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Pharmaceutical Dosages Form
Kamrul Hasan Sabbir
ID.171211001
9th batch,
Pharmacy Department
Overview
Pharmaceutical dosages form
Classification of dosages form
Solid dosages form
• Unit solid
• Bulk dosage form
Semi – solid dosages form
 Creams
 Ointment/Pastes
 Gels
 Suppositories
Cont..
Liquid dosages form
 Monophasic liquid
 Biphasic liquid
Gases dosages form
• Inhalations
• Aerosol sprays
Pharmaceutical dosages form
Dosage Form (DF) is defined as the physical form of
a dose of a chemical compound used as a drug or
medication intended for administration or
consumption.
The need for dosage forms :
• Accurate dose.
• Protection e.g. coated tablets scaled ampules.
• Protection from gastric juice.
• Masking taste and odour.
• Placement of drug within body tissues.
• Sustained release medication.
• Controlled release medication.
• Optimal drug action.
• Insertion of drug into body cavities ( rectal , vaginal ) .
• Use of desired vehicle for insoluble drug.
Classification of dosages form
Solid Semi- Solid Liquid Gas
1.Unit solid: tablets ,
capsules
Cream 1.Monophasic liquid:
syrup ,solution
Inhaler
2.Bulk dosage form:
powder ,Dusting
powder
Paste 2.Biphasic liquid:
emulsion ,suspension
aerosols
Gel
suppositories
Unit solid
Tablets:–
They are unit solid dosage forms
consisting of active ingredient
and suitable pharmaceutical
excipients. – They may vary in
size, shape, weight, hardness,
thickness, disintegration and
dissolution characteristics, and
in other aspects
e.g. Paracetamol 500 mg
Capsules:
They are unit solid dosage forms
consisting gelatin shell that breaks
open after the capsule has been
swallowed and releasing the drug.
e.g. Lansina-30
 Types :
 hard-shell gelatin capsule
e.g: Ampicillin capsule
 soft-shell gelatin capsule
e.g: Vitamin E cap
Bulk dosage form
Powder:
 They are bulk solid dosage forms
consisting two or more
medicament meant for internal
use.
 The size of particle range from
10,000 microns to 0.1microns.
 Size of the powder determine the
effectiveness of physiological
properties.
e.g: Nebanol 10 mg
Dusting powder
Dusting powder is a
powder used as a desiccant.
The pharmaceutical use of
talc as a dusting powder
depends on its desiccant
properties. Dusting powder
is a powder used as a
desiccant.
Semi – solid dosages form
Creams
Creams are semi-solid emulsions, that is mixtures
of oil and water. They are divided into two types-
 O/W TYPE
 W/O TYPE
O/W creams:
 which are composed of small droplets of oil
dispersed in a continuous aqueous phase.
W/O creams:
 which are composed of small droplets of
water dispersed in a continuous oily phase.
 Water-in-oil creams are more difficult to
handle.
Ointment/Pastes
 Pastes are semisolid dosage forms that
contain one or more drug substances
intended for topical application.
 Generally, pastes contain a higher
proportion of solid materials than
ointments.
Gels
A gel is a solid or semisolid
system of at least two
constituents, consisting of a
condensed mass enclosing and
interpenetrated by a liquid.
e.g. Orogel 5 gm
Suppositories
A suppository is a solid dosage form
that is inserted into the rectum
(rectal suppository), vagina (vaginal
suppository), or urethra (urethral
suppository), where it dissolves or
melts and exerts local or systemic
effects. Suppositories are used to
deliver medications that act both
systemically and locally.
e.g. Erian
Liquid
dosages form
Monophasic liquid
Syrups
do not contain alcohol and
are concentrated solutions of sugar,
water, and flavorings. They are
sweeter and more viscous than
elixirs. Most OTC cough
medications are syrup based and
don’t only carry the drug but also act
to soothe the inflamed mucous
membranes of the throat.
e.g.Tusca plus
Solutions
one homogenous
phase, prepared by dissolving
one or more solutes in a solvent.
e.g. Sinamin
Biphasic liquid
Emulsions
A dispersion system
consisting of two immiscible
liquids.
-o/w or w/o
-cloudy appearance.
Suspensions
A dispersion
system where solid particles are
dispersed in liquid phase.
Solid particles
called dispersed phase and liquid
called continuous phase.
Elixirs
Solutions that contain an
alcohol and water base, added
sugar and flavorings, e.g.
Tylenol; commonly used for
pediatric and elderly patients who
have difficulty swallowing tablets
or capsules
Liniments
Liniments are
alcoholic or oleaginous solutions,
suspensions, or emulsions of
medicinal agents intended for
external application to the skin,
generally by rubbing.
Inhalations
 Inhalations are finely
powdered drug substances,
solutions, or suspensions of
drug substances administered
by the nasal or oral
respiratory route for local or
systemic effects.
 Special devices are used to
facilitate administration.
Aerosol sprays
• Several different types of
pharmaceutical product
may be packaged in
pressurized dispensers,
known as aerosols.
• used as surface
disinfectants, wound or
burn dressing, relieve
irritation of bites
pharmaceutical dosage form

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pharmaceutical dosage form

  • 2. Presentation topics Pharmaceutical Dosages Form Kamrul Hasan Sabbir ID.171211001 9th batch, Pharmacy Department
  • 3. Overview Pharmaceutical dosages form Classification of dosages form Solid dosages form • Unit solid • Bulk dosage form Semi – solid dosages form  Creams  Ointment/Pastes  Gels  Suppositories
  • 4. Cont.. Liquid dosages form  Monophasic liquid  Biphasic liquid Gases dosages form • Inhalations • Aerosol sprays
  • 5. Pharmaceutical dosages form Dosage Form (DF) is defined as the physical form of a dose of a chemical compound used as a drug or medication intended for administration or consumption.
  • 6. The need for dosage forms : • Accurate dose. • Protection e.g. coated tablets scaled ampules. • Protection from gastric juice. • Masking taste and odour. • Placement of drug within body tissues. • Sustained release medication. • Controlled release medication. • Optimal drug action. • Insertion of drug into body cavities ( rectal , vaginal ) . • Use of desired vehicle for insoluble drug.
  • 7. Classification of dosages form Solid Semi- Solid Liquid Gas 1.Unit solid: tablets , capsules Cream 1.Monophasic liquid: syrup ,solution Inhaler 2.Bulk dosage form: powder ,Dusting powder Paste 2.Biphasic liquid: emulsion ,suspension aerosols Gel suppositories
  • 8.
  • 9. Unit solid Tablets:– They are unit solid dosage forms consisting of active ingredient and suitable pharmaceutical excipients. – They may vary in size, shape, weight, hardness, thickness, disintegration and dissolution characteristics, and in other aspects e.g. Paracetamol 500 mg
  • 10. Capsules: They are unit solid dosage forms consisting gelatin shell that breaks open after the capsule has been swallowed and releasing the drug. e.g. Lansina-30  Types :  hard-shell gelatin capsule e.g: Ampicillin capsule  soft-shell gelatin capsule e.g: Vitamin E cap
  • 11. Bulk dosage form Powder:  They are bulk solid dosage forms consisting two or more medicament meant for internal use.  The size of particle range from 10,000 microns to 0.1microns.  Size of the powder determine the effectiveness of physiological properties. e.g: Nebanol 10 mg
  • 12. Dusting powder Dusting powder is a powder used as a desiccant. The pharmaceutical use of talc as a dusting powder depends on its desiccant properties. Dusting powder is a powder used as a desiccant.
  • 13. Semi – solid dosages form
  • 14. Creams Creams are semi-solid emulsions, that is mixtures of oil and water. They are divided into two types-  O/W TYPE  W/O TYPE
  • 15. O/W creams:  which are composed of small droplets of oil dispersed in a continuous aqueous phase. W/O creams:  which are composed of small droplets of water dispersed in a continuous oily phase.  Water-in-oil creams are more difficult to handle.
  • 16. Ointment/Pastes  Pastes are semisolid dosage forms that contain one or more drug substances intended for topical application.  Generally, pastes contain a higher proportion of solid materials than ointments.
  • 17. Gels A gel is a solid or semisolid system of at least two constituents, consisting of a condensed mass enclosing and interpenetrated by a liquid. e.g. Orogel 5 gm
  • 18. Suppositories A suppository is a solid dosage form that is inserted into the rectum (rectal suppository), vagina (vaginal suppository), or urethra (urethral suppository), where it dissolves or melts and exerts local or systemic effects. Suppositories are used to deliver medications that act both systemically and locally. e.g. Erian
  • 20. Monophasic liquid Syrups do not contain alcohol and are concentrated solutions of sugar, water, and flavorings. They are sweeter and more viscous than elixirs. Most OTC cough medications are syrup based and don’t only carry the drug but also act to soothe the inflamed mucous membranes of the throat. e.g.Tusca plus
  • 21. Solutions one homogenous phase, prepared by dissolving one or more solutes in a solvent. e.g. Sinamin
  • 22. Biphasic liquid Emulsions A dispersion system consisting of two immiscible liquids. -o/w or w/o -cloudy appearance.
  • 23. Suspensions A dispersion system where solid particles are dispersed in liquid phase. Solid particles called dispersed phase and liquid called continuous phase.
  • 24. Elixirs Solutions that contain an alcohol and water base, added sugar and flavorings, e.g. Tylenol; commonly used for pediatric and elderly patients who have difficulty swallowing tablets or capsules
  • 25. Liniments Liniments are alcoholic or oleaginous solutions, suspensions, or emulsions of medicinal agents intended for external application to the skin, generally by rubbing.
  • 26.
  • 27. Inhalations  Inhalations are finely powdered drug substances, solutions, or suspensions of drug substances administered by the nasal or oral respiratory route for local or systemic effects.  Special devices are used to facilitate administration.
  • 28. Aerosol sprays • Several different types of pharmaceutical product may be packaged in pressurized dispensers, known as aerosols. • used as surface disinfectants, wound or burn dressing, relieve irritation of bites