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1. ARE
YOU
READY?

2. TONGUE TWISTER
• There with the weather-beaten
weatherman.
• Imagine an imaginary menagerie
manager imagining managing an
imaginary menagerie.
• Three hundred thirty-three thousand
three hundred thirty-three.

6. DISCOVERY
OF
NUCLEUS

7. Oldest known depiction of cells and
their nuclei by Antonie van
Leeuwenhoek, 1719.

8.  Robert Brown
- introduced the word areola or
nucleus, in the cells of the flower's outer
layer.
 Matthias Schleiden
-name "Cytoblast" (cell builder).

9. Robert Remak and Rudolf Virchow
propagated the new paradigm that cells
are generated solely by cells ("Omnis
cellula e cellula").
The function of the nucleus clear only
later, after mitosis discovered and the
Mendelian rules 20th century).

10. CELL
NUCLEUS

11. CELL NUCLEUS
• Latin nucleus or
nuculeus,
meaning kernel.
• The control center of the
cell.
• It contains most of the
cell's genetic material.

12. PRIMARY FUNCTIONS:
• Repository of genetic information
• Enables synthesis of nearly all proteins
• Houses the nucleolus
• Responsible for production of
ribosomes.
• Selective transportation of regulatory
factors and energy.

13. COMPOSITION

14. NUCLEAR ENVELOPE
 separates the cell's genetic material from
surrounding cytoplasm.
 serve as a barrier between nucleoplasm
and the cytoplasm.

15. NUCLEOPLASM
 made up of water and other
dissolved substances.
 act as a suspension for organelles
 maintains the shape of the nucleus.

16. NUCLEAR PORE
 composed of multiple proteins
 allows the passage of molecules
from inappropriate entering or
exiting the nucleus.

17. NUCLEAR LAMINA
• structural support for the nuclear
envelope
• anchoring sites for chromosomes
and nuclear pores.

18. PROGERIA
• Defective Lamina
protein makes the
nucleus unstable. That
nuclear instability
appears to lead to the
process of premature
aging in Progeria.

19. CHROMOSOMES
 Multiple linear DNA molecules.
 During most of the cell cycle
these are organized into chromatin
 During cell division the chromatin can
be seen to form the well-defined
chromosomes.

20. NUCLEOLUS
 synthesize rRna and assemble
ribosomes.

21. HAVE
YOU LEARNED?

22. Which of the following parts of
nucleus is responsible for the
formation of the ribosomes?
nucleoplasm
nucleolus
nuclear
envelope
chromosomes
A
B nucleolus
C
D

23. In the nucleus of eukaryotic cells, the genetic
material is complexed with protein and
organized into linear structures called:
A centrioles
chromosomes
histones plasmids
B
C D

24. Provide structural support for the nuclear
envelope and anchoring sites for
chromosomes and nuclear pores.
A Nucleoplasm
C
Cytosol
Nuclear Lamina
B
D
Nuclear
Membrane

25. The space between the
membranes is called:
perinuclear
space
internuclear
space
nuclear space
none of these
A
B
C
D
perinuclear
space

26. It prevents larger molecules, such as
nucleic acids and larger proteins, from
inappropriately entering or exiting the
nucleus.
nuleolus
nuclear
envelope
nuclear lamina
A
B
C
D nuclear pores

27. It serves as a barrier that prevent
macromolecules from diffusing freely
between the nucleoplasm and cytoplasm.
nuleolus
nuclear
envelope
nuclear lamina
nuclear pores
A
B
C
D

28. ASSIGNMENT:
In 1 whole sheet of paper give a brief
description of the following:
• DNA
• Histone
• Centromere
• Telomere