Mock question paper for neet pg, usmle, plab and fmge (mci screening exam) on mycoplasma

Q:1
Granulomatous inflammatory reaction is caused by all of the following organisms,
EXCEPT:
A: M. Tuberculosis
B: M. Leprae
C: Yersinia pestis
D: Mycoplasma
Correct Ans:D
Explanation
Mycoplasma pneumoniae produce acute self limited lower respiratory tract infection
which mostly affects children, and young adults. pneumonia caused by Mycoplasma
shows patchy consolidation of the lung. The alveoli shows interstitial process with
reactive alveolar lining cells and mononuclear infiltration. It does not cause
granulomatous inflammatory reaction.

A granuloma is defined as a nodular lesion caused by the accumulation of mononuclear
leukocytes resulting from a chronic inflammatory reaction. Mycobacteria induced
tuberculosis and leprosy are examples of infectious agent induced granulomatous
disease.

Ref: Essentials of Rubin's Pathology edited by Emanuel Rubin, page 174.
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Q:2 Which of the following microorganism has sterol in the cell wall?
A: Mycoplasma
B: Virus
C: Fungi
D: Protozoa
Correct Ans:A
Explanation
The mycoplasmas are cell walllacking bacteria that do not synthesize the precursors
of peptidoglycan. A unique characteristic is that some genera require cholesterol for
growth; unesterified cholesterol is a unique component of the membranes of both sterol
requiring and non–sterolrequiring species if present in the medium.

Ref: Brooks G.F. (2013). Chapter 3. Classification of Bacteria. In G.F. Brooks (Ed),
Jawetz, Melnick, & Adelberg's Medical Microbiology, 26e.
Q:3 Which of the following is the most common pathogens responsible for nosocomial

pneumonias in the ICU?
A: Gram positive bacteria
B: Gram negative bacteria
C: Mycoplasma
D: Virus infections
Correct Ans:B
Explanation
Most common organisms causing nosocomial pneumonia are gram negative bacteria
in 5070% cases, which reach the lower airways by aspiration of gastric contents or by
microaspiration of upper airway secretions. Most common organism is pseudomonas
aeruginosa followed by enterobacteriacea. Staphylococci aureus is second to gram
negative bacteria and accounts for 15 30%. Anaerobic bacteria is found in 1030%
cases.
Ref: Infectious Diseases By Sherwood L. Gorbach, 3rd Edition, Page 477
Q:4 Penicillin would be LEAST effective in treating:
A: Syphilis
B: Streptococcal pharyngitis
C: Pneumococcal pneumonia
D: Mycoplasma pneumonia
Correct Ans:D
Explanation
Mycoplasma organisms do have a cell wall and are therefore resistant to penicillin.
Other forms of bacteria that lack a cell wall are spheroplasts and protoplasts, which are
formed from gramnegative and grampositive bacteria, respectively, through the
action of penicillin or by other procedures that remove the cell wall or interfere with
its formation. The other organisms listed in the question are all susceptible to the
action of penicillin. Tetracyclines, erythromycin and the aminoglycosides are effective
antibiotics for the treatment of mycoplasmal infections.
Ref: Infection and Immunity By Huw Davies, D. H. Davies, Page 34
Q:5
Which of the following mycoplasmas has been implicated as a cause of
nongonococcal urethritis (NGU)?
A: Mycoplasma hominis

B: M.pneumoniae
C: M.fermentans
D: Ureaplasma urealyticum
Correct Ans:D
Explanation
Ureaplasma urealyticum has been associated with nongonococcal urethritis (NGU) as
well as infertility. Mycoplasma pneumoniae is the etiologic agent of primary atypical
pneumonia. M. hominis, although isolated from up to 30% of patients with NGU, has
yet to be implicated as a cause of that disease. M. fermentans has on rare occasions
been isolated from the oropharynx and genital tract. M. mycoides causes bovine
pleuropneumonia.
Note:
Ureaplasmas can be distinguished from mycoplasmas by their ability to produce the
enzyme urease, which degrades urea to ammonia and carbon dioxide.

Ref: Brooks G.F., Carroll K.C., Butel J.S., Morse S.A., Mietzneron T.A. (2010).
Chapter 25. Mycoplasmas & Cell WallDefective Bacteria. In G.F. Brooks, K.C.
Carroll, J.S. Butel, S.A. Morse, T.A. Mietzneron (Eds), Jawetz, Melnick, & Adelberg's
Medical Microbiology, 25e.
Q:6 TRUE about mycoplasma are all, EXCEPT:
A: They are L forms
B: Sterol enhances growth
C: Can grow in cell free media
D: When grown in liquid medium do not produces turbidity
Correct Ans:A
Explanation
The organisms have diameters of about 0.2 to 0.3 mm, but they are highly plastic and
pleomorphic and may appear as coccoid bodies, filaments, and large multinucleoid
forms. They do not have a cell wall and are bounded only by a single triplelayered
membrane, which, unlike bacteria, contains sterols. The sterols are not synthesized by
the organism, but are acquired as essential components from the medium or tissue in
which the organism is growing. Lacking a cell wall, Mycoplasma and Ureaplasma
stain poorly or not at all with the usual bacterial stains. Hemadsorption is a feature of
M pneumoniae. Because of their small size mycoplasma usually do not produce
turbidity in liquid media.

Ref: Ray C.G., Ryan K.J. (2010). Chapter 38. Mycoplasma and Ureaplasma. In C.G.
Ray, K.J. Ryan (Eds), Sherris Medical Microbiology, 5e.

Q:7 The following is lure for Mycoplasmas except:
A: Multiply by binary fission
B: Are sensitive to betalactam group of drugs
D: Require sterols for their growth
Correct Ans:B
Explanation
GENERAL CHARACTERISTICS OF MYCOPLASMAS:
Very small(0.20.3 µm) .
Can pass through bacterial filters.
Lack a rigid cell wall.
Bound by a single trilaminar cell membrane that contains a sterol.
Extremely pleomorphic varying in shape from coccoid to filamentous to other
bizzare forms.
Mycoplasma, Ureaplasma, Spiroplasma and Anaeroplasma cannot synthesize
their own cholesterol and require it as a growth factor in culture medium.
Acholeplasma synthesizes carotenol as a substitute for cholesterol, but will
incorporate cholesterol if it is provided.
Insensitive to cellwall active antibiotics such as penicillins and cephalosporins.
Limited biosynthetic capabilities due to a small genome.
Multiply by binary fission. However, cytoplasmic division may lag behind
genome division. This results in the formation of multinucleate filaments and
other shapes.
Do not possess flagellae or pili, but some mycoplasmas including M.
pneumoniae, exhibit gliding motility on liquidcovered surfaces. This is
attributed to specialized tip structures that also help the organisms in the
attachment to the cell.
Non sporing
Stain poorly with Grams stain. Can be stained with Giemsa and Dienes
methods.
Are considered as stable L forms by some researchers but this hypothesis is still
not fully accepted.
Aerobes and facultative anaerobes except Anaeroplasma which is strictly
anaerobic.
For primary isolation, an atmosphere of 95% Nitrogen and 5% Carbon dioxide
is preferred.
They can grow within a temperature range of 2241°C, the parasitic species
growing optimally at 3537°C.
For fermentative organisms, the initial pH of the medium is adjusted to 7.37.8,
for arginine metabolizing organisms it should be around 7 and for ureaplasmas,
range of pH should be 66.5.
PPLO broth/agar and SP4 media are used for isolation of mycoplasmas.
Fried egg colony morphology is obtained on culture media.
Ref : Textbook of Microbiology by Dr. D.R. Arora; 3rd edition & Mackie McCartney
Practical Medical Microbiology; 14th edition

Q:8
Which among the following is known as ‘Eaton agent’ which causes respiratory
infection?
A: Corynebacterium
B: Pseudomonas
C: Mycoplasma
D: Streptococcus
Correct Ans:C
Explanation
M. pneumoniae pneumonia is also referred to as Eaton agent pneumonia (the
organism having first been isolated in the early 1940s by Monroe Eaton), primary
atypical pneumonia, and "walking" pneumonia.

A mild tracheobronchitis with fever, cough, headache, and malaise is the most
common syndrome associated with acute M pneumoniae infection. The pneumonia is
typically less severe than other bacterial pneumonias. It has been described as
"walking" pneumonia because most cases do not require hospitalization.

Ref: Hardy R.D. (2012). Chapter 175. Infections Due to Mycoplasmas. In D.L. Longo,
A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo (Eds), Harrison's
Principles of Internal Medicine, 18e.
Q:9 Mycoplasma pneumoniae (Eaton agent) is an infectious agent that:
A: Lacks steroids in its cytoplasmic membrane
B: Contains muramic acid in its cell wall
C: Contains only DNA
D: Causes primary atypical pneumonia
Correct Ans:D
Explanation
Mycoplasma pneumoniae is the causative agent of primary atypical pneumonia, which
was initially described by Eaton, giving rise to the eponym Eaton agent. Mycoplasma
pneumoniae requires sterols for growth, usually in the form of cholesterol that is
incorporated into the cell membrane. Mycoplasma pneumoniae lacks muramic acid in
its cell wall as do all microorganisms belonging to genus Mycoplasma.
Similarly, and in harmony with other species of the genus, Mycoplasma pneumoniae
contains both DNA and RNA. Mycoplasma pneumoniae is completely resistant to
Penicillin, which inhibits cell wall synthesis, because Mycoplasma pneumoniae does
not have a cell wall. Mycoplasma may cause a hemolytic anemia (cold agglutination).

Q:10 'Stalactite' growth is a feature of the following organism:
A: Haemophilus
B: Pasteurella
C: Corynebacterium
D: Mycoplasma
Correct Ans:B
Explanation
'Stalactite' growth is a feature of Pasteurella pestis.

If Pasteurella pestis (Yersinia pestis) grown in a flask or broth with oil or ghee
(clarified butter) floated on top (ghee broth) a characteristic growth occurs which
hangs down into the broth from the surface, resembling stalactites (stalactite growth).

Ref: Textbook of Microbiology By Ananthanarayan And Paniker, 6th edition, Page
299.
Q:11
A 24 year old female has fever, malaise, and a dry, nonproductive cough. She
also complains of headache, muscle aches, and leg pain. Lab values are
significant for elevated cold agglutinins. Which of the following microorganisms
is responsible for her symptoms?
A: Haemophilus influenzae
B: Klebsiella pneumoniae
C: Legionella pneumophila
D: Mycoplasma pneumoniae
Correct Ans:D
Explanation
Mycoplasma pneumoniae is a wallless bacterium that causes interstitial pneumonia in
young adults. Elevated cold agglutinins (a classic clue) are found in about half of the
patients. The cold agglutinins are IgM antibodies. M. pneumoniae may be diagnosed
by sputum or complement fixation.

Haemophilus causes bronchopneumonia in babies and children, and may occur in
debilitated adults.

Klebsiella causes a bronchopneumonia with patchy infiltrates involving one or more
lobes. Think red currant jelly sputum. It frequently occurs in debilitated patients,

diabetics, and alcoholics. Note that these organisms are highly encapsulated and
produce mucoid colonies on lab media.

Legionella lives in contaminated water sources such as air conditioning systems.

Q:12
A 14 year old girl with cystic fibrosis is admitted to the hospital with fever and
shortness of breath, and is diagnosed with pneumonia. During a respiratory
therapy session, she coughs up mucus that is distinctly greenish in color. Which
of the following organisms should be suspected?
A: Klebsiella pneumoniae
B: Mycoplasma pneumoniae
C: Pneumocystis carinii
D: Pseudomonas aeruginosa
Correct Ans:D
Explanation
The clues suggesting infection with Pseudomonas aeruginosa are the greentinged
sputum (due to the formation of blue and green pigments by P. aeruginosa), and the
association with cystic fibrosis. Unfortunately, P. aeruginosa is very difficult to treat
with most antibiotics, and presents a very difficult therapeutic challenge in the
management of cystic fibrosis patients.
Klebsiella pneumoniae is most often seen in alcoholics, the elderly, and diabetics.
Mycoplasma pneumoniae is a common cause of communityacquired atypical
pneumonia, and is characterized by a dry, nonproductive cough.
Pneumocystis carinii usually causes pneumonia in immunocompromised patients, e.g.,
AIDS patients.

Ref: Brooks G.F. (2013). Chapter 16. Pseudomonads, Acinetobacters, and Uncommon
GramNegative Bacteria. In G.F. Brooks (Ed), Jawetz, Melnick, & Adelberg's Medical
Microbiology, 26e.
Q:13
A 19 year old college student presents to the student health clinic complaining of
weakness, malaise, and a chronic cough. He has a fever of 100 degrees F and a
dry cough; no sputum can be obtained for laboratory analysis, so a bronchial
lavage is performed and the washings are submitted to the laboratory. The
laboratory reports that the organism is "slowgrowing."Serodiagnosis reveals
Strep MG agglutinins in the patient's serum. Which of the following organisms
is the most likely cause of this student's illness?
A: Klebsiella pneumoniae

B: Mycoplasma pneumoniae
C: Parainfluenza virus
D: Respiratory syncytial virus
Correct Ans:B
Explanation
The patient has primary atypical pneumonia caused by Mycoplasma pneumoniae. This
organism is fastidious and difficult to culture in the laboratory, however serodiagnosis
can be most helpful. Patients typically produce one or two heterophile antibodies
during the course of the infection; one agglutinates human O+ RBCs in the cold (the
cold hemagglutinin) while the other causes the agglutination of a strain of
Streptococcus salivarius termed strain MG (the Strep MG agglutinins).

Klebsiella pneumoniae is readily cultured on routine laboratory media and
characteristically produces pneumonia with blood clots in the sputum (red currant
jelly sputum), which may be indicative of pulmonary abscess development.

Parainfluenza viruses cause croup, which is characterized by a dry, "barking" cough.
It is more of a tracheitis, bronchitis, and bronchiolitis than a pneumonitis. No
heterophile antibodies are produced in these patients.

Respiratory syncytial virus causes an atypical pneumonitis in infants. It is usually
diagnosed by the observation of syncytial masses in respiratory secretions. Cold
hemagglutinins and Strep MG agglutinins are absent.

Ref: Levinson W. (2012). Chapter 23. Mycoplasmas. In W. Levinson (Ed), Review of
Medical Microbiology & Immunology, 12e.
Q:14 Vincent's angina is caused by :
A: Mycoplasma
B: Fusiformis
C: Microaerophilic streptococci
D: Treponema pallidum
Correct Ans:B
Explanation
Vincent's angina is an acute pseudomembranous involvement of the pharynx or
tonsils.It may start as aseptic necosis secondary to capillary staisis due to poor oral
hygeine,local irritation from food impaction,smoking,trauma,stress and endocrine or
metabolic distrubances.The disease is most likely secondary to a combination of
fusospirochetal organisms(most often fusobacterium nucleatum and treponema
vincentii.

Ref : Infectious Diseases edited by Sherwood L. Gorbach, John G. Bartlett, Neil R.
Blacklo

Q:15
Kamla, a 30 yrs old lady examined for infertility by hysterosalpingography,
reveals 'Beadlike' fallopian tube and clubbing of ampulla. Most likely cause is:
A: Gonococcus
B: Mycoplasma
C: Chlamydia
D: Mycobacterium tuberculosis
Correct Ans:D
Explanation
'Beadlike' fallopian tube and clubbing of ampulla in a case of infertility indicates
previous infection with Mycobaterium tuberculosis.
Ref: Shaw’s Textbook of Gynaecology, 12th Edition, Page 119 ; Textbook of Gynecology By D C
Dutta, 4th Edition, Page 132
Q:16 Life threatening intravascular hemolysis occurs with sepsis due to which
organism?
A: Clostridium perfringens
B: Mycoplasma pneumonia
C: Pseudomona
D: Klebsiella
Correct Ans:A
Explanation
Life threatening intravascular hemolysis due to a toxin with lecithinase activity is seen
in clostridium perfringens sepsis.

Ref: Harrison's principles of internal medicine, 18th edition, Page 881.
Q:17 Which among the following is the drug of choice in Mycoplasma infection?
A: Doxycycline
B: Penicillin
C: Ceftriaxone

D: Cotrimoxazole
Correct Ans:A
Explanation
For mycoplasma tetracyclines are the drugs of choice (doxycycline 100 mg 2 times a day for 10 to
14 days). Erythromycin, Azithromycin and Fluroquinolones can also be used.
Tetracyclines are contraindicated in pregnancy, therefore erythromycin or spiramycin
can be used.
Q:18 The MOST COMMON causative organism for community acquired pneumonia is:
A: Streptococcus pneumoniae
B: Haemophilus influenzae
C: Mycoplasma pneumoniae
D: Chlamydia pneumoniae
Correct Ans:A
Explanation
Although Streptococcus pneumoniae is most common pathogen causing community
aquoired pneumonia. Data suggest that a virus may be responsible for up to 18% of
cases of CAP that require admission to the hospital.
Ref: Harrison, E18,P2131.
Q:19 Which of the following etiological agents corresponds with pyelonephritis?
A: Mycoplasma pneumoniae
B: Mycoplasma hominis
C: Ureaplasma urealyticum
D: All of the above
Correct Ans:B
Explanation
Mycoplasma hominis colonizes lower genitourinary tract of almost 50% healthy
sexually active adults. It is an opportunist pathogen that can invade upper
genitourinary tract and cause infections. It adheres to the epithelial cells of mucosal
surfaces in urogenital tract and can not be eliminated by mucosal secretion and urine.
It is mostly resistant to erythromycin but sensitive to tetracycline and lincomycin.

It is associated with following infections in adults:
Pyelonephritis
Salpingitis
Pelvic inflammatory disease
Postabortal fever
Postpartum fever
Ref: Brooks G.F. (2013). Chapter 25. Mycoplasmas and Cell Wall–Defective Bacteria. In
G.F. Brooks (Ed), Jawetz, Melnick, & Adelberg's Medical Microbiology, 26e.
Q:20 Fried Egg Colonies are produced by?
A: Chlamydia
B: Mycoplasma
C: Niesseria
D: Diphtheria
Correct Ans:B
Explanation
(67) Mycoplasma
REF: Jawetz 24th edition Section III. Bacteriology Chapter 26
Mycoplasma Cultures:
1. The material is inoculated onto special solid media and incubated for 310 days at
37°C with 5% CO2 (under microaerophilic conditions), or into special broth and
incubated aerobically. One or two transfers of media may be necessary before growth
appears that is suitable for microscopic examination by staining or
immunofluorescence. Colonies may have a "Fried Egg" appearance on agar.
Q:21
A patient (pigeon handler) presents with interstitial pneumonitis accompanied by
headache, backache, and a dry, hacking cough. A pale, macular rash is also found on
the trunk (Horder's spots). Likely organism is:
A: Histoplasma
B: Chlamydiae
C: Mycoplasma
D: Aspergillus
Correct Ans:B

Explanation
Chlamydiae
Q:22 Metachromatic granules are found in
A: Diphtheria
B: Mycoplasma
C: Staphylococcus
D: All
Correct Ans:A
Explanation
Ans. is 'a' i.e., Diphtheria
Q:23 Lform is seen in
A: Ricketsia
B: Chlamydia
C: Mycoplasma
D: H. pylori
Correct Ans:C
Explanation
Ans. is 'c' i.e., Mycoplasma
Lforms are seen in several species of bacteria, developing either spontaneouly
or in presence of penicillin or other agents that interfere with cell wall synthesis.
Lforms may be unstable in that the morphological abnormality is maintained
only in the presence of penicillin, or
stable, when the aberrant form becomes the permanent feature of the strain and
is retained in serial subcultures.
Lform resemble mycoplasma and it is possible that mycoplasma represent stable
Lforms of as yet unidentified parent bacteria.

Q:24 The following statements are true with reference to Mycoplasma except
A:
They are the smallest prokaryotic organisms that can grow in cell free culture
media
B: They are obligate intracellular organisms
C: They lack a cell wall
D: They are resistant to Betalactam drugs
Correct Ans:B
Explanation
Ans. is 'b' i.e., They are obligate intr acellular organisms
Morphology
.  Smallest free living organism, are prokaryotes
.  Lack cell wall, are bounded by a triple layered unit membrane that contains sterol
(therefore mycoplasmas require sterol for growth).
. Their lack of cell wall is associated with cellular pleomorphism and resistance to cell
wall active antimicrobial agents, such as penicillins and cephalosporins lactam drugs).
. Multiplication is by binary fission.
.  Non sporing
. Do not posses flagella or fimbria.
. Mycoplasma can be cultivated in fluid or solid media (cell free media).
Biochemical reactions
. Mycoplasmas are chemoorganotrophs, the metabolism being mainly fermentative.
. Most species utilize glucose or arginine as the major source of energy.
. Urea is not hydrolyzed, except by ureoplasmas.
. Unique among prokaryotes is the requirment of most mycoplasmas for cholesterol and
related sterols.
.  Mycoplasmas lack the ability to synthesize purine and pyrimidines.
Q:25 Diene's method is used for
A: Mycoplasma
B: Chlamydiae
C: Plague

D: Diphtheria
Correct Ans:A
Explanation
Ans. is 'a' i.e., Mycoplasma
Culture
.  May be cultivated in fluid or solid media.
.  Generally facultative anaerobes, growth being better aerobically. But, since
organisms from primary tissue specimens frequently grow under anaerobic
conditions, an atmosphere of 95% N2 and 5% CO2 is preferred.
.  Grow in heart infusion peptone broth with 2% agar (pH 7.8) (PRL.O. broth) with fresh
yeast extract and horse serum.
.  For enrichement, 30% human ascitic fluid or animal serum (horse, rabbit) are
added to the medium. (Serum acts as a source of cholesteral).
.  The colony gives 'fried egg' appearance.
.  Colonies are best studied after staining by Dienes method.
.  Most mycoplasma colonies are hemolytic (63 hemolysis) due to production of
hydrogen peroxide. Remember
.  Dienes phenomenon is used to detect swarming of proteus.
Q:26 In reference to the mycoplasmas, the following are true except
A: They are inhibited by penicillins
B: They can reproduce in cell free media
C: They have an affinity for mammalian cell membranes
D: They can pass through filters of 450 nm pore size
Correct Ans:A
Explanation
Ans. is 'a' i.e., They are inhibited by penicillins
.  Their (mycoplasmas) lack of cell wall is associated with cellular pleomorphism and
resistance to cell wall active antimicrobial agents, such as penicillins and
cephalosporins.
.  Because of their plasticity, they can pass through bacterial filters and have often
been mistaken for viruses. The smallest mycoplasmas are 125250 nm in size so they

can easily pass through bacterial filters 450 nm in size. They are free living in nature,
self replicating on a laboratory media.
About option 'c'
.  Mycoplasmas generally produce surface infections by adhering to the surface of host
cell.
Adherence is necessary for colonization and infection.
Remember
.  The genome of mycoplasma genitalium is the smallest known so far.
Mycoplasmas have limited biosynthetic abilities, so that they need a rich growth
medium containing natural animal protein and in most cases a sterol
component.
Q:27 True about mycoplasma are all except ?
A: They are L forms
B: Sterol enhances growth
D: When grown in liquid medium do not produces turbidity
Correct Ans:A
Explanation
Ans. is 'a' i.e., They are L forms
Features of mvcoplasma
.   Mycoplasmas are unique organisms because they have a very small size similar to
viruses but unlike viruses, they have an independent existence i.e. they can grow in cell
free media.
Though they can grow in cell free media but they have a limited biosynthetic
ability to they need a rich growth medium containing natural animal protein
(usually blood serum) and in most cases a sterol component.
.  The sterol component is required because mycoplasma contains sterol in their cell
membrane.
.  Mycoplasmas are also unique because they do not have a regular cell wall instead
they are bound by a cell membrane consisting primarily of sterol.
The absence of the cell wall gives two characteristic properties to mycoplasma
i)         The absence of cell wall makes them highly pleomorphic.

ii)      Mycoplasmas are completely resistant to penicillin because, they lack the cell wall
structure at which penicillin acts instead they are inhibited by tetracycline or
erythromycin.
Mycoplasma and L forms of bacteria (cell wall defective bacteria)
L phase bacteria are cell wall defective bacteria that can replicate serially as non
rigid cells and can produce colonies on solid media.
.    L forms develop when many bacteria either spontaneously or induced by certain
cell wall inhibiting drugs lose part or all of their cell wall and develop into L forms.
Some L phase variants are stable, others are unstable and revert to their
bacterial parental forms.
It has been suggested that mycoplasmas may represent stable L forms of
bacteria but genetic, antigenic and biochemical evidence are against the
possibility.
.  The characteristic of the cell wall defective forms may be similar to those of
mycoplasma but by definition, mycoplasmas do not revert to parental bacterial forms or
originate from them. There is no genetic relationship  between mvcoplasmas and cell wall
defective microbial forms or their parent bacteria.
About option `d'
Mycoplasma and ureoplasma ureolyticum do not produce turbidity in liquid medum.
— www.springerlink.com
Q:28 Mycoplasma pneumonia is characterised by all except?
A: Diagnosed by serum cold antibody
B: Treatment is erythromycin
C: Cannot be cultured from sputum
D: Raised ESR
Correct Ans:C
Explanation
Ans. is 'c' i.e., Can not be cultured from sputum
. Laboratory diagnosis of mycoplasmal primary atypical pneumonia may be established
either by isolation of the mycoplasma or by serological methods.
. Mycoplasma can be cultured in fluid or solid media. A widely used isolation medium
is PPLO broth.
.  Specimens are :
1. Throat swabs                        3. Inflammatory exudates

2. Sputum                                 4. Respiratory secretions
Treatment of Mycoplasma pneumonia
About other options
. In a patient with a compatible clinical picture, a cold agglutinin titre of 1 : 32 supports
the diagnosis of mycoplasma pneumonia.
.    Cold agglutinins are nonspecific but develop within the first 7 to 10 days.
.   The test can also be performed at the bedside.
.     ESR, may be raised in 50% of the patients.
Q:29 Which one of the following bacteria contains mycolic acid in the cell wall?
A: Escherichia
B: Mycoplasma
C: Mycobacteria
D: Staphylococcus
Correct Ans:C
Explanation
Ans. is 'c' i.e., Mycobacteria
Q:30 Mycoplasma infection simulates?
A: Pneumococcal pneumonia
B: Viral pneumonia
C: Hypersensitivity pneumonia
D: Aspiration pneumonia
Correct Ans:B
Explanation
Ans. is 'b' i.e., Viral pneumonia

Mock question paper for neet pg, usmle, plab and fmge (mci screening exam) on mycoplasma

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Mock question paper for neet pg, usmle, plab and fmge (mci screening exam) on mycoplasma