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Biotest Overview March 2009
- 1. Biotest Blood Bank Solutions March 5 th , 2009
- 16. Results of Rh Antisera Evaluation Biotest Significantly Outperforms 61 4 96 Anti-e 108 110 110 97 Number of samples tested Roughly Equivalent 10 14 Anti-c Roughly Equivalent 5 3 Anti-E Roughly Equivalent 29 14 Anti-C Roughly Equivalent 18 14 Anti-D Blend Conclusion # Stronger with Biotest Rgts # Stronger with Reference Rgts Antisera
- 17. Rare Antisera Evaluation Biotest Outperforms 17 2 31 Anti-s Biotest Outperforms 10 0 31 Anti-S Roughly Equivalent 6 2 30 Anti-N Roughly Equivalent 0 1 11 Anti-k Equivalent 0 0 41 Anti-K Conclusion # Stronger with Biotest Rgts # Stronger with Reference Rgts # Samples tested Antisera
- 18. Rare Antisera Evaluation Roughly Equivalent 4 0 30 Anti-Lea Biotest Outperforms 10 0 18 Anti-P1 Roughly Equivalent 2 2 31 Anti-Jkb Roughly Equivalent 3 8 31 Anti-Jka Biotest Outperforms 11 0 31 Anti-Fya Conclusion # Stronger with Biotest Rgts # Stronger with Reference Rgts # Samples tested Antisera
- 34. Solidscreen II Reaction Patterns Positive Antibody Screen Negative Antibody Screen
- 35. Field Trial Sensitivity by Method
- 38. Comparison of Solid-Phase Antibody Screening Tests with Pooled Red Cells in Blood Donors Reference: Vox Sang 1996;71:37-42 Solid-phase antibody screening in 10,008 blood donors Technique number of Detection of donors with donors detected IgG Antibodies (n=41) IgG a nonspecific b sensitivity specificity test % % efficiency c Capture R Ready Screen 40 61 97.6 99.39 1.40 Solidscreen II (polyspecific AHG) 39 11 95.1 99.88 1.89 Solidscreen II – (Anti-IgG) 38 2 92.7 99.98 1.95 Total d 41 67 a Correct positive test result: IgG antibody with blood group specificity detected. b False-positive test result: nonspecific positive reactions with all panel cells including the autocontrol. c The test efficiency (result validity) is the sum of the predictive values for positive and negative test results. A value of 2.0 indicates an optimal test efficiency.
- 46. It's time to