Suppose a mutation occurs in the gene encoding eukaryotic RNA polymerase I, II, or III that renders that polymerase non-functional. Match each RNA polymerase mutation with all of the cellular processes that it would disrupt. Solution Mutation in RNA polymerase 1 mutation in RNA polymerase II mutation in rna Polymerase III mRNA translation. rRNA synthesis. Pre mRNA processing. Pre mRNA synthesis. RNAi mediated gene regulation. rRNA processing. RNAi mediated gene regulation. mRNA translation. rRNA synthesis. tRNA synthesis.. Pre mRNA processing..