Aptamers Market to Reach $1.2B by 2020

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APTAMERS MARKET
GLOBAL FORECAST TO 2020
REPORT CODE
BT 3550
APTAMERS MARKET - GLOBAL FORECAST TO 2020
Aptamers Market, by Type (DNA, RNA, XNA), by Application (Diagnostics, Therapeutics, R&D), by Technology (SELEX,
Other Technologies), by End Users (Academic Research Institutes, Biotechnology & Pharmaceutical Companies, CRO)
REPORT OVERVIEW
1.1 OBJECTIVES OF THE STUDY
• To define, describe, and forecast the global aptamers market on the basis of
types, applications, technologies, end users, and regions
• To provide detailed information regarding major factors influencing growth of the
market (drivers, restraints, opportunities, and challenges)
• To strategically analyze market segments and subsegments with respect to
individual growth trends, future prospects, and contributions to the overall market
• To analyze opportunities in the market for stakeholders and provide details of the
competitive landscape for market leaders
• To forecast the size of the market segments with respect to four main regions,
namely, the Americas, Europe, Asia, and the Rest of the World
• To strategically profile key players and comprehensively analyze their core
competencies in terms of key market developments, joint ventures, mergers and
acquisitions, new product developments, agreements and partnerships, and
research and development activities
HEALTHCARE

1.2 MARKET DEFINITION
• Aptamers are short nucleic acid molecules organized into well-defined three-dimensional structures. Aptamers
bind to target protein, lipid, or nucleic acid molecules with a high degree of specificity. This specificity arises from
the three-dimensional structures of the molecules. Aptamers can be generated rapidly and applied for specific
detection, inhibition, and characterization of proteins. These can be used as pharmaceutical leads, detection
reagents, and functional proteomic level (with small molecules, antibodies, or other aptamers). The scope of this
market report includes DNA-, RNA-, and XNA-based aptamers that are used for research applications.
1.2.1 MARKET COVERED
• This report categorizes the aptamers market into the following segments:
• FIGURE 1 APTAMERS MARKET
•
BY APPLICATION
BY TECHNOLOGY
BY REGION
• Americas
• Asia
• Europe
• Rest of the World
APTAMERS
MARKET
• SELEX
• Other Technologies
• Diagnostics
• Research and
Development
• Therapeutics
Development
• Other Applications
BY END USER
• Academic and Government Research
Institutes
• Biotechnology and Pharmaceutical
Companies
• Contract Research Organizations
• Other End Users
• DNA-based Aptamers
• RNA-based Aptamers
• XNA-based Aptamers
BY TYPE
• Note: *Other applications primarily include biomarker discovery, food toxin detections, industrial chemical detections, and molecular recognition.
• **Other technologies primarily include Rapid Isolation of DNA Aptamers (RIDA), K-mer Analysis of Sequences (ASKAS), RNA aptamer isolation via dual cycles (RAPID), and in silico selection
method.
• ***Other end users primarily include food & beverage and chemical testing laboratories.
INTRODUCTION

1.2.2 YEARS CONSIDERED IN THE REPORT
•
2012 and 2013
HISTORICAL YEAR
2014
BASE YEAR
2015
PROJECTED YEAR
2015–2020
FORECAST PERIOD
• Note: For market estimates, the calendar year has been considered; whereas, for company profiles, the fiscal year has been considered.
1.3 CURRENCY
• THE CURRENCY USED FOR THIS REPORT IS USD ($).
• For companies reporting their revenues in USD, the revenues were picked from their annual reports
• For companies that reported their revenues in other currencies, the average annual currency conversion
rate was used for that particular year to convert values to USD
1.4 STAKEHOLDERS
• Aptamers Manufacturers, Vendors, and Distributors
• Pharmaceutical and Biotechnology Companies, Academic Research Institutes, and Contract Research
Organizations (CROs)
• Associations Related to Pharmaceutical and Biotechnology Research
• Market Research and Consulting Firms
1.5 LIMITATIONS
• The scope of the report is limited to nucleic acid-based aptamers. It does not include peptide-based
aptamers.
• The scope of the report is limited to the research applications of aptamers. These applications include
research related to the development of new aptamer-based diagnostic and therapeutic products. The
scope does not include aptamers used for diagnostic and therapeutic purposes.
INTRODUCTION

2 RESEARCH METHODOLOGY
• This research study involved the use of extensive secondary sources, directories, and databases such as Hoovers,
Bloomberg Business, Factiva, and Avention, to identify and collect information useful for this technical, market-
oriented, and commercial study of the aptamers market. The primary sources are mainly industry experts from
core and related industries and preferred suppliers, manufacturers, distributors, service providers, reimbursement
providers, technology developers, alliances, and standards and certification organizations from companies and
organizations related to all segments of this industry’s value chain. In-depth interviews were conducted from
various primary respondents, including key industry participants, C-level executives of key market players, and
industry consultants, to obtain and verify the critical qualitative and quantitative information and to assess future
prospects. The following figure shows the market research methodology applied in making this report on the
aptamers market.
• FIGURE 2 RESEARCH DESIGN
•
MARKET DRIVERS:
• Strong trend of R&D investments in
biotechnology and pharmaceutical
industries
• Technological advancements
• Patent expiration of SELEX
• Low cost and high efficiency as
compared to antibodies
MARKET RESTRAINTS:
• Low market acceptance
• Dearth of trained professionals
MARKET OPPORTUNITY:
• Applications in other industries
APTAMERS MARKET DYNAMICS
INFLUENCING
FACTORS
MARKET SIZE & FORECAST, BY TYPE
ARRIVE AT THE
MARKET SIZE
AND CAGR FOR
THE APTAMERS
MARKET
IMPACT
ANALYSIS OF
MARKET
TRENDS
MARKET
TRENDS MARKET SIZE & FORECAST, BY APPLICATION
MARKET SIZE & FORECAST, BY TECHNOLOGY
MARKET SIZE & FORECAST, BY END USER
• In the secondary research process, various secondary sources were referred to identify and collect information
for this study. Secondary sources include journals, certified publications, articles from recognized authors, gold
standard and silver standard websites, directories, and databases.
• Secondary research was mainly used to obtain key information about the industry’s supply chain, the market’s
monetary chain, and the total pool of key players; market classification and segmentation according to industry
trends to the bottom-most level; geographical markets; and key developments from both market- and technology-
oriented perspectives.
• In the primary research process, various primary sources from both the supply and demand sides were interviewed
to obtain qualitative and quantitative information for this report. Primary sources from the supply side include
industry experts such as CEOs, vice presidents, marketing directors, technology and innovation directors, and
related key executives from various key companies and organizations operating in the aptamers market. Primary
sources from the demand side include principal investigators and researchers.
• After complete market engineering (which includes calculations for market statistics, market breakdown, market
size estimations, market forecasting, and data triangulation), extensive primary research was conducted to gather
INTRODUCTION

information and to verify and validate the critical numbers arrived at. Primary research was also conducted to
identify the segmentation types and key market dynamics such as drivers, restraints, and opportunities.
• In the complete market engineering process, both top-down and bottom-up approaches were extensively used
along with several data triangulation methods to perform market estimation and market forecasts for the overall
market segments and subsegments listed in this report. Extensive qualitative and quantitative analysis was
performed on the complete market engineering process to list key information/insights throughout the report.
2.1 MARKET SIZE ESTIMATION
• Both, top-down and bottom-up approaches were used to estimate and validate the size of the global market
and to estimate the size of various other dependent submarkets in the overall aptamers market. The research
methodology used to estimate the market size includes the following details:
• The entire procedure includes extensive interviews for key insights from industry leaders such as CEOs, VPs,
directors, and marketing executives. All percentage shares, splits, and breakdowns were determined by using
secondary sources and verified through primary sources. All possible parameters that affect the markets covered
in this research study have been accounted for, viewed in extensive detail, verified through primary research,
and analyzed to get the final quantitative and qualitative data. This data is consolidated and added with detailed
inputs and analysis from MarketsandMarkets and presented in this report.
• The following figures show an illustrative representation of the overall market size estimation process employed
for the purpose of this study.
• FIGURE 3 MARKET SIZE ESTIMATION METHODOLOGY: BOTTOM-UP APPROACH
•
Aptamers
Market
Total Players’ Revenues in the Aptamers
Market
PRIMARY SOURCES:
Demand and Supply Side Experts
SECONDARY SOURCES:
Journals, Paid Databases,
MarketsandMarkets Repository,
Company Websites, and News
Articles
•
INTRODUCTION

• FIGURE 4 MARKET SIZE ESTIMATION METHODOLOGY:TOP-DOWN APPROACH
•
Aptamers Market
Percentage Splits for the Segments of
the Aptamers Market
Regional Split
Regional
Markets for
Each
Subsegment
Global Market Size is Validated Through
Primaries (Demand and Supply Side Experts)
PRIMARY SOURCES:
Demand and Supply Side Experts
SECONDARY SOURCES:
Journals, Paid Databases,
MarketsandMarkets Repository,
Company Websites, and News Articles
• The bottom-up procedure was employed to arrive at the overall market size of the aptamers market from the
revenue of the key players (companies). Calculations based on the revenue of key players identified in the market
led to the overall market size. This overall market size was used in the top-down procedure to estimate the
sizes of other individual markets segments through a percentage split from secondary and primary research.
For the calculation of each type of specific market segment, the most appropriate, immediate parent market size
was used for implementing the top-down procedure. The bottom-up procedure was also implemented for data
extracted from secondary research to validate the market segment revenues obtained. With the data triangulation
procedure and validation of data through primaries, the exact values of the overall parent market size and each
individual market size were determined and confirmed in this study. The data triangulation procedure implemented
for this study is explained in the next section.
• FIGURE 5 BREAKDOWN OF PRIMARY INTERVIEWS: BY DESIGNATION AND REGION
• NUMBER OF PRIMARIES: BY DESIGNATION NUMBER OF PRIMARIES: BY REGION
60.0%
40.0%
C level Others*
70.0%
30.0%
North America Europe
• Note: *Others include sales managers and marketing managers
INTRODUCTION

2.2 MARKET BREAKDOWN AND DATA TRIANGULATION
• After arriving at the overall market size from the market size estimation process explained above, the total
market was split into several segments and subsegments. In order to complete the overall market engineering
process and to arrive at the exact statistics for all segments and subsegments, the data triangulation and market
breakdown procedure was employed wherever applicable. The data was triangulated by studying various factors
and trends from both the demand and supply sides. Along with this, the market was validated using both top-
down and bottom-up approaches.
• FIGURE 6 DATA TRIANGULATION METHODOLOGY
•
MnM KNOW* stands for ‘MarketsandMarkets Knowledge Asset Management' framework. In this context, it stands for the existing
market research knowledge repository of over 5,000 granular markets, our flagship competitive intelligence and market research
platform "RT", subject-matter experts, and independent consultants. MnM KNOW acts as an independent source that helps us
validate information gathered from primary and secondary sources.
SECONDARY SOURCES
Websites, News Articles, Journals,
and Paid Databases
• International Society on Aptamers,
• National Institutes of Health (NIH)
• Scientific Publications
• World Intellectual Property
Organization
Interviews with:
• Production/Procurement/
Product Managers
• Companies/Research
Institutes
DEMANDSIDE
Interviews with:
• CEOs
• Vice Presidents
• Marketing Directors
• Technology and Innovation
Directors and Related Key
Executives from Various Key
Companies and
Organizations Operating in
the Aptamers Market
SUPPLYSIDE
INFORMATION SOURCED
Key
Players
Competitive
Landscape
Drivers and Restraints
Opportunities
Forecast
Market Size
Regional Analysis
PRIMARY SOURCES
MnM KNOW*
PRIMARY
SOURCES
SECONDARY
SOURCES
DATA
TRIANGULATION
2.2.1 KEY DATA FROM SECONDARY SOURCES
• PARAMETER SOURCES
Market Size
• Magazines
• Journals
• Paid Databases
• MarketsandMarkets Data Repository
Qualitative Information
(Market Dynamics and Trends)
• Company Websites
• MarketsandMarkets Data Repository
INTRODUCTION

2.2.2 KEY DATA FROM PRIMARY SOURCES
• DATAPARAMETERSTYPE
 Aptamers market estimates
 Historical growth rates
 Global market size for 2014
 CAGR for the forecast period
(2015–2020)
Global
Market Size
 Aptamers market, by region – Americas, Europe,
Asia, and the Rest of the World
 Overall market and subsegments
in 2014
 CAGR of each region during the
forecast period (2015–2020)
Regional
Split
 Aptamers market, by type
 Aptamers market, by application
 Aptamers market, by technology
 Aptamers market, by end user
 Percentage splits of market
segments
 Relative growth rate of each
segment
Market
Split
•
2.2.3 ASSUMPTIONS FOR THE STUDY
• PARAMETER ASSUMPTIONS
Market Growth
• CAGR for the forecast period is assumed to be
normalized and the effects of inflation, recession,
economic downturn, regulatory or policy changes, and
other factors are not considered
• The exchange rate is assumed to be same as that of
2014 for the forecast period
INTRODUCTION

1 INTRODUCTION.........................................................................................................................14
• 1.1 OBJECTIVES OF THE STUDY...........................................................................................................................................14
• 1.2 MARKET DEFINITION.......................................................................................................................................................14
• 1.2.1 MARKET COVERED........................................................................................................................................15
• 1.2.2 YEARS CONSIDERED IN THE REPORT...........................................................................................................15
• 1.3 CURRENCY......................................................................................................................................................................16
• 1.4 STAKEHOLDERS...............................................................................................................................................................16
• 1.5 LIMITATIONS....................................................................................................................................................................16
2 RESEARCH METHODOLOGY.....................................................................................................17
• 2.1 MARKET SIZE ESTIMATION.............................................................................................................................................18
• 2.2 MARKET BREAKDOWN AND DATA TRIANGULATION......................................................................................................20
• 2.2.1 KEY DATA FROM SECONDARY SOURCES.....................................................................................................21
• 2.2.2 KEY DATA FROM PRIMARY SOURCES..........................................................................................................21
• 2.2.3 ASSUMPTIONS FOR THE STUDY..................................................................................................................21
3 EXECUTIVE SUMMARY..............................................................................................................22
4 PREMIUM INSIGHTS.................................................................................................................26
• 4.1 LUCRATIVE OPPORTUNITIES IN THE GLOBAL APTAMERS MARKET..............................................................................26
• 4.2 LIFE CYCLE ANALYSIS, BY REGION (2015–2020)..........................................................................................................28
5 MARKET OVERVIEW..................................................................................................................29
• 5.1 INTRODUCTION...............................................................................................................................................................30
• 5.2 MARKET SEGMENTATION................................................................................................................................................30
• 5.2.1 BY TYPE.........................................................................................................................................................30
• 5.2.2 BY APPLICATION...........................................................................................................................................30
• 5.2.3 BY TECHNOLOGY..........................................................................................................................................31
• 5.2.4 BY END USER................................................................................................................................................31
•
TABLE OF CONTENTS

• 5.3 MARKET DYNAMICS........................................................................................................................................................32
• 5.3.1 DRIVERS........................................................................................................................................................32
• 5.3.1.1 STRONG TREND OF R&D INVESTMENTS IN BIOTECHNOLOGY
AND PHARMACEUTICAL COMPANIES.....................................................................................32
• 5.3.1.2 TECHNOLOGICAL ADVANCEMENTS........................................................................................33
• 5.3.1.3 PATENT EXPIRATION OF SELEX...............................................................................................33
• 5.3.1.4 LOW-COST AND HIGH-EFFICIENCY AS COMPARED TO ANTIBODIES....................................34
• 5.3.2 RESTRAINTS..................................................................................................................................................35
• 5.3.2.1 LOW MARKET ACCEPTANCE...................................................................................................35
• 5.3.2.2 LACK OF TRAINED PROFESSIONALS.......................................................................................36
• 5.3.3 OPPORTUNITIES............................................................................................................................................36
• 5.3.3.1 APPLICATIONS IN OTHER INDUSTRIES...................................................................................36
6 APTAMERS MARKET, BY TYPE..................................................................................................38
• 6.1 INTRODUCTION...............................................................................................................................................................39
• 6.2 DNA-BASED APTAMERS..................................................................................................................................................40
• 6.3 RNA-BASED APTAMERS..................................................................................................................................................42
• 6.4 XNA-BASED APTAMERS..................................................................................................................................................45
7 APTAMERS MARKET, BY APPLICATION....................................................................................48
• 7.1 INTRODUCTION...............................................................................................................................................................49
• 7.2 DIAGNOSTICS..................................................................................................................................................................50
• 7.3 THERAPEUTICS DEVELOPMENT.....................................................................................................................................53
• 7.4 RESEARCH AND DEVELOPMENT.....................................................................................................................................56
• 7.5 OTHER APPLICATIONS....................................................................................................................................................58
8 APTAMERS MARKET, BY TECHNOLOGY....................................................................................60
• 8.1 INTRODUCTION...............................................................................................................................................................61
• 8.2 SELEX...............................................................................................................................................................................62
• 8.3 OTHER TECHNOLOGIES...................................................................................................................................................64
TABLE OF CONTENTS

9 APTAMERS MARKET, BY END USER.........................................................................................67
• 9.1 INTRODUCTION...............................................................................................................................................................68
• 9.2 ACADEMIC AND GOVERNMENT RESEARCH INSTITUTES..............................................................................................69
• 9.3 BIOTECHNOLOGY AND PHARMACEUTICAL COMPANIES..............................................................................................71
• 9.4 CONTRACT RESEARCH ORGANIZATIONS.......................................................................................................................73
• 9.5 OTHER END USERS..........................................................................................................................................................75
10 GLOBAL APTAMERS MARKET, BY REGION...............................................................................77
• 10.1 INTRODUCTION...............................................................................................................................................................78
• 10.2 AMERICAS.......................................................................................................................................................................80
• 10.2.1 U.S.................................................................................................................................................................87
• 10.2.2 CANADA.........................................................................................................................................................89
• 10.2.3 LATIN AMERICA.............................................................................................................................................90
• 10.3 EUROPE............................................................................................................................................................................93
• 10.4 ASIA.................................................................................................................................................................................99
• 10.5 REST OF THE WORLD (ROW).........................................................................................................................................103
11 COMPETITIVE LANDSCAPE.....................................................................................................107
• 11.1 INTRODUCTION.............................................................................................................................................................107
• 11.2 COMPETITIVE SITUATION AND TRENDS.......................................................................................................................107
• 11.2.1 AGREEMENTS, COLLABORATIONS, EXPANSIONS, AND PARTNERSHIPS..................................................108
• 11.2.2 CONTRACTS, DEVELOPMENT AGREEMENTS, FUNDING, GRANTS, AND REWARDS.................................109
• 11.2.3 NEW PRODUCT LAUNCHES........................................................................................................................109
• 11.2.4 OTHER DEVELOPMENTS.............................................................................................................................110
TABLE OF CONTENTS

12 COMPANY PROFILES...............................................................................................................111
• (Company at a Glance, Recent Financials, Products & Services, Strategies & Insights, & Recent Developments)*
• 12.1 AM BIOTECHNOLOGIES, LLC........................................................................................................................................111
• 12.2 APTAGEN, LLC...............................................................................................................................................................113
• 12.3 APTAMER SCIENCES INC..............................................................................................................................................114
• 12.4 APTAMER SOLUTIONS LTD...........................................................................................................................................116
• 12.5 APTUS BIOTECH S.L......................................................................................................................................................117
• 12.6 BASE PAIR BIOTECHNOLOGIES, INC.............................................................................................................................119
• 12.7 NEOVENTURES BIOTECHNOLOGY INC.........................................................................................................................121
• 12.8 SOMALOGIC, INC..........................................................................................................................................................122
• 12.9 TRILINK BIOTECHNOLOGIES, INC.................................................................................................................................124
• 12.10 VIVONICS, INC...............................................................................................................................................................125
• *Details on company at a glance, recent financials, products & services, strategies & insights, & recent developments might not be captured in case of unlisted companies.
13 APPENDIX................................................................................................................................126
• 13.1 INSIGHTS OF INDUSTRY EXPERTS...............................................................................................................................126
• 13.2 DISCUSSION GUIDE......................................................................................................................................................127
• 13.3 INTRODUCING RT: REAL-TIME MARKET INTELLIGENCE..............................................................................................129
• 13.4 AVAILABLE CUSTOMIZATIONS......................................................................................................................................130
• 13.5 RELATED REPORTS........................................................................................................................................................131
•
TABLE OF CONTENTS

• TABLE 1 APTAMERS MARKET SUMMARY.......................................................................................................................22
• TABLE 2 INCREASING R&D INVESTMENTS BY BIOTECHNOLOGY AND
PHARMACEUTICAL COMPANIES IS PROPELLING THE GROWTH OF THE APTAMERS MARKET.....................34
• TABLE 3 LOW MARKET ACCEPTANCE OF APTAMERS AS COMPARED TO
ANTIBODIES WOULD RESTRICT THE MARKET GROWTH.................................................................................36
• TABLE 4 APPLICATIONS IN OTHER INDUSTRIES PRESENT SIGNIFICANT
GROWTH OPPORTUNITIES FOR THE APTAMERS MARKET..............................................................................37
• TABLE 5 APTAMERS MARKET SIZE, BY TYPE, 2013–2020 ($MILLION).........................................................................39
• TABLE 6 DNA-BASED APTAMERS GENERATED AGAINST VARIOUS LIGANDS...............................................................40
• TABLE 7 DNA-BASED APTAMERS MARKET SIZE, BY REGION, 2013–2020 ($MILLION)................................................41
• TABLE 8 AMERICAS: DNA-BASED APTAMERS MARKET SIZE, BY COUNTRY, 2013–2020 ($MILLION).........................42
• TABLE 9 RNA-BASED APTAMERS GENERATED AGAINST VARIOUS LIGANDS...............................................................43
• TABLE 10 RNA-BASED APTAMERS MARKET SIZE, BY REGION, 2013–2020 ($MILLION)................................................44
• TABLE 11 AMERICAS: RNA-BASED APTAMERS MARKET SIZE, BY COUNTRY, 2013–2020 ($MILLION).........................45
• TABLE 12 COMMON CHEMICAL MODIFICATIONS OF APTAMERS FOR TUMOR TARGETING..........................................46
• TABLE 13 XNA-BASED APTAMERS MARKET SIZE, BY REGION, 2013–2020 ($MILLION)................................................47
• TABLE 14 AMERICAS: XNA-BASED APTAMERS MARKET SIZE, BY COUNTRY, 2013–2020 ($MILLION).........................47
• TABLE 15 APTAMERS MARKET SIZE, BY APPLICATION, 2013–2020 ($MILLION)............................................................50
• TABLE 16 LIST OF RNA APTAMER SEQUENCES AND THEIR TARGETS FOR
TARGETED THERAPY AND THEIR DIAGNOSTIC APPLICATIONS.......................................................................51
• TABLE 17 APTAMERS MARKET SIZE FOR DIAGNOSTICS APPLICATION, BY REGION, 2013–2020 ($MILLION)..............52
• TABLE 18 THE AMERICAS: APTAMERS MARKET SIZE FOR DIAGNOSTICS, BY REGION, 2013–2020 ($MILLION)..........53
• TABLE 19 STATUS OF APTAMER THERAPEUTICS UNDERGOING CLINICAL TRAILS........................................................54
• TABLE 20 APTAMERS MARKET SIZE FOR THERAPEUTICS DEVELOPMENT APPLICATION,
BY REGION, 2013–2020 ($MILLION).................................................................................................................55
• TABLE 21 AMERICAS: APTAMERS MARKET SIZE FOR THERAPEUTICS DEVELOPMENT,
• TABLE 22 APTAMERS MARKET SIZE FOR RESEARCH AND DEVELOPMENT, BY REGION, 2013–2020 ($MILLION)........57
• TABLE 23 AMERICAS: APTAMERS MARKET SIZE FOR RESEARCH AND DEVELOPMENT,
• TABLE 24 APTAMERS MARKET SIZE FOR OTHER APPLICATIONS, BY REGION,
2013–2020 ($MILLION).....................................................................................................................................59
LIST OF TABLES

• TABLE 25 AMERICAS: APTAMERS MARKET SIZE FOR OTHER APPLICATIONS,
• TABLE 26 APTAMERS MARKET SIZE, BY TECHNOLOGY, 2013–2020 ($MILLION)...........................................................61
• TABLE 27 LIST OF MODIFICATIONS TO THE SELEX PROCESS AND THEIR DESCRIPTIONS............................................62
• TABLE 28 APTAMERS MARKET SIZE FOR SELEX, BY REGION, 2013–2020 ($MILLION)..................................................63
• TABLE 29 AMERICAS: APTAMERS MARKET SIZE FOR SELEX, BY REGION,
2013–2020 ($MILLION).....................................................................................................................................64
• TABLE 30 APTAMERS MARKET SIZE FOR OTHER TECHNOLOGIES, BY REGION,
2013–2020 ($MILLION).....................................................................................................................................65
• TABLE 31 AMERICAS: APTAMERS MARKET SIZE FOR OTHER TECHNOLOGIES,
• TABLE 32 APTAMERS MARKET SIZE, BY END USER, 2013–2020 ($MILLION).................................................................69
• TABLE 33 APTAMERS MARKET SIZE FOR ACADEMIC AND GOVERNMENT
RESEARCH INSTITUTES, BY REGION, 2013–2020 ($MILLION)........................................................................70
• TABLE 34 AMERICAS: APTAMERS MARKET SIZE FOR ACADEMIC AND GOVERNMENT
RESEARCH INSTITUTES, BY COUNTRY, 2013–2020 ($MILLION).....................................................................71
• TABLE 35 APTAMERS MARKET SIZE FOR BIOTECHNOLOGY AND PHARMACEUTICAL
COMPANIES, BY REGION, 2013–2020 ($MILLION)..........................................................................................72
• TABLE 36 AMERICAS: APTAMERS MARKET SIZE FOR BIOTECHNOLOGY AND
PHARMACEUTICAL COMPANIES, BY COUNTRY, 2013–2020 ($MILLION).......................................................73
• TABLE 37 APTAMERS MARKET SIZE FOR CROS, BY REGION, 2013–2020 ($MILLION)...................................................74
• TABLE 38 AMERICAS: APTAMERS MARKET SIZE FOR CROS, BY COUNTRY,
2013–2020 ($MILLION).....................................................................................................................................74
• TABLE 39 APTAMERS MARKET SIZE FOR OTHER END USERS, BY REGION,
2013–2020 ($MILLION).....................................................................................................................................76
• TABLE 40 AMERICAS: APTAMERS MARKET SIZE FOR OTHER END USERS,
BY COUNTRY, 2013–2020 ($MILLION).............................................................................................................76
• TABLE 41 APTAMERS MARKET SIZE, BY REGION, 2013–2020 ($MILLION).....................................................................79
• TABLE 42 AMERICAS: APTAMERS MARKET SIZE, BY COUNTRY, 2013–2020 ($MILLION)..............................................82
• TABLE 43 AMERICAS: APTAMERS MARKET SIZE, BY TYPE, 2013–2020 ($MILLION)......................................................83
• TABLE 44 AMERICAS: APTAMERS MARKET SIZE, BY APPLICATION, 2013–2020 ($MILLION)........................................84
• TABLE 45 AMERICAS: APTAMERS MARKET SIZE, BY TECHNOLOGY, 2013–2020 ($MILLION).......................................85
• TABLE 46 AMERICAS: APTAMERS MARKET SIZE, BY END USER, 2013–2020 ($MILLION).............................................86
LIST OF TABLES

• TABLE 47 U.S.: APTAMERS MARKET SIZE, BY TYPE, 2013–2020 ($MILLION).................................................................87
• TABLE 48 U.S.: APTAMERS MARKET SIZE, BY APPLICATION, 2013–2020 ($MILLION)...................................................88
• TABLE 49 U.S.: APTAMERS MARKET SIZE, BY TECHNOLOGY, 2013–2020 ($MILLION)..................................................88
• TABLE 50 U.S.: APTAMERS MARKET SIZE, BY END USER, 2013–2020 ($MILLION)........................................................88
• TABLE 51 CANADA: APTAMERS MARKET SIZE, BY TYPE, 2013–2020 ($MILLION).........................................................89
• TABLE 52 CANADA: APTAMERS MARKET SIZE, BY APPLICATION, 2013–2020 ($MILLION)...........................................89
• TABLE 53 CANADA: APTAMERS MARKET SIZE, BY TECHNOLOGY, 2013–2020 ($MILLION)...........................................90
• TABLE 54 CANADA: APTAMERS MARKET SIZE, BY END USER, 2013–2020 ($MILLION).................................................90
• TABLE 55 LATIN AMERICA: APTAMERS MARKET SIZE, BY TYPE, 2013–2020 ($MILLION).............................................91
• TABLE 56 LATIN AMERICA: APTAMERS MARKET SIZE, BY APPLICATION,
2013–2020 ($MILLION).....................................................................................................................................91
• TABLE 57 LATIN AMERICA: APTAMERS MARKET SIZE, BY TECHNOLOGY,
2013–2020 ($MILLION).....................................................................................................................................92
• TABLE 58 LATIN AMERICA: APTAMERS MARKET SIZE, BY END USER, 2013–2020 ($MILLION).....................................92
• TABLE 59 EUROPE: APTAMERS MARKET SIZE, BY TYPE, 2013–2020 ($MILLION)..........................................................95
• TABLE 60 EUROPE: APTAMERS MARKET SIZE, BY APPLICATION, 2013–2020 ($MILLION)............................................96
• TABLE 61 EUROPE: APTAMERS MARKET SIZE, BY TECHNOLOGY, 2013–2020 ($MILLION)............................................97
• TABLE 62 EUROPE: APTAMERS MARKET SIZE, BY END USER, 2013–2020 ($MILLION).................................................98
• TABLE 63 ASIA: APTAMERS MARKET SIZE, BY TYPE, 2013–2020 ($MILLION)..............................................................100
• TABLE 64 ASIA: APTAMERS MARKET SIZE, BY APPLICATION, 2013–2020 ($MILLION)................................................100
• TABLE 65 ASIA: APTAMERS MARKET SIZE, BY TECHNOLOGY, 2013–2020 ($MILLION)...............................................101
• TABLE 66 ASIA: APTAMERS MARKET SIZE, BY END USER, 2013–2020 ($MILLION).....................................................102
• TABLE 67 ROW: APTAMERS MARKET SIZE, BY TYPE, 2013–2020 ($MILLION).............................................................104
• TABLE 68 ROW: APTAMERS MARKET SIZE, BY APPLICATION, 2013–2020 ($MILLION)................................................104
• TABLE 69 ROW: APTAMERS MARKET SIZE, BY TECHNOLOGY, 2013–2020 ($MILLION)...............................................105
• TABLE 70 ROW: APTAMERS MARKET SIZE, BY END USER, 2013–2020 ($MILLION).....................................................106
• TABLE 71 AGREEMENTS, COLLABORATIONS, EXPANSIONS, AND PARTNERSHIPS, 2011–2015..................................108
• TABLE 72 CONTRACTS, DEVELOPMENT AGREEMENTS, FUNDING, GRANTS, AND REWARDS, 2011–2015................109
• TABLE 73 NEW PRODUCT LAUNCHES, 2011–2015........................................................................................................110
• TABLE 74 OTHER DEVELOPMENTS, 2011–2015.............................................................................................................110
•
LIST OF TABLES

• FIGURE 1 APTAMERS MARKET..........................................................................................................................................15
• FIGURE 2 RESEARCH DESIGN...........................................................................................................................................17
• FIGURE 3 MARKET SIZE ESTIMATION METHODOLOGY: BOTTOM-UP APPROACH.........................................................18
• FIGURE 4 MARKET SIZE ESTIMATION METHODOLOGY: TOP-DOWN APPROACH...........................................................19
• FIGURE 5 BREAKDOWN OF PRIMARY INTERVIEWS: BY DESIGNATION AND REGION.....................................................19
• FIGURE 6 DATA TRIANGULATION METHODOLOGY...........................................................................................................20
• FIGURE 7 APTAMERS MARKET SIZE, BY TYPE, 2015 VS. 2020 ($MILLION)....................................................................23
• FIGURE 8 APTAMERS MARKET SIZE, BY APPLICATION, 2015 VS. 2020 ($MILLION)......................................................23
• FIGURE 9 APTAMERS MARKET SIZE, BY TECHNOLOGY, 2015 VS. 2020 ($MILLION)......................................................24
• FIGURE 10 APTAMERS MARKET SIZE, BY END USER, 2015 VS. 2020 ($MILLION)............................................................24
• FIGURE 11 APTAMERS MARKET SIZE, BY REGION, 2015 VS. 2020 ($MILLION)................................................................25
• FIGURE 12 GLOBAL APTAMERS MARKET TO WITNESS HIGH GROWTH DURING THE FORECAST PERIOD......................26
• FIGURE 13 DIAGNOSTICS APPLICATIONS TO ACCOUNT FOR THE LARGEST MARKET SHARE IN 2015...........................26
• FIGURE 14 EUROPE TO WITNESS HIGHEST GROWTH RATE FROM 2015 TO 2020............................................................27
• FIGURE 15 EUROPEAN MARKET SHOWCASES LUCRATIVE GROWTH OPPORTUNITIES...................................................28
• FIGURE 16 APTAMERS MARKET SEGMENTATION: BY TYPE..............................................................................................30
• FIGURE 17 APTAMERS MARKET SEGMENTATION: BY APPLICATION.................................................................................30
• FIGURE 18 APTAMERS MARKET SEGMENTATION: TECHNOLOGY.....................................................................................31
• FIGURE 19 APTAMERS MARKET SEGMENTATION: BY END USER......................................................................................31
• FIGURE 20 STRONG TREND OF R&D INVESTMENTS BY BIOTECHNOLOGY AND
PHARMACEUTICAL COMPANIES WILL DRIVE THE APTAMERS MARKET........................................................32
• FIGURE 21 NEW PHARMACEUTICAL DRUG LAUNCHES (2003–2013)...............................................................................33
• FIGURE 22 APTAMERS MARKET SEGMENTATION, BY TYPE..............................................................................................39
• FIGURE 23 DNA-BASED APTAMERS SEGMENT COMMAND THE LARGEST SHARE OF
THE APTAMERS MARKET, 2015 ($MILLION).....................................................................................................39
• FIGURE 24 THE AMERICAS TO COMMAND THE LARGEST SHARE OF THE
DNA-BASED APTAMERS MARKET BY 2020......................................................................................................41
• FIGURE 25 THE AMERICAS TO COMMAND THE LARGEST SHARE OF THE
RNA-BASED APTAMERS MARKET IN 2015.......................................................................................................44
• FIGURE 26 EUROPE TO BE THE LARGEST AND FASTEST-GROWING
REGIONAL SEGMENT OF THE XNA-BASED APTAMERS MARKET BY 2020......................................................46
• FIGURE 27 APTAMERS MARKET, BY APPLICATION............................................................................................................49
LIST OF FIGURES

• FIGURE 28 DIAGNOSTICS APPLICATION SEGMENT COMMANDS THE
LARGEST SHARE OF THE APTAMERS MARKET IN 2015 ($MILLION)...............................................................49
• FIGURE 29 EUROPE, THE FASTEST-GROWING REGIONAL SEGMENT
FOR DIAGNOSTICS APPLICATIONS, 2015 VS. 2020 ($MILLION).....................................................................52
• FIGURE 30 AMERICAS EXPECTED TO BE THE LARGEST REGIONAL
SEGMENT FOR THERAPEUTICS DEVELOPMENT APPLICATION ($MILLION)...................................................54
• FIGURE 31 AMERICAS TO DOMINATE THE R&D APPLICATION SEGMENT IN 2015...........................................................56
• FIGURE 32 EUROPEAN OTHER APPLICATIONS SEGMENT TO WITNESS FASTEST GROWTH............................................58
• FIGURE 33 APTAMERS MARKET SEGMENTATION, BY TECHNOLOGY................................................................................61
• FIGURE 34 APTAMERS MARKET, BY TECHNOLOGY, 2015 VS. 2020 ($MILLION)..............................................................61
• FIGURE 35 AMERICAS TO COMMAND THE LARGEST SHARE OF THE SELEX SEGMENT BY 2020...................................63
• FIGURE 36 EUROPE WILL BE THE FASTEST-GROWING REGIONAL SEGMENT
FOR OTHER TECHNOLOGIES IN 2020...............................................................................................................65
• FIGURE 37 APTAMERS MARKET SEGMENTATION, BY END USER......................................................................................68
• FIGURE 38 APTAMERS MARKET SIZE, BY END USER, 2015 VS. 2020 ($MILLION)............................................................68
• FIGURE 39 PUBLIC-SECTOR RESEARCH FUNDING IS DRIVING THE GROWTH OF
THE ACADEMIC & GOVERNMENT RESEARCH INSTITUTES MARKET..............................................................69
• FIGURE 40 THE AMERICAS DOMINATE THE APTAMERS MARKET FOR ACADEMIC
AND GOVERNMENT RESEARCH INSTITUTES...................................................................................................70
• FIGURE 41 NUMBER OF BIOTECHNOLOGY AND PHARMACEUTICAL PATENTS GRANTED IN 2012, BY REGION.............71
• FIGURE 42 BIOTECHNOLOGY AND PHARMACEUTICAL COMPANIES SEGMENT
TO WITNESS THE HIGHEST GROWTH IN EUROPE............................................................................................72
• FIGURE 43 THE AMERICAS ARE EXPECTED TO DOMINATE THE APTAMERS MARKET FOR CROS...................................74
• FIGURE 44 EUROPE TO WITNESS HIGHEST GROWTH IN THE APTAMERS
MARKET FOR OTHER END USERS IN THE FORECAST PERIOD........................................................................75
• FIGURE 45 APTAMERS MARKET SEGMENTATION, BY REGION..........................................................................................78
• FIGURE 46 AMERICAS TO DOMINATE THE GLOBAL APTAMERS MARKET.........................................................................78
• FIGURE 47 APTAMERS MARKET IN EUROPE TO WITNESS THE HIGHEST GROWTH FROM 2015 TO 2020.......................79
• FIGURE 48 AMERICAS: MARKET SNAPSHOT......................................................................................................................81
• FIGURE 49 U.S. TO DOMINATE THE APTAMERS MARKET IN THE AMERICAS...................................................................82
• FIGURE 50 DNA-BASED APTAMERS TO COMMAND THE LARGEST SHARE OF
THE APTAMERS MARKET IN THE AMERICAS...................................................................................................83
•
LIST OF FIGURES

• FIGURE 51 DIAGNOSTICS SEGMENT TO ACCOUNT FOR THE LARGEST SHARE OF THE
APTAMERS APPLICATIONS MARKET IN AMERICAS.........................................................................................84
• FIGURE 52 SELEX FORMED THE LARGEST TECHNOLOGY SEGMENT IN THE AMERICAS.................................................85
• FIGURE 53 ACADEMIC AND GOVERNMENT RESEARCH INSTITUTES FORMED THE
LARGEST END-USER SEGMENT IN THE AMERICAS.........................................................................................86
• FIGURE 54 EUROPE: MARKET SNAPSHOT..........................................................................................................................94
• FIGURE 55 DNA-BASED APTAMERS TO COMMAND THE LARGEST SHARE OF THE
EUROPEAN APTAMERS MARKET.....................................................................................................................95
• FIGURE 56 DIAGNOSTICS SEGMENT TO ACCOUNT FOR THE LARGEST SHARE OF
THE APTAMERS APPLICATIONS MARKET IN EUROPE......................................................................................96
• FIGURE 57 SELEX FORMED THE LARGEST TECHNOLOGY SEGMENT IN EUROPE............................................................97
• FIGURE 58 ACADEMIC AND GOVERNMENT RESEARCH INSTITUTES ACCOUNT
FOR THE LARGEST SHARE OF THE APTAMERS END-USERS MARKET IN EUROPE.........................................98
APTAMERS MARKET IN ASIA............................................................................................................................99
• FIGURE 60 DIAGNOSTICS APPLICATION SEGMENT TO DOMINATE THE APTAMERS MARKET
IN ASIA.............................................................................................................................................................100
• FIGURE 61 SELEX SEGMENT TO ACCOUNT FOR THE LARGEST SHARE OF THE APTAMERS
TECHNOLOGIES MARKET IN ASIA..................................................................................................................101
• FIGURE 62 ACADEMIC AND GOVERNMENT RESEARCH INSTITUTES TO ACCOUNT FOR
THE LARGEST SHARE OF THE APTAMERS END-USER MARKET IN ASIA.......................................................102
ROW APTAMERS MARKET...............................................................................................................................103
• FIGURE 64 THE DIAGNOSTICS APPLICATION SEGMENT TO COMMAND THE
LARGEST SHARE OF THE APTAMERS MARKET IN THE ROW REGION...........................................................104
• FIGURE 65 THE SELEX TECHNOLOGY SEGMENT IS EXPECTED TO DOMINATE
THE ROW APTAMERS MARKET IN 2015..........................................................................................................105
• FIGURE 66 ACADEMIC AND GOVERNMENT RESEARCH INSTITUTES SEGMENT
TO DOMINATE THE ROW MARKET FOR APTAMERS.......................................................................................106
• FIGURE 67 GROWTH STRATEGIES: AGREEMENTS, COLLABORATIONS, EXPANSIONS,
AND PARTNERSHIPS WAS THE KEY STRATEGY.............................................................................................107
LIST OF FIGURES

TABLE 1 APTAMERS MARKET SIZE, BY TYPE, 2013–2020 ($MILLION)
Type 2013 2014 2015 2020
CAGR
(2015–2020)
DNA-based Aptamers xx xx xx xx xx
RNA-based Aptamers xx xx xx xx xx
XNA-based Aptamers xx xx xx xx xx
TOTAL xx xx xx xx xx
Source: International Society on Aptamers, National Institutes of Health (NIH), Scientific Publications, World Intellectual Property Organization, Expert Interviews, and MarketsandMarkets Analysis
TABLE 2 DNA-BASED APTAMERS MARKET SIZE, BY REGION, 2013–2020 ($MILLION)
Region 2013 2014 2015 2020
CAGR
(2015–2020)
Americas xx xx xx xx xx
Europe xx xx xx xx xx
Asia xx xx xx xx xx
RoW xx xx xx xx xx
TABLE 3 AMERICAS: DNA-BASED APTAMERS MARKET SIZE,
BY COUNTRY, 2013–2020 ($MILLION)
Country/Region 2013 2014 2015 2020
CAGR
(2015–2020)
U.S. xx xx xx xx xx
Canada xx xx xx xx xx
Latin America xx xx xx xx xx
SAMPLE TABLES

RELATED REPORTS
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SR. NO. REPORT TITLE PUBLISHED DATE
1
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