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Dr. Garima Gupta
Assistant Professor
Department of Psychology
Arya Mahila PG College (Admitted to the privileges of BHU)
Varanasi
 Differential Diagnosis was first mentioned by Emil Kraepelin.
 Abbreviation: DDx, ΔΔ, ddx, or DD,
 In DDx, patient's history and physical examination are analysed to
arrive at the correct diagnosis. It includes distinguishing a particular
disease/condition from others disease that have similar clinical
features.
 Differential diagnosis is a systematic method of differentially
diagnosing the pathology from one and other based on shared
sign/symptoms. Thus, it helps identifying the disorder that lacks
unique symptoms or signs.
 It is a systematic diagnostic method that are used to identify the
presence of a an actual disease where multiple alternatives are
plausible.
 Therefore, differential diagnosis is a process where we
distinguish disorders that are having similar signs and
symptoms. In this a comparison is done on the basis of
symptoms, where we rule out the possibility of all other
factors/conditions or disorders except the one that can best
account for the existing clinical feature.
 To sum up, differential diagnosis is a condition with more
than one possibility for the diagnosis. The clinician is
required to differentiate between these (more than one
pathology/condition) to determine the actual diagnosis and
plan for appropriate treatment.
*Google image https://www.google.com/search?q=differential+diagnosis&sa=N&biw=1280&bih=578&tbm=isch&source=iu&ictx=1&fir=wS0Lv9R3ANkfPM%252CVFS4DvdlXMFG_M%252C_&vet=1&usg=AI4_-
kSGHBCVsqS9kda2uTZVUN5AweDmeA&ved=2ahUKEwjD7LaXwtzwAhXrwTgGHbMfA9k4ChD1AXoECB0QAQ#imgrc=w5E7PXKKDgGFJM
1.A condition where the existing clinical
picture is probably associated with the
different etiological factors i.e. the
symptomatic features are same of
both the pathology but are associated
with different etiology.
2.Another condition where it’s required
is the pathology with considerable
amount of symptomatic overlap.
• To narrow down the working
diagnosis.
• To plan/guide medical evaluation
and treatment.
• To rule out life threatening
conditions.
• To assist the doctor to make the
correct diagnosis.
 Step-1: Collection of important information of patient. Collected
information is analyzed and synthesized to get clinical features.
 Step-2: Once, the clinical features are identified, an attempt is made
to find which feature is the most prominent part of the presenting
clinical picture.
 Step-3: When the most prominent symptoms are identified, the
clinician questions the patients and tests to rule in or rule out the
possibility of various disorders.
 The clinician tries to identify the possible cause or antecedent
and/or concomitant factors of the existing symptoms/clinical
pictures.
 Further, an attempt is made to rule in or out for the presence of
other associated clinical features.
 The duration of existing or presenting symptoms and the prominent
symptoms are decided

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Differential diagnosis

  • 1. Dr. Garima Gupta Assistant Professor Department of Psychology Arya Mahila PG College (Admitted to the privileges of BHU) Varanasi
  • 2.  Differential Diagnosis was first mentioned by Emil Kraepelin.  Abbreviation: DDx, ΔΔ, ddx, or DD,  In DDx, patient's history and physical examination are analysed to arrive at the correct diagnosis. It includes distinguishing a particular disease/condition from others disease that have similar clinical features.  Differential diagnosis is a systematic method of differentially diagnosing the pathology from one and other based on shared sign/symptoms. Thus, it helps identifying the disorder that lacks unique symptoms or signs.  It is a systematic diagnostic method that are used to identify the presence of a an actual disease where multiple alternatives are plausible.
  • 3.  Therefore, differential diagnosis is a process where we distinguish disorders that are having similar signs and symptoms. In this a comparison is done on the basis of symptoms, where we rule out the possibility of all other factors/conditions or disorders except the one that can best account for the existing clinical feature.  To sum up, differential diagnosis is a condition with more than one possibility for the diagnosis. The clinician is required to differentiate between these (more than one pathology/condition) to determine the actual diagnosis and plan for appropriate treatment. *Google image https://www.google.com/search?q=differential+diagnosis&sa=N&biw=1280&bih=578&tbm=isch&source=iu&ictx=1&fir=wS0Lv9R3ANkfPM%252CVFS4DvdlXMFG_M%252C_&vet=1&usg=AI4_- kSGHBCVsqS9kda2uTZVUN5AweDmeA&ved=2ahUKEwjD7LaXwtzwAhXrwTgGHbMfA9k4ChD1AXoECB0QAQ#imgrc=w5E7PXKKDgGFJM
  • 4. 1.A condition where the existing clinical picture is probably associated with the different etiological factors i.e. the symptomatic features are same of both the pathology but are associated with different etiology. 2.Another condition where it’s required is the pathology with considerable amount of symptomatic overlap.
  • 5. • To narrow down the working diagnosis. • To plan/guide medical evaluation and treatment. • To rule out life threatening conditions. • To assist the doctor to make the correct diagnosis.
  • 6.  Step-1: Collection of important information of patient. Collected information is analyzed and synthesized to get clinical features.  Step-2: Once, the clinical features are identified, an attempt is made to find which feature is the most prominent part of the presenting clinical picture.  Step-3: When the most prominent symptoms are identified, the clinician questions the patients and tests to rule in or rule out the possibility of various disorders.  The clinician tries to identify the possible cause or antecedent and/or concomitant factors of the existing symptoms/clinical pictures.  Further, an attempt is made to rule in or out for the presence of other associated clinical features.  The duration of existing or presenting symptoms and the prominent symptoms are decided