Information in cinn's syndrome and it histology

1. www.mcghealth.org/.../adrenal_tumor.jpg
By: Jesse Winker
Ovall Mann
Courtney Pringle

2.  Conn’s syndrome is an Adosterone-
Producing Adenoma.
 Conn’s syndrome named after
American endocrinologist Jerome W.
Conn.
 Condition was first described at the
University of Michigan in 1955

3. urologyhealth.org

5.  Conn’s Syndrome is a disease that effects the
adrenal glands.
 It involves excess production of a hormone called
aldosterone. (which is the hormone that regulates
sodium and potassium reabsorption by the cells of
the tubular portion of the kidney.)

6.  Essential hypertension can
mimic Conn's syndrome.
 Conn’s syndrome can also be
lead to the buffalo hump
(Cushing syndrome)
 Therefore high blood pressure
and low blood potassium may
be due to essential
hypertension, which is being
treated with diuretic drugs that
cause a loss of potassium in
the urine.

7.  Conn’s syndrome normally
effect most people in their 30-
60 years of age.
 Conn’s syndrome is normally
found in female cases then
male.
 Conn syndrome occurs in 50-
60% of cases of primary
hyperaldosteronism.
image1.masterfile.com/.../82/700-
00528234w.jpg

8.  Frequent urination (polyuria)
 Increased thirst
 Weakness and fatigue
 Headache
 Muscle cramps
 Tingling in fingers
 Temporary paralysis
 Heart palpitations
 Hypertension (high blood
pressure)
adrenalstressblog.wordpress.com/

9. You can identify it
on a MRI
 The appearance of the
tumor on CAT scans
www.med-
ed.virginia.edu/.../anatomy/adrenal.html
diagnosticimaging.com

10. www.surgicaloncology.com/a
tf034c.jpg
 The goal of treatment is to
lower blood pressure.(any
other symptom)
 If tumor appears on gland
then the gland will be
removed.(laparoscopic
surgery)
 All symptoms associated
with Conn’s syndrome are
resolved and further
treatment involves
controlling blood pressure .
www.mcghealth.org/.../adrenal_tumor.jpg

11.  Most adrenal disease requiring surgery can be done using
minimally invasive (laparoscopy) surgery techniques.
Laparoscopic adrenalectomy is the preferred technique for
non-cancerous adrenal disease, including the following:
 Aldosterone-secreting adrenal tumors (Conn's syndrome)
 Cortisol-secreting adrenal tumors (Cushing's syndrome)
 Adrenalin-producing adrenal tumors (Pheochromocytoma)
 Primary adrenal hyperplasia
 Adrenal hyperplasia after failed treatment of Cushing's disease
 Large nonfunctioning adrenal tumors (<10-12cm)
 Adrenal metastasis

12. www.rfay.com.au/images/laparoscopy.jpg
 performed under a complete general anesthesia.
 A cannula (a narrow tube-like instrument) is placed
into the abdominal cavity in the upper abdomen or
flank just below the ribs.
 A laparoscope (a tiny telescope) connected to a
special camera is inserted through the cannula.
This gives the surgeon a magnified view of the
patient's internal organs on a television screen.
 Other cannulas are inserted which allow your
surgeon to delicately separate the adrenal gland
from its attachments. Once the adrenal gland has
been dissected free, it is placed in a small bag and
is then removed through one of the incisions. It is
almost always necessary to remove the entire
adrenal gland in order to safely remove the tumor.
 After the surgeon removes the adrenal gland, the
small incisions are closed.

13.  After surgery patient usually
cared for by a surgical nursing
unit.
 Usually enlisted into intensive
care to monitor he patient blood woldfitness.com
pressure.
 Patients with an aldosterone-
producing tumor will need to have
their serum potassium level
checked after surgery
 Patients cortisol-producing
tumors need to take prednisone
or cortisol
http://normalpotassiumlevels.com/meas
uring-blood-potassium-levels

14.  http://www.sages.org/publication/id/PI14/
 http://surgery.wustl.edu/Surgery_M.aspx?id=976&me
nu_id=178
 http://www.instablogsimages.com/1/2011/09/02/pills_
and_pills_kwia3.jpg
 http://emedicine.medscape.com/article/117280-
overview
 www.mcghealth.org/.../adrenal_tumor.jpg