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Thoracis anaesthesia
zikrullah
• Thoracis surgery presents with
what unique set of physiologic
problems??
THORACIC ANAESTHESIA
• 1)Lateral decubitus position
2)The open pneumothorax
3)One lung ventilation
• What happens to lung mechanics during
lateral decubitus position?
• Awake state?
• After induction of anesthesia?
AWAKE STATE:
V/Q: Preserved
Dependent lung:
More perfused
Receives more ventilation
Contraction of hemidiaphragm more
efficient
More favourable part of compliance curve
• V/Q : mismatch and hypoxia
• Induction of G.A: FRC & moves lower
lung( perfused) to less compliant part of
the compliance curve
• PPV favors the upper lung (Compliant)
• Neuromuscular blockade: abdominal
contents rise up against dependent
hemidiaphragm
• Rigid bean bag
INDUCTION AND PPV
What happens during open
pneumothorax?
. The Open Pneumothorax :
• The lungs are kept expanded by the
negative pleural pressure .When chest is
opened the –ve pleural pressure is lost
and the lung is collapsed
• Spontaneous ventilation with open
pneumothorax in the lateral position
results in paradoxical respiration &
mediastinal shift
Paradoxical respiration:
• During spont ventilation
• To and fro gas flow between dependent
and non dependent lung
Mediastinal shift:
• During spont ventilation
• Downward shift of mediastinum during
inspiration
• Upward shift during expiration
• Concerns during one lung
ventilation?
3. One Lung Ventilation:
• Intentional collapse of the lung on the
operative side greatly facilitates most
thoracic procedures but complicates
anesthetic management
• The collapsed lung continues to be perfused
and no longer ventilated
• So the patient develops RT to LT
intrapulmonary shunt hypoxia
• Widens alveolar to arterial gradient
hypoxia
• Protective mechanism?
Hypoxic pulmonary vasoconstriction
Factors inhibiting:
• Pulmonary artery pressure: very high or
low
• Hypocapnia
• Mixed venous oxygen : very high or low
• Vasodilators
• Pulmonary infection
• Inhalational anesthetic
• Technique of one lung
ventilation?
• Techniques for one lung ventilation:
1. Use of double lumen BT
2. Use of single lumen ET + bronchial blocker
3. Use of single lumen EBT
• Double lumen endobronchial tube is often
used
Indication of lung ventilation?
• Indications for one lung ventilation:
-CONFINED INFECTION TO ONE LUNG
-CONFINED BLEEDING TO ONE LUNG
-SEPARATE LUNG VENTILATION:
*large cyst or bulla *BPF *tracheobron. disruption
PATIENT
RELATED:
-LUNG RESECTION:
*pneumonectomy *lobectomy *segmental resection
-THORACOSCOPY
-ANT. APPROACH TO THORACIC SPINE
-ESOPHAGEAL SURGERY -B.A. LAVAGE
PROCEDURE
RELATED:
Absolute indication for OLV
– Isolation of one lung from the other to avoid
spillage or contamination
• Infection
• Massive hemorrhage
– Control of the distribution of ventilation
• Bronchopleural / - cutaneous fistula
• Surgical opening of a major conducting airway
• giant unilateral lung cyst or bulla
• Tracheobronchial tree disruption
• Life-threatening hypoxemia due to unilateral lung
disease
– Unilateral bronchopulmonary lavage
– VAT
Relative indication
– Surgical exposure ( high priority)
• Thoracic aortic aneurysm
• Pneumonectomy
• Upper lobectomy
• Mediastinal exposure
• Thoracoscopy
– Surgical exposure (Intermediate priority)
• Middle and lower lobectomies and subsegmental
resections
• Esophageal surgery
• Thoracic spine procedure
• Minimal invasive cardiac surgery .
• Postcardiopulmonary bypass status after
removal of totally occluding chronic unilateral
pulmonary emboli (Low priority)
• Types of DLT?
• Advantage/disadvantage?
THORACIC ANESTHESIA
• Double lumen endobronchial tubes:
Carinal hookBronchusName
YESLEFTCARLENS
NOLEFT -RIGHTROBERT-SHAW
YESRIGHTWHITE
• Advantage:
– Can suction lungs independently
– Quality of suctioning better
– Can apply CPAP to nonventilated lung
• Disadvantage:
– Difficult to insert.
– Needs change of tube if postoperative
ventilation is considered
– Needs determination of appropriate size
– Potential for tracheobronchial injury
How is the size of the DLT
determined for each patient?
• An ideally placed DLT should pass easily
through the glottis and should enter the
intended main bronchus without causing
trauma
• Single-use PVC DLTs : 26 F, 28 F, 32 F,
35 F, 37 F, 39 F, 41 F
• 35 F and 37 F - small and large females
• 39 F and 41 F for small and large males
Why are left sided DLTs
preferred over right?
• The right upper lobe bronchus takes off
from the right main bronchus 0.5 to 1 cm
below the carina
• When right sided DLT is placed, there
are high chances that the right upper
lobe bronchus may be occluded
• Left mainstem bronchus is much longer
than the right one (50 mm as compared
to 20 mm)
• Margin of safety while positioning a left
sided DLT is more
Describe the pre-anaesthetic
evaluation of a patient posted
for lung resection surgery ?
• ƒDetailed medical history : coexisting disease
• Optimal treatment and control of associated
medical conditions
• Patient’s functional capacity should be assessed
• History of smoking, symptoms suggestive of COPD
elicited
• Preoperative cardiologic evaluation
• Airway evaluation
• Patients may receive chemotherapy
preoperatively, and should be evaluated for
chemotherapy related toxicity
Investigations?
Investigations
• CBC : Polycythemia - COPD or leucocytosis -
active pulmonary infection
• Sputum cultures and sensitivity to guide
appropriate antibiotic therapy
• Renal function test
• Liver function test
• X-ray Chest : tracheal deviation or
obstruction, mediastinal mass, superior vena
cava syndrome, pleural effusions,
consolidation
• Pulmonary function tests : obstructive or
restrictive abnormalities, to assess
responsiveness to bronchodilators and to
confirm suitability for resection
• ECG : For signs of left or right heart
dysfunction
• TTE : to rule out pulmonary hypertension
• Further cardiopulmonary testing may be
indicate if warranted by the history/above
investigations
Describe the 3 legged stool
test of prethoracotomy
respiratory assessment ?
Predicted post operative FEV1?
Importance?
Preoperative optimization?
THORACIC ANESTHESIA
• Preoperative management
ResultMeasures
HbCO2 decreases in 12-24h
so more O2 is available
Cessation of smoking
Select antibiotics according
to culture and sensitivity
Treat pulmonary infections
Beta-2 agonistsTreat bronchospasm
Hydration and chest
percussion
Thin and mobilize secretions
Preparation?
Monitoring?
THORACIC ANESTHESIA
1) Preparation:
• Apart from basic airway management
• Multiple single and double tubes should be
available
• fiberoptic bronchoscope should be available
• Tube exchanger
• Cpap delivery system,bronchodilator
• Thoracic epidural catheter
THORACIC ANESTHESIA
2) Venous access:
• At least 2 large iv canula( 14-16 g) is
mandatory
• CV catheter, blood warmer ,rapid infusion
device are desired if blood loss is
anticipated
3) Monitoring:
• ECG
• pulse oximetry
• Capnography
• NIBP
• Temperature
• Urinary catheterization
• Arterial cannula
• CVP monitoring
• PAC is indicated in LT ventricle dysfunction
• Periodic ABG
Induction?
Maintenance?
• GA with controlled ventilation with
thoracic epidural analgesia
• IV induction with propofol or
thiopentone
• Propofol : preferred since many of these
patients will have reactive airways and
use of thiopentone and tracheal
instrumentation in light plane can lead to
bronchospasm
• NDMR can be used
• Maintenance : halogenated agent + opiod
• Delivered in an oxygen/air or
oxygen/nitrous oxide mix
• During one-lung ventilation, anaesthesia
can be maintained intravenously with
propofol and an air/oxygen mix
What is management of
hypoxemia during one lung
ventilation?
• For sudden or severe desaturation:
–Convert to two-lung ventilation
• For gradual desaturation:
1. Increase FiO2 to 1.0
2. The position of DLT should be
rechecked using a fiberoptic
bronchoscope.
3. The hemodynamic status of the patient
should be optimized
4. Recruitment of the ventilated lung
5. PEEP of 5-10 cm H2O: the dependent
lung
6. CPAP of 1-2 cm H2O: to the
nondependent lung, after a recruitment
maneuver
7. Intermittent two-lung ventilation.
8. Partial ventilation of the non-ventilated
lung using either low flow oxygen
insufflations or high frequency ventilation
9. If a pneumonectomy is being
performed, ligation of the pulmonary
artery : completely eliminate the shunt.
Fluid management in these
patients?
• Fluid restriction is generally advocated in lung
resections.
• The reasons for this are:
– Third spacing is not excessive in lung surgeries
– The dependent lung : high capillary hydrostatic
pressures
– Postoperative pulmonary edema
– Surgery may impair lymphatic drainage. It is
recommended that the total positive fluid
balance in the first 24 hours should not
exceed 20 mL/kg
Lower lung syndrome?
• Excessive fluid administration may
promote this syndrome i.e gravity
dependent transudation of fluid into the
dependent lung
What about mechanical
ventilation post op?
• Most patients are extubated early to
reduce the risk of pulmonary
barotrauma, blowout of the bronchial
stump and pulmonary infection
• Pts with marginal reserve: Double lumen
tube is exchanged with regular
tube,extubated when criteria met
What are the available
techniques for pain relief in
this patient?
• Thoracic epidural analgesia:gold standard for
post-thoracotomy analgesia
– The epidural is most effective when placed at
the vertebral level corresponding with the
dermatomes of the surgical incision.
– Local anaesthetic solutions may be infused
continuously or via a patient controlled device
– Opiods can be added
• Parenteral opioids: Patient-controlled analgesia
(PCA) devices can be used to deliver opioids
• Paravertebral blocks
• Intrathecal opioids
• Intercostal nerve blocks
Post-op complications of
pneumonectomy?
• 1. Cardiovascular:
– a. Arrhythmias
– b. Right ventricular failure
– c. Cardiac herniation
– d. Hemorrhage
• 2. Pulmonary
– a. Pulmonary edema
– b. Respiratory insufficiency
– c. Pulmonary torsion
• 3. Pneumonectomy space
– a. Bronchopleural fistula
– b. Empyema
• 4. Neurological
– Recurrent laryngeal, vagus or phrenic nerve injury
Indication of thoracotomy
once ICTD is placed?
• > 1.5 L once ICTD is placed.
• > 200ml/hr for consecutive 4 hrs
• Clotted hemothorax
• Persistent pneumothorax
What are the indications
of chest tube insertion
• Asymptomatic patients with minimal
pneumothorax (< 15–20% of hemithorax) :
conservative management
• Symptomatic or patients with larger
pneumothorax need aspiration or drainage
• ICTD indications :
1. Pneumothorax
a. In mechanically ventilated patient
b. Tension pneumothorax after initial
decompression by inserting a needle
c. Persistent or recurrent pneumothorax
after simple aspiration
2. Large or symptomatic pleural
effusions
3. Other pleural collections
a. Pus (empyema)
b. Blood (hemothorax)
c. Chyle (chylothorax)
4. Postoperative—after thoracotomy
or thoracoscopy

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Thoracic surgery anesthesia

  • 2. • Thoracis surgery presents with what unique set of physiologic problems??
  • 3. THORACIC ANAESTHESIA • 1)Lateral decubitus position 2)The open pneumothorax 3)One lung ventilation
  • 4. • What happens to lung mechanics during lateral decubitus position? • Awake state? • After induction of anesthesia?
  • 5.
  • 6. AWAKE STATE: V/Q: Preserved Dependent lung: More perfused Receives more ventilation Contraction of hemidiaphragm more efficient More favourable part of compliance curve
  • 7. • V/Q : mismatch and hypoxia • Induction of G.A: FRC & moves lower lung( perfused) to less compliant part of the compliance curve • PPV favors the upper lung (Compliant) • Neuromuscular blockade: abdominal contents rise up against dependent hemidiaphragm • Rigid bean bag INDUCTION AND PPV
  • 8. What happens during open pneumothorax?
  • 9. . The Open Pneumothorax : • The lungs are kept expanded by the negative pleural pressure .When chest is opened the –ve pleural pressure is lost and the lung is collapsed • Spontaneous ventilation with open pneumothorax in the lateral position results in paradoxical respiration & mediastinal shift
  • 10. Paradoxical respiration: • During spont ventilation • To and fro gas flow between dependent and non dependent lung
  • 11.
  • 12. Mediastinal shift: • During spont ventilation • Downward shift of mediastinum during inspiration • Upward shift during expiration
  • 13.
  • 14. • Concerns during one lung ventilation?
  • 15. 3. One Lung Ventilation: • Intentional collapse of the lung on the operative side greatly facilitates most thoracic procedures but complicates anesthetic management • The collapsed lung continues to be perfused and no longer ventilated
  • 16. • So the patient develops RT to LT intrapulmonary shunt hypoxia • Widens alveolar to arterial gradient hypoxia
  • 18. Hypoxic pulmonary vasoconstriction Factors inhibiting: • Pulmonary artery pressure: very high or low • Hypocapnia • Mixed venous oxygen : very high or low • Vasodilators • Pulmonary infection • Inhalational anesthetic
  • 19. • Technique of one lung ventilation?
  • 20. • Techniques for one lung ventilation: 1. Use of double lumen BT 2. Use of single lumen ET + bronchial blocker 3. Use of single lumen EBT • Double lumen endobronchial tube is often used
  • 21. Indication of lung ventilation?
  • 22. • Indications for one lung ventilation: -CONFINED INFECTION TO ONE LUNG -CONFINED BLEEDING TO ONE LUNG -SEPARATE LUNG VENTILATION: *large cyst or bulla *BPF *tracheobron. disruption PATIENT RELATED: -LUNG RESECTION: *pneumonectomy *lobectomy *segmental resection -THORACOSCOPY -ANT. APPROACH TO THORACIC SPINE -ESOPHAGEAL SURGERY -B.A. LAVAGE PROCEDURE RELATED:
  • 23. Absolute indication for OLV – Isolation of one lung from the other to avoid spillage or contamination • Infection • Massive hemorrhage – Control of the distribution of ventilation • Bronchopleural / - cutaneous fistula • Surgical opening of a major conducting airway • giant unilateral lung cyst or bulla • Tracheobronchial tree disruption • Life-threatening hypoxemia due to unilateral lung disease
  • 25. Relative indication – Surgical exposure ( high priority) • Thoracic aortic aneurysm • Pneumonectomy • Upper lobectomy • Mediastinal exposure • Thoracoscopy – Surgical exposure (Intermediate priority) • Middle and lower lobectomies and subsegmental resections • Esophageal surgery • Thoracic spine procedure • Minimal invasive cardiac surgery .
  • 26. • Postcardiopulmonary bypass status after removal of totally occluding chronic unilateral pulmonary emboli (Low priority)
  • 27. • Types of DLT? • Advantage/disadvantage?
  • 28. THORACIC ANESTHESIA • Double lumen endobronchial tubes: Carinal hookBronchusName YESLEFTCARLENS NOLEFT -RIGHTROBERT-SHAW YESRIGHTWHITE
  • 29. • Advantage: – Can suction lungs independently – Quality of suctioning better – Can apply CPAP to nonventilated lung • Disadvantage: – Difficult to insert. – Needs change of tube if postoperative ventilation is considered – Needs determination of appropriate size – Potential for tracheobronchial injury
  • 30. How is the size of the DLT determined for each patient?
  • 31. • An ideally placed DLT should pass easily through the glottis and should enter the intended main bronchus without causing trauma • Single-use PVC DLTs : 26 F, 28 F, 32 F, 35 F, 37 F, 39 F, 41 F • 35 F and 37 F - small and large females • 39 F and 41 F for small and large males
  • 32.
  • 33. Why are left sided DLTs preferred over right?
  • 34. • The right upper lobe bronchus takes off from the right main bronchus 0.5 to 1 cm below the carina • When right sided DLT is placed, there are high chances that the right upper lobe bronchus may be occluded • Left mainstem bronchus is much longer than the right one (50 mm as compared to 20 mm) • Margin of safety while positioning a left sided DLT is more
  • 35.
  • 36. Describe the pre-anaesthetic evaluation of a patient posted for lung resection surgery ?
  • 37. • ƒDetailed medical history : coexisting disease • Optimal treatment and control of associated medical conditions • Patient’s functional capacity should be assessed • History of smoking, symptoms suggestive of COPD elicited • Preoperative cardiologic evaluation • Airway evaluation • Patients may receive chemotherapy preoperatively, and should be evaluated for chemotherapy related toxicity
  • 39. Investigations • CBC : Polycythemia - COPD or leucocytosis - active pulmonary infection • Sputum cultures and sensitivity to guide appropriate antibiotic therapy • Renal function test • Liver function test • X-ray Chest : tracheal deviation or obstruction, mediastinal mass, superior vena cava syndrome, pleural effusions, consolidation
  • 40. • Pulmonary function tests : obstructive or restrictive abnormalities, to assess responsiveness to bronchodilators and to confirm suitability for resection • ECG : For signs of left or right heart dysfunction • TTE : to rule out pulmonary hypertension • Further cardiopulmonary testing may be indicate if warranted by the history/above investigations
  • 41. Describe the 3 legged stool test of prethoracotomy respiratory assessment ?
  • 42.
  • 43. Predicted post operative FEV1? Importance?
  • 44.
  • 46. THORACIC ANESTHESIA • Preoperative management ResultMeasures HbCO2 decreases in 12-24h so more O2 is available Cessation of smoking Select antibiotics according to culture and sensitivity Treat pulmonary infections Beta-2 agonistsTreat bronchospasm Hydration and chest percussion Thin and mobilize secretions
  • 48. THORACIC ANESTHESIA 1) Preparation: • Apart from basic airway management • Multiple single and double tubes should be available • fiberoptic bronchoscope should be available • Tube exchanger • Cpap delivery system,bronchodilator • Thoracic epidural catheter
  • 49. THORACIC ANESTHESIA 2) Venous access: • At least 2 large iv canula( 14-16 g) is mandatory • CV catheter, blood warmer ,rapid infusion device are desired if blood loss is anticipated
  • 50. 3) Monitoring: • ECG • pulse oximetry • Capnography • NIBP • Temperature • Urinary catheterization • Arterial cannula • CVP monitoring • PAC is indicated in LT ventricle dysfunction • Periodic ABG
  • 52. • GA with controlled ventilation with thoracic epidural analgesia • IV induction with propofol or thiopentone • Propofol : preferred since many of these patients will have reactive airways and use of thiopentone and tracheal instrumentation in light plane can lead to bronchospasm • NDMR can be used
  • 53. • Maintenance : halogenated agent + opiod • Delivered in an oxygen/air or oxygen/nitrous oxide mix • During one-lung ventilation, anaesthesia can be maintained intravenously with propofol and an air/oxygen mix
  • 54. What is management of hypoxemia during one lung ventilation?
  • 55. • For sudden or severe desaturation: –Convert to two-lung ventilation • For gradual desaturation: 1. Increase FiO2 to 1.0 2. The position of DLT should be rechecked using a fiberoptic bronchoscope. 3. The hemodynamic status of the patient should be optimized 4. Recruitment of the ventilated lung
  • 56. 5. PEEP of 5-10 cm H2O: the dependent lung 6. CPAP of 1-2 cm H2O: to the nondependent lung, after a recruitment maneuver 7. Intermittent two-lung ventilation. 8. Partial ventilation of the non-ventilated lung using either low flow oxygen insufflations or high frequency ventilation 9. If a pneumonectomy is being performed, ligation of the pulmonary artery : completely eliminate the shunt.
  • 57. Fluid management in these patients?
  • 58. • Fluid restriction is generally advocated in lung resections. • The reasons for this are: – Third spacing is not excessive in lung surgeries – The dependent lung : high capillary hydrostatic pressures – Postoperative pulmonary edema – Surgery may impair lymphatic drainage. It is recommended that the total positive fluid balance in the first 24 hours should not exceed 20 mL/kg
  • 60. • Excessive fluid administration may promote this syndrome i.e gravity dependent transudation of fluid into the dependent lung
  • 62. • Most patients are extubated early to reduce the risk of pulmonary barotrauma, blowout of the bronchial stump and pulmonary infection • Pts with marginal reserve: Double lumen tube is exchanged with regular tube,extubated when criteria met
  • 63. What are the available techniques for pain relief in this patient?
  • 64. • Thoracic epidural analgesia:gold standard for post-thoracotomy analgesia – The epidural is most effective when placed at the vertebral level corresponding with the dermatomes of the surgical incision. – Local anaesthetic solutions may be infused continuously or via a patient controlled device – Opiods can be added • Parenteral opioids: Patient-controlled analgesia (PCA) devices can be used to deliver opioids
  • 65. • Paravertebral blocks • Intrathecal opioids • Intercostal nerve blocks
  • 67. • 1. Cardiovascular: – a. Arrhythmias – b. Right ventricular failure – c. Cardiac herniation – d. Hemorrhage • 2. Pulmonary – a. Pulmonary edema – b. Respiratory insufficiency – c. Pulmonary torsion • 3. Pneumonectomy space – a. Bronchopleural fistula – b. Empyema • 4. Neurological – Recurrent laryngeal, vagus or phrenic nerve injury
  • 69. • > 1.5 L once ICTD is placed. • > 200ml/hr for consecutive 4 hrs • Clotted hemothorax • Persistent pneumothorax
  • 70. What are the indications of chest tube insertion
  • 71. • Asymptomatic patients with minimal pneumothorax (< 15–20% of hemithorax) : conservative management • Symptomatic or patients with larger pneumothorax need aspiration or drainage • ICTD indications : 1. Pneumothorax a. In mechanically ventilated patient b. Tension pneumothorax after initial decompression by inserting a needle c. Persistent or recurrent pneumothorax after simple aspiration
  • 72. 2. Large or symptomatic pleural effusions 3. Other pleural collections a. Pus (empyema) b. Blood (hemothorax) c. Chyle (chylothorax) 4. Postoperative—after thoracotomy or thoracoscopy