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Daibetes Mellitus
Presented By
Yasin Rahman!
DIABETES MELLITUS
Definitions
•A disease marked by high levels of
sugar in blood.
 OR
•A chronic metabolic disorder
characterized by persistent high
blood glucose concentration.
Word Mellitus Meaning
•Mellitus A Latin word
for" Sweet As Honey"
Causes:
Insulin deficiency or insulin
resistance
INSULIN
Beta cells of
islets of
langerhans
produce insulin
which is
needed for to
metabolize
glucose within
the body.
Cardinal Signs of
Diabetes Mellitus
•Polyuria(abnormally large
volume of urine)
•Polydispia(excessive thirst)
•Polyphagia(excessive
hunger)
Types of Diabetes
Mellitus
There Are Two Types Of DM,
 Type 1DM
 Type 2DM
Type1DM
Definition:
Type1DM develops if
, the body is unable to produce
any insulin..
Type2 DM
Definition:
Type2DM develops when
body can still make some insulin but
not enough or when insulin that is
produced does not work properly
(known as insulin resistance)
Prevalance of Type1DM
 It usually appears before
the age of 40
 It accounts for between 5-
15% of all diabetic people
Prevalance of
Type2DM
 It is linked with being
over weight
 It appears over the age of 40
 It accounts for between 85-
95%
all people with diabetes
• Genetic
• Autoimmune
• Childhood (
juvenile) onset
• Beta cells depletion
• Non-Obese
patients
• Genetic but different
from Type1DM
• Not autoimmune
• Adult , maturity
onset
• Insulin may be low
but resistance to
insulin is main factor
• Non-Obese patients
Differences Between
Type1DM And Type2DM
Signs And Symptoms Of
Type2DM
•Slower onset
•Increased thirst
•Increased urination
•Increased apptite
•Fatigue
•Blured vision
•Slow healing infections
Risk Factors:
Family History
Obesity
Age greater than 45 years
Some ethnic groups
High BP
High cholesterol level
Physical inactivity
Metabolic
Complications
Hyperglycemia is caused by
eating too much sugary food /
drinking alcohol ,, not
complying with insulin therapy
or no exercise ,
• High blood glucose can lead to
Diabetic ketoacidosis/DKA/
Diabetic Coma which is caused
by the build up of by products of
fat break down known as
ketones,
•Occurs when glucose is not
available as a fuel source for
the body and fat is used ,
instead.
Symptoms Of DKA:
•Polyuria
•Polydispia
•Fatigue
•Nausea
•Muscular stiffness or aching
• Mental stupor( decreased consciousness)
may progress to Coma
• Rapid breathing
• Fruity breath
• Headache
• Decreased BP
• Decreased appetite
• Abdominal pain
Diabetic Complications
Diabetes can cause
vascular system
complications,,, which are
of two types
•Macrovascular
•Microvascular
•Stroke
•Cardiovascular diseases
•Peripheral vascular
diseases(amputation)
Macrovascular
complications
Microvascular
Complications
•Diabetic nephropathy(leads to
chronic kidney failure)
•Diabetic retinopathy
•Diabetic neuropathy (loss of
sensation in toes, numbness)
Thanks

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Diabetes millatus