5. Pharmaceutical dosages form
Dosage Form (DF) is defined as the physical form of
a dose of a chemical compound used as a drug or
medication intended for administration or
consumption.
6. The need for dosage forms :
• Accurate dose.
• Protection e.g. coated tablets scaled ampules.
• Protection from gastric juice.
• Masking taste and odour.
• Placement of drug within body tissues.
• Sustained release medication.
• Controlled release medication.
• Optimal drug action.
• Insertion of drug into body cavities ( rectal , vaginal ) .
• Use of desired vehicle for insoluble drug.
7. Classification of dosages form
Solid Semi- Solid Liquid Gas
1.Unit solid: tablets ,
capsules
Cream 1.Monophasic liquid:
syrup ,solution
Inhaler
2.Bulk dosage form:
powder ,Dusting
powder
Paste 2.Biphasic liquid:
emulsion ,suspension
aerosols
Gel
suppositories
8.
9. Unit solid
Tablets:–
They are unit solid dosage forms
consisting of active ingredient
and suitable pharmaceutical
excipients. – They may vary in
size, shape, weight, hardness,
thickness, disintegration and
dissolution characteristics, and
in other aspects
e.g. Paracetamol 500 mg
10. Capsules:
They are unit solid dosage forms
consisting gelatin shell that breaks
open after the capsule has been
swallowed and releasing the drug.
e.g. Lansina-30
Types :
hard-shell gelatin capsule
e.g: Ampicillin capsule
soft-shell gelatin capsule
e.g: Vitamin E cap
11. Bulk dosage form
Powder:
They are bulk solid dosage forms
consisting two or more
medicament meant for internal
use.
The size of particle range from
10,000 microns to 0.1microns.
Size of the powder determine the
effectiveness of physiological
properties.
e.g: Nebanol 10 mg
12. Dusting powder
Dusting powder is a
powder used as a desiccant.
The pharmaceutical use of
talc as a dusting powder
depends on its desiccant
properties. Dusting powder
is a powder used as a
desiccant.
14. Creams
Creams are semi-solid emulsions, that is mixtures
of oil and water. They are divided into two types-
O/W TYPE
W/O TYPE
15. O/W creams:
which are composed of small droplets of oil
dispersed in a continuous aqueous phase.
W/O creams:
which are composed of small droplets of
water dispersed in a continuous oily phase.
Water-in-oil creams are more difficult to
handle.
16. Ointment/Pastes
Pastes are semisolid dosage forms that
contain one or more drug substances
intended for topical application.
Generally, pastes contain a higher
proportion of solid materials than
ointments.
17. Gels
A gel is a solid or semisolid
system of at least two
constituents, consisting of a
condensed mass enclosing and
interpenetrated by a liquid.
e.g. Orogel 5 gm
18. Suppositories
A suppository is a solid dosage form
that is inserted into the rectum
(rectal suppository), vagina (vaginal
suppository), or urethra (urethral
suppository), where it dissolves or
melts and exerts local or systemic
effects. Suppositories are used to
deliver medications that act both
systemically and locally.
e.g. Erian
20. Monophasic liquid
Syrups
do not contain alcohol and
are concentrated solutions of sugar,
water, and flavorings. They are
sweeter and more viscous than
elixirs. Most OTC cough
medications are syrup based and
don’t only carry the drug but also act
to soothe the inflamed mucous
membranes of the throat.
e.g.Tusca plus
23. Suspensions
A dispersion
system where solid particles are
dispersed in liquid phase.
Solid particles
called dispersed phase and liquid
called continuous phase.
24. Elixirs
Solutions that contain an
alcohol and water base, added
sugar and flavorings, e.g.
Tylenol; commonly used for
pediatric and elderly patients who
have difficulty swallowing tablets
or capsules
25. Liniments
Liniments are
alcoholic or oleaginous solutions,
suspensions, or emulsions of
medicinal agents intended for
external application to the skin,
generally by rubbing.
26.
27. Inhalations
Inhalations are finely
powdered drug substances,
solutions, or suspensions of
drug substances administered
by the nasal or oral
respiratory route for local or
systemic effects.
Special devices are used to
facilitate administration.
28. Aerosol sprays
• Several different types of
pharmaceutical product
may be packaged in
pressurized dispensers,
known as aerosols.
• used as surface
disinfectants, wound or
burn dressing, relieve
irritation of bites