3rd Year MBBS By Dr. Yasir Shabbir Gujranwala Medical College Gujranwala

1. EMBOLISM
BY
DR. YASIR SHABBIR
PATHOLOGY DEPARTMENT

2. EMBOLISM
Detached Intra Vascular solid liquid or
Gaseous Mass
• Cholestrol Embies
• Termbo Embolish

3. TYPES
• Pulmonay
• Systemetic
• Fat
• Marrow
• Air
• Aminiotic

4. PULMONARY EMBOLISM
•2-4/1000 USA
•1,00000/ per year USA
•95% DVT

5. SADDLE THROMBUS
• Pulmonary Artery
• High Risk for pulmonary Embolism

6. PARADOXICAL EMBOLISM
• Inter Arterial Defect
• Inter Septal effect

7. COR PULMONALE
• Pulmonary Artery – End Arteriole Haemhrriage Infaction
• Multiple Embolies Pulmonary Hyper tension
• Right Heart Failure

8. SYSTEMIC
THROMBOEMBOLISM
• Intracardial Mural Thrombies 80%
• Aortic Aneurysm
• Atherosclerotic Plaque
• Valvular Vagetation
I. Caliber of Blood Vessel
II. Colletral Blood Supply

9. FAT EMBOLISM
• Fracture
• Soft Tissue Trauma
• Burns
• Cardio Pulmonary Resuscitation
• Skeletal Muscles Injuries

10. PATHOGENESIS OF FAT EMBOLISM
• Mechanical obstruction Biochemical Injury
• Red Cell Aggregation Anemia
• Platelet Aggregation Thrombocytopenia
• Protease, Eicosanoids, Free Fatty Acid
• Toxic Injury Endothelium

11. CLINICAL FEATURES OF FAT EMBOLISM
• Anemia
• Thrombocyopenia
• Delirum
• COMA
• Death

12. AIR EMBOLISM
• Frothy Mass in circulation
• Bypass surgery
• Neuro Surgery in sitting position
• Obstetric Laparoscopic Surgery
• Bends GRECIAN Bend Fashion Pose

13. • Edema
• Haemhrrage
• Focal Atelactassis
• Emphysema
• Cassion Diease
• High Pressure Gass
• Cuba Sea Divers
• Under Water constructor

14. AMNIOTIC EMBOLISM
• 5th world wide
• 10% of Materna Death
• Rupture of Membrane Uterine Veins
• Labour Post Partum

15. AUTOPSY FINDINGS
I. Sqamous Cells Shed from FETUS skin
II.Lanugo Hair
III.Fat from the Vernix Ceaseosa
IV.Mucin from the Respiratory or GIT System
V.Pulmonary Edema
VI.Diffuse Alveolar Damage

16. CLINICAL FEATURES