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This ๐๐ฆ๐ฉ๐ก๐ฒ๐ฌ๐๐ฆ๐animated template is designed by RxSlides, a medical professional team covering the following topics about ๐๐ฆ๐ฉ๐ก๐ฒ๐ฌ๐๐ฆ๐
1- ๐๐๐๐ข๐ง๐ข๐ญ๐ข๐จ๐ง
โข An infection in the pleural space, causing pus accumulation.
โข A type of chronic obstructive pulmonary disease (COPD) that causes airflow blockage and breathing problems.
2- ๐ฉ๐ซ๐๐ฏ๐๐ฅ๐๐ง๐๐:
โข 4th leading cause of death in the United States
โข An estimated 16 million Americans have COPD, including ๐๐ฆ๐ฉ๐ก๐ฒ๐ฌ๐๐ฆ๐
โข More common in men than women
3- ๐๐ง๐๐ญ๐จ๐ฆ๐ฒ ๐๐ง๐ ๐ ๐ฎ๐ง๐๐ญ๐ข๐จ๐ง ๐จ๐ ๐๐ฅ๐ฏ๐๐จ๐ฅ๐ข:
โข Alveoli are the tiny air sacs in the lungs responsible for gas exchange.
โข Emphysema damages the alveoli, reducing their surface area and impacting gas exchange.
4- ๐๐๐ฌ ๐๐ฑ๐๐ก๐๐ง๐ ๐ ๐ฉ๐ซ๐จ๐๐๐ฌ๐ฌ
โข Gas exchange occurs through the process of diffusion.
โข Oxygen from the air diffuses into the blood, and carbon dioxide from the blood diffuses into the air.
โข The rate of diffusion is determined by the concentration gradient of the gases.
โข The concentration gradient of oxygen is higher in the air than in the blood, so oxygen diffuses from the air into the blood.
โข The concentration gradient of carbon dioxide is higher in the blood than in the air, so carbon dioxide diffuses from the blood into the air.
5- ๐๐๐ฎ๐ฌ๐๐ฌ:
โข Smoking
โข Pollution
โข Age
โข Alpha-1 antitrypsin (AAT) deficiency
6- ๐๐ข๐ฌ๐ค ๐ ๐๐๐ญ๐จ๐ซ๐ฌ
โข Asthma
โข Smoking
โข Chemical exposure
โข Pollution
โข Age
โข AAT deficiency
7- ๐๐๐ญ๐ก๐จ๐ฉ๐ก๐ฒ๐ฌ๐ข๐จ๐ฅ๐จ๐ ๐ฒ
โข ๐๐ฆ๐ฉ๐ก๐ฒ๐ฌ๐๐ฆ๐is caused by the destruction of the alveolar walls.
โข This destruction can be caused by several factors, including:
o Smoking:
o Alpha-1 antitrypsin deficiency:
o Exposure to air pollution:
โข Once the alveolar walls are destroyed, they cannot be repaired.
โข This leads to the formation of larger air spaces and a loss of surface area for gas exchange.
โข As a result, the lungs become less efficient at taking in oxygen and releasing carbon dioxide.
8- ๐๐ฒ๐ฆ๐ฉ๐ญ๐จ๐ฆ๐ฌ
โข Productive cough
โข Wheezing
โข Chest pain
โข Bluish fingers and lips
9- ๐๐ฒ๐ฉ๐๐ฌ
โข Panacinar
โข Centriacinar
โข Paraseptal
10- ๐๐ข๐๐ ๐ง๐จ๐ฌ๐ญ๐ข๐ ๐ฆ๐๐ญ๐ก๐จ๐๐ฌ
โข Lung function tests
โข Imaging tests
11- ๐๐ซ๐๐๐ญ๐ฆ๐๐ง๐ญ ๐๐ฉ๐ญ๐ข๐จ๐ง๐ฌ
โข Bronchodilators
โข Oxygen therapy
โข Pulmonary rehabilitation
12- ๐๐ซ๐จ๐ง๐๐ก๐จ๐๐ข๐ฅ๐๐ญ๐จ๐ซ
โข Beta-agonists: These medications work by mimicking the effects of adrenaline.
โข Anticholinergics: These medications work by blocking the effects of acetylcholine, a neurotransmitter that causes the airways to constrict
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3. Emphysema Definition
โข Definition: An
infection in the
pleural
space, causing
pus
accumulation.
โข Type of chronic
obstructive
pulmonary
disease
(COPD): Airflo
w blockage
and breathing
problems.
5. Emphysema Definition
โข An
infection in the pleural
space, causing pus
accumulation.
โข Type of
chronic obstructive
pulmonary disease
(COPD): Airflow
blockage and breathing
problems.
7. Emphysema Prevalence
โข 4th leading
cause of death in the
United States
โข Estimated
16 million Americans
have COPD, including
emphysema
8. Anatomy and Function of Alveoli
โข The
alveoli are the basic
units of gas exchange
in the lungs.
โข They are
tiny, balloon-like
structures that are
surrounded by a
network of capillaries.
โข The
alveoli are filled with
air, and the capillaries
are filled with blood.
โข Gas
exchange occurs
through the walls of the
alveoli and the
capillaries.
โข Oxygen
from the air diffuses
into the blood, and
carbon dioxide from
the blood diffuses into
the air.
9. Gas exchange process
โข Gas exchange occurs
through the process of
diffusion.
โข Oxygen from the air
diffuses into the blood,
and carbon dioxide from
the blood diffuses into
the air.
โข The rate of diffusion is
determined by the
concentration gradient
of the gases.
โข The concentration
gradient of oxygen is
higher in the air than in
the blood, so oxygen
diffuses from the air into
the blood.
โข The concentration
gradient of carbon
dioxide is higher in the
blood than in the air, so
carbon dioxide diffuses
from the blood into the
air.
10. Normal and abnormal respiration
โข In emphysema,
the alveoli are
damaged, which
makes it difficult
for them to
expand and
contract.
โข This leads to air
trapping and
hyperinflation of
the lungs.
โข As a result, gas
exchange is
impaired, and the
body does not
receive enough
oxygen.
11. Emphysema Causes
โข
Smoki
ng: The leading
cause, of damaging
alveoli over time.
โข
Polluti
on: Exposure to air
pollutants irritates
and inflames lung
tissues.
โข Age:
Natural decline in
lung function
increases
susceptibility.
โข Alpha-
1 Antitrypsin (AAT)
Deficiency: Genetic
condition leading to
enzyme deficiency
and emphysema
development.
12. Emphysema Risk factors
โข Asthma: Pre-existing
condition can worsen
emphysema
symptoms.
โข Smoking: Synergistic
effect with other risk
factors.
โข Chemical
Exposure: Occupatio
nal exposure to
irritants can damage
lung tissues.
โข Pollution: Increases
risk, especially in
high-pollution
environments.
โข Age: Ageing lungs
are more susceptible
to damage and
emphysema
development.
โข AAT
Deficiency: Genetic
predisposition
significantly increases
risk.
13. Emphysema Pathogenesis
โข Emphysema is caused
by the destruction of
the alveolar walls.
โข This destruction can be
caused by several
factors, including:
o Smoking:
o Alpha-1
antitrypsin
deficiency:
o Exposure to air
pollution:
14. Emphysema Pathogenesis
โข Once the alveolar
walls are destroyed,
they cannot be
repaired.
โข This leads to the
formation of larger
air spaces and a
loss of surface area
for gas exchange.
โข As a result, the
lungs become less
efficient at taking in
oxygen and
releasing carbon
dioxide.
15. Emphysema Symptoms
โข
Productiv
e cough (with phlegm)
โข Wheezing
and shortness of breath
โข Chest
pain or tightness
โข Bluish
discoloration of fingers
and lips (cyanosis)
16. Emphysema Types
โข Panacinar: Unifor
m destruction of
alveoli
throughout all
lung lobes.
โข Centriacinar: Da
mage primarily
affects the
central regions of
the lung.
โข Paraseptal: Alve
olar destruction
starts near the
walls of the
airways.
18. Bronchodilators
โข
Bronchod
ilators are medications
that relax the smooth
muscles in the airways.
โข This
helps to open the
airways and make it
easier for air to flow in
and out of the lungs.
โข
Bronchod
ilators are commonly
used to treat
emphysema and other
COPD symptoms.
19. Bronchodilators
โข There are two main
types of
bronchodilators:
o Beta-
agonists:
These
medications
work by
mimicking the
effects of
adrenaline.
o Anticholinergi
cs: These
medications
work by
blocking the
effects of
acetylcholine,
a
neurotransmit
ter that
causes the
airways to
constrict.
22. Emphysema Prevention
โข Smoking
cessation: The most
effective prevention
measure.
โข Immunizations: Vac
cination against
respiratory
infections.
โข Regular
monitoring: Early
detection and
management of
symptoms.
โข Physical
activity: Improves
lung function and
overall health.