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CASE STUD A patient aged 47 years came to the clinic after minor work accident. He worked
as a painter. and he had fallen off a 12-foot scaffold and hurt his ankle. He had a complicated
medical history that ed severe diabetes, diagnosed a decade earlier, with peripheral neuropathy
and retinopathy; chronic renal insufficiency; hypertension for the past 20 years; and
hyperlipidemia. At this clinic visit, the patient was noted to have mild hepatomegaly. The
patient's blood showed a normochromic normocytic anemia. An SPE with immunofixation
demonstrated a monoclonal IgGK of less than 100 mg/dL. An Pro urine protein electrophoresis
(UPE) with immuno- fixation was negative for light chains (Bence Jones protein). Although his
ankle was not sprained, the vag patient continued to have breathing problems over bec the next
several months and returned to the clinic and often. Among many other tests, a follow-up SPE
and qua an UPE with immunofixation were performed. The usin results are shown below. the
kno to a Control Patient Control Patient alte low shad Band of p Application of da blad that
Solution
serum protein electrophoresis (SPE) - IgGk-100mg/dl.
darker( G -) IgG and lighter IgA and absense of M indicates normal level but there are
monoclonal antibodies indicates (kappa)
1) A patient with myeloma
2) We can characterize with immunofixation
3) No it is not consistant
4) Monoclonal Gummopathy of Undetermined Significance---An abnormal protien in blood (m
protien) with no problems of importance

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CASE STUD A patient aged 47 years came to the clinic after minor work.pdf

  • 1. CASE STUD A patient aged 47 years came to the clinic after minor work accident. He worked as a painter. and he had fallen off a 12-foot scaffold and hurt his ankle. He had a complicated medical history that ed severe diabetes, diagnosed a decade earlier, with peripheral neuropathy and retinopathy; chronic renal insufficiency; hypertension for the past 20 years; and hyperlipidemia. At this clinic visit, the patient was noted to have mild hepatomegaly. The patient's blood showed a normochromic normocytic anemia. An SPE with immunofixation demonstrated a monoclonal IgGK of less than 100 mg/dL. An Pro urine protein electrophoresis (UPE) with immuno- fixation was negative for light chains (Bence Jones protein). Although his ankle was not sprained, the vag patient continued to have breathing problems over bec the next several months and returned to the clinic and often. Among many other tests, a follow-up SPE and qua an UPE with immunofixation were performed. The usin results are shown below. the kno to a Control Patient Control Patient alte low shad Band of p Application of da blad that Solution serum protein electrophoresis (SPE) - IgGk-100mg/dl. darker( G -) IgG and lighter IgA and absense of M indicates normal level but there are monoclonal antibodies indicates (kappa) 1) A patient with myeloma 2) We can characterize with immunofixation 3) No it is not consistant 4) Monoclonal Gummopathy of Undetermined Significance---An abnormal protien in blood (m protien) with no problems of importance