A.I.”), machine learning and genomic date to streamline the drug development process and to identify patients who will benefit from their targeted oncology therapies. Their portfolio of therapies consists of compounds that others have tried, but failed, to develop into an approved commercialized drug. Additionally, they develop new compounds with the assistance of their A.I. platform (RADR) and biomarker driven approach. The Company is currently developing four therapeutic programs.
Quantum genomics sa product pipeline review - 2015Ambikabasa
This report provides comprehensive information on the current therapeutic developmental pipeline of Quantum Genomics SAs, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews latest updates, and featured news and press releases, along with special features on late-stage and discontinued projects.
http://www.researchmoz.us/quantum-genomics-sa-product-pipeline-review-2015-report.html
Lantern Pharma is a clinical stage oncology-focused company who is harnessing the power of Artificial Intelligence and Genomics to develop precision cancer therapies. By leveraging RADR®, Lantern's proprietary big data engine, more effective cancer treatments can be developed and delivered to the right group of patients at a faster rate and for a fraction of the cost. RADR® identifies genetic signature patterns that underpin the identification of patients for whom Lantern's portfolio of oncology drug candidates is likely to have the greatest therapeutic effect. This is the future of precision medicine and Lantern is at the forefront of AI driven transformation that will change the lives of cancer patients.
Given the stringent regulatory requirements in the health care industry, it is important for bio-pharmal companies to develop innovative Risk Evaluation and Mitigation Strategies (REMS) plans during the commercialization of certain products to ensure an acceptable risk-to-benefit ratio.
This benchmark study published by Best Practices, LLC examines how companies develop and execute successful Risk Evaluation and Mitigation Strategies (REMS) plans for newly-approved drugs in the U.S. market. This study can help bio-pharma companies in creating successful REMS programs.
Download Full Report: http://bit.ly/2aOt5Id
Lantern Pharma is a clinical stage oncology-focused company who is harnessing the power of Artificial Intelligence and Genomics to develop precision cancer therapies. By leveraging RADR®, Lantern's proprietary big data engine, more effective cancer treatments can be developed and delivered to the right group of patients at a faster rate and for a fraction of the cost. RADR® identifies genetic signature patterns that underpin the identification of patients for whom Lantern's portfolio of oncology drug candidates is likely to have the greatest therapeutic effect. This is the future of precision medicine and Lantern is at the forefront of AI driven transformation that will change the lives of cancer patients.
The recent global industry crisis due to the outbreak of COVID-19 is expected to be one of the major challenges for the vendors of this market as the production and markets of different industries have been shut down for an ambiguous period of time. Research Analyst at AMA predicts that United States Manufacturers will contribute to the maximum growth of Global Aircraft Clocks market throughout the forecasted period.
The plastic material which is used as in various component for aircraft is known as the Aerospace Plastics. Engineering plastics with high performance are a natural fit for the industry of aerospace due to their light weight compared with the other industrial materials. A typical engineering polymer has the half density of aluminum or glass and 1/6th of the density of steel.
The rotorcraft blade system is the combination of several rotary wings and a control system that creates the aerodynamic lift force that supports the weight of the helicopter along with thrust that counteracts the drag created by forwarding flight. Every primary rotor is mounted vertical mast over the top of the rotorcraft as opposed to the tail rotor. The pitch of the blade is typically controlled by a swashplate connected ultimately to the rotorcraft flight controls which a pilot may use. Rotorcraft are generally powered by the engine, through the transmission, to the rotating mast.
Ambulatory Surgery Center (ASC) Software can deliver deep insight into a surgery center's financial, clinical, and/or operational performance. Depending on the type of software, it can support improvements in areas including staff productivity, benchmarking efforts, cost-cutting initiatives, and patient, physician, and staff satisfaction. It can automate previously manual processes.
Proofreading and editing software is intended to thoroughly examine information and offer ideas for correcting spelling, grammatical, syntactical, and formational mistakes, as well as improving readability. It also looks for issues with plagiarism in the text. It also include refining a piece of writing's substance, organisation, language, and presentation.
The logistics options furnished for high-tech sectors are recognized as high-tech logistics. It entails transporting sensitive, fragile, and high-value commodities from quite specialised furnish amenities to outlets and closing clients. Logistics is described as the system of arranging and shifting assets from one area to the storage of the preferred destination, inclusive of equipment, food, liquids, inventories, materials, and people.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
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The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
2. SUMMARY
Ligand binding assays (LBA) are analytical procedures to quantify an analyte
(macromolecule) based on its affinity for a ligand, including but not limited to
antibodies, antigens, receptors, oligonucleotides and peptides. There are various
types of ligand binding assays, both radioactive and non-radioactive. As such,
ligand binding assays are a superset of radio binding assays, that are the
conceptual inverse of radioimmunoassay (RIA). Some newer sorts are referred to
as "mix-and-measure" assays because they do not require separation of sure from
unbound substance binding assays are used primarily in pharmacology for varied
demands. Specifically, despite the human body's endogenous receptors, hormones,
and other neurotransmitters, pharmacologists utilize assays so as to form medicine
that are selective or mimic, the endogenously found cellular components. On the
opposite hand, such techniques also are available to create receptor antagonists so
as to prevent are cascades. Such advances offer researchers with the power not
solely to quantify hormones and hormone receptors however also to contribute vital
pharmacological data in drug development and treatment plans.
3. Market Trend
Increasing adoption by the Biomedical Research
Market Drivers
Increasing need to detect the anti-drug antibodies in biological matrices
Opportunities
Increased research and development activities
Rapid development activities
Restraints
High cost of the procedures
Challenges
Lack of awareness
Lack of skilled labour
Key Target Audience
Supplier of Ligand Binding Assay, Governmental and Regulatory bodies and
End-Users
4. To evaluate and validate the market size various sources including primary and
secondary analysis is utilized. AMA Research follows regulatory standards such as
NAICS/SIC/ICB/TRCB, to have the better understanding of the market. The market
study is conducted on basis of more than 200 companies dealing in the market
regional as well as global areas with purpose to understand company’s positioning
regarding market value, volume and their market share for regional as well as global.
Further to bring relevance specific to any niche market we set and apply number of
criteria like Geographic Footprints, Regional Segments of Revenue, Operational
Centres, etc. The next step is to finalize a team (In-House + Data Agencies) who then
starts collecting C & D level executives and profiles, Industry experts, Opinion leaders
etc. and work towards appointment generation.
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5. MARKET SEGMENTS
By Type
Antigen Discovery Inc
Radioactive
Non-Radioactive
By Application
Biomedical Research
Drug Discovery
Others
By Region
South America
Asia Pacific
Europe
MEA
North America
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6. KEY COMPANIES PROFILED
Sygnature Discovery
Shanghai Medicilon Inc
Intertek Group plc
PerkinElmer Inc
Charles River
Alliance Pharma
Eurofins Discovery
Creative Biogene
IBR Inc
LGC Limited
Accelero Bioanalytics GmbH
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7. ADVANCE MARKET ANALYTICS
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