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Jeevan kishore
Group – 16
4th year 2nd semester
Tbilisi statemedical university
ISCHEMIC HEART DISEASE
TREATMENT…
WHAT IS ISCHEMIC HEART DISEASE???
reduced blood
supply to heart…
by blockage in
the coronary
arteries or
narrowing…
CLASSIFICATION…
Sudden cardiac death…
Acute coronary syndrome…
- Myocardial infarction and unstable
angina pectoris
Stable angina pectoris…
Why treatment???
TREATMENT ???
Because it is a disease… and according
to our profession, we must treat
disease…
It is a life threatening problem which
can kill a person if left untreated and
so we must treat …
METHODS OF TREATMENT…
PHARMACOLOGICAL THERAPY
SURGICAL METHODS
NON INVASIVE METHODS
PHARMACOLOGICAL
THERAPY…
Therapy is aimed in restoring balance between
myocardial oxygen supply and demand…
Useful agents:
Nitrates…
beta-blockers …
calcium channel blockers…
NITRATES
Dilates arteries to the heart and increases blood flow to
the heart…
Dilates veins throughout the body to hold more blood,
thus reducing amount of blood going back to heart and
reducing heart workload…
Helps to relieve angina when used before doing some
stressful activities that can cause angina…
If usual dose of nitroglycerin doesn’t show relieve for
angina, that means that it is becoming more worse… call
a doctor immediately…
Isosorbidemononitrate,dinitrate,nitroglycerine
SIDE EFFECTS…
CALL EMERGENCY SERVICES RIGHT AWAY
IF YOU HAVE:
Trouble breathing.
Swelling of your face, lips, Tongue
or throat.
Hives.
Blurred vision.
Severe headache that does not go
away.
Skin rash.
COMMON SIDE EFFECTS OF
THIS MEDICINE INCLUDE:
Dizziness or light
headedness.
Headache.
Flushing, or feeling
warm, in the face
and neck.
Nausea.
Isosorbidemononitrate,dinitrate,nitroglycerine
BETA-BLOCKERS
Reduce workload of heart by slowing the
heart rate…
Help lower the blood pressure which helps to
lower the risk of heart disease, heart attack
and stroke…
Useful for patients with heart attack to avoid
future attacks…
Metoprolol,carvediol,labetalol,atenolol,nebivolol
CONTRAINDICATIONS…
Symptomatic CHF…
History of bronchospasm…
Bradycardia or AV block…
Peripheral vascular disease with s/s of
claudication…
Metoprolol,carvediol,labetalol,atenolol,nebivolol
SIDE EFFECTS…
CALL EMERGENCY
SERVICES RIGHT
AWAY IF YOU HAVE:
Trouble
breathing.
Swelling of your
face,
lips, tongue, or
throat.
Fainting or
severe dizziness.
CALL YOUR
DOCTOR RIGHT
AWAY IF YOU
HAVE:
Hives.
A very slow heart rate
(less than 50 beats per
minute).
Swelling in your legs or
feet.
Shortness of breath.
Cold hands and feet.
COMMON SIDE
EFFECTS OF THIS
MEDICINE INCLUDE:
Dizziness
Feeling tired.
Trouble
sleeping.
Metoprolol,carvediol,labetalol,atenolol,nebivolol
CALCIUM CHANNEL BLOCKERS…
Increases blood flow to the heart by dilating
coronary arteries…
Prevent spasm of the coronary arteries…
Lower blood pressure and heart’s workload, so that
heart muscle functions with less oxygen and blood
flow…
Controls irregular heart rhythms…
Amlodipine,diltiazem,nicardipine,nifidipine,
verapamil
SIDE EFFECTS
CALL EMERGENCY SERVICES
RIGHT AWAY IF YOU HAVE:
Trouble breathing.
Swelling of your face,
lips, tongue, or throat.
Hives
COMMON SIDE EFFECTS OF THIS
MEDICINE INCLUDE:
Slow heart rate.
Swelling in the lower legs
or ankles.
Constipation or diarrhoea.
Dizziness or light headedness.
Flushing or feeling warm.
Amlodipine,diltiazem,nicardipine,nifidipine,
verapamil
COMBINATION DRUGS…
Nitrate and beta blocker
Nitrate and verapamil or cardizem for similar reasons
Long acting dihydropyridine calcium channel blocker
and beta blocker
A dihydropyridine and nitrate is often not tolerated
without concomitant beta blockade because of marked
vasodilatation with resultant head ache and increased
heart rate
SURGICAL METHODS…
Angioplasty
Atherectomy
Coronary artery bypass
grafting
ATHERECTOMY…
It is alternative to angioplasty.
It results in cutting of plagues from the vessels.
There are 4 types of atherectomy devices :
CARDIAC REHABILITATION
prescribed after angina or angioplasty or cabg or
heart attack…
rehabilitation when recommended with surgery
and medicinal treatment helps in recovery faster…
it has 2 types of programme :
Exercise training
Educational and counselling training
NON-INVASIVE TREATMENT
• ENHANCED EXTERNAL COUNTER PULASTION IS THE
NON-INVASIVE TREATMENT OF ISCHEMIA.
The 3 pneumatic cuffs are wrapped around patient legs and
connected to telemetry monitors.
Telemetry monitors the heart rate and rhythm.
Cuffs are wrapped on the calves, lower thighs and upper thighs
or buttocks.
Cuffs are timed to inflate and deflate based on patient ECG.
Inflation is at the beginning of diastole.
Deflation is at the beginning of systole.
1st calves are inflated then lower thighs and then upper thighs
at about 200mmHg.
This decreases afterload and increases the preload of heart.
Indications…
Angina patients who are not relieved
by medicine
Patients who don’t want to
have bypass surgery
Patients who are contraindicated for
bypass or angioplasty due to kidney
failure, liver failure,
severe COPD cases, diffuse diabetes
disease, very old age, patients
of syndrome X, ischaemic and dilated
cardiomyopathy
Contraindications…
Severe aortic
regurgitation or aortic
stenosis
Deep vein thrombosis
Pregnancy
Very high blood
pressure
Severe peripheral
vascular disease
Possibility of stroke
Ischemic heart disease treatment

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Ischemic heart disease treatment

  • 1. Jeevan kishore Group – 16 4th year 2nd semester Tbilisi statemedical university ISCHEMIC HEART DISEASE TREATMENT…
  • 2. WHAT IS ISCHEMIC HEART DISEASE??? reduced blood supply to heart… by blockage in the coronary arteries or narrowing…
  • 3. CLASSIFICATION… Sudden cardiac death… Acute coronary syndrome… - Myocardial infarction and unstable angina pectoris Stable angina pectoris…
  • 5. Because it is a disease… and according to our profession, we must treat disease… It is a life threatening problem which can kill a person if left untreated and so we must treat …
  • 6. METHODS OF TREATMENT… PHARMACOLOGICAL THERAPY SURGICAL METHODS NON INVASIVE METHODS
  • 7. PHARMACOLOGICAL THERAPY… Therapy is aimed in restoring balance between myocardial oxygen supply and demand… Useful agents: Nitrates… beta-blockers … calcium channel blockers…
  • 8. NITRATES Dilates arteries to the heart and increases blood flow to the heart… Dilates veins throughout the body to hold more blood, thus reducing amount of blood going back to heart and reducing heart workload… Helps to relieve angina when used before doing some stressful activities that can cause angina… If usual dose of nitroglycerin doesn’t show relieve for angina, that means that it is becoming more worse… call a doctor immediately… Isosorbidemononitrate,dinitrate,nitroglycerine
  • 9. SIDE EFFECTS… CALL EMERGENCY SERVICES RIGHT AWAY IF YOU HAVE: Trouble breathing. Swelling of your face, lips, Tongue or throat. Hives. Blurred vision. Severe headache that does not go away. Skin rash. COMMON SIDE EFFECTS OF THIS MEDICINE INCLUDE: Dizziness or light headedness. Headache. Flushing, or feeling warm, in the face and neck. Nausea. Isosorbidemononitrate,dinitrate,nitroglycerine
  • 10. BETA-BLOCKERS Reduce workload of heart by slowing the heart rate… Help lower the blood pressure which helps to lower the risk of heart disease, heart attack and stroke… Useful for patients with heart attack to avoid future attacks… Metoprolol,carvediol,labetalol,atenolol,nebivolol
  • 11. CONTRAINDICATIONS… Symptomatic CHF… History of bronchospasm… Bradycardia or AV block… Peripheral vascular disease with s/s of claudication… Metoprolol,carvediol,labetalol,atenolol,nebivolol
  • 12. SIDE EFFECTS… CALL EMERGENCY SERVICES RIGHT AWAY IF YOU HAVE: Trouble breathing. Swelling of your face, lips, tongue, or throat. Fainting or severe dizziness. CALL YOUR DOCTOR RIGHT AWAY IF YOU HAVE: Hives. A very slow heart rate (less than 50 beats per minute). Swelling in your legs or feet. Shortness of breath. Cold hands and feet. COMMON SIDE EFFECTS OF THIS MEDICINE INCLUDE: Dizziness Feeling tired. Trouble sleeping. Metoprolol,carvediol,labetalol,atenolol,nebivolol
  • 13. CALCIUM CHANNEL BLOCKERS… Increases blood flow to the heart by dilating coronary arteries… Prevent spasm of the coronary arteries… Lower blood pressure and heart’s workload, so that heart muscle functions with less oxygen and blood flow… Controls irregular heart rhythms… Amlodipine,diltiazem,nicardipine,nifidipine, verapamil
  • 14. SIDE EFFECTS CALL EMERGENCY SERVICES RIGHT AWAY IF YOU HAVE: Trouble breathing. Swelling of your face, lips, tongue, or throat. Hives COMMON SIDE EFFECTS OF THIS MEDICINE INCLUDE: Slow heart rate. Swelling in the lower legs or ankles. Constipation or diarrhoea. Dizziness or light headedness. Flushing or feeling warm. Amlodipine,diltiazem,nicardipine,nifidipine, verapamil
  • 15. COMBINATION DRUGS… Nitrate and beta blocker Nitrate and verapamil or cardizem for similar reasons Long acting dihydropyridine calcium channel blocker and beta blocker A dihydropyridine and nitrate is often not tolerated without concomitant beta blockade because of marked vasodilatation with resultant head ache and increased heart rate
  • 17.
  • 18. ATHERECTOMY… It is alternative to angioplasty. It results in cutting of plagues from the vessels. There are 4 types of atherectomy devices :
  • 19.
  • 20. CARDIAC REHABILITATION prescribed after angina or angioplasty or cabg or heart attack… rehabilitation when recommended with surgery and medicinal treatment helps in recovery faster… it has 2 types of programme : Exercise training Educational and counselling training
  • 21. NON-INVASIVE TREATMENT • ENHANCED EXTERNAL COUNTER PULASTION IS THE NON-INVASIVE TREATMENT OF ISCHEMIA.
  • 22. The 3 pneumatic cuffs are wrapped around patient legs and connected to telemetry monitors. Telemetry monitors the heart rate and rhythm. Cuffs are wrapped on the calves, lower thighs and upper thighs or buttocks. Cuffs are timed to inflate and deflate based on patient ECG. Inflation is at the beginning of diastole. Deflation is at the beginning of systole. 1st calves are inflated then lower thighs and then upper thighs at about 200mmHg. This decreases afterload and increases the preload of heart.
  • 23. Indications… Angina patients who are not relieved by medicine Patients who don’t want to have bypass surgery Patients who are contraindicated for bypass or angioplasty due to kidney failure, liver failure, severe COPD cases, diffuse diabetes disease, very old age, patients of syndrome X, ischaemic and dilated cardiomyopathy Contraindications… Severe aortic regurgitation or aortic stenosis Deep vein thrombosis Pregnancy Very high blood pressure Severe peripheral vascular disease Possibility of stroke