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Jeffrey P. Jacobs, M.D., FACS, FACC, FCCP
Professor of Surgery and Pediatrics, Johns Hopkins University
Co-Director, Johns Hopkins All Children’s Heart Institute
Chief, Division of Cardiovascular Surgery
Director, Andrews/Daicoff Cardiovascular Program
Surgical Director of Heart Transplantation
Johns Hopkins All Children’s Heart Institute
Johns Hopkins All Children’s Hospital and Florida Hospital for Children
The U.S. News Rankings:
Future Role of the Reputation Survey
U.S. News & World Report
Healthcare of Tomorrow
November 3, 2017
•  Chair, STS National Database Workforce
•  Chair, CHSS Committee on Quality Improvement
and Outcomes
•  Working Group Leader, Heart/Heart Surgery
Working Group for U.S. News America's Best
Children's Hospitals rankings
•  Editor-in-Chief, Cardiology in the Young
•  Co-Chair, World Congress of Pediatric Cardiology
and Cardiac Surgery 2021
Disclosure
Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric and Congenital Cardiac Care - Volume 1: Outcomes
Analysis. Springer-Verlag London. Pages 1 – 515. ISBN: 978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online).
Published in 2014.
Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric and Congenital Cardiac Care - Volume 2: Quality
Improvement and Patient Safety. Springer-Verlag London. 2015, Pages 1 – 456. ISBN: 978-1-4471-6565-1 (Print).
978-1-4471-6566-8 (Online). Published in 2014.
•  2008: Introduction of pediatric specialties. Heart &
Heart Surgery was 50% reputation, 40% structure,
10% outcomes; weights varied slightly in other
specialties.
Reputation Score:
Pediatric Cardiology & Heart Surgery
•  2008: Introduction of pediatric specialties. Heart &
Heart Surgery was 50% reputation, 40% structure,
10% outcomes; weights varied slightly in other
specialties.
•  2010: Decreased weight of reputation from 50%
to 35% reputation in all specialties. 40% structure,
25% outcomes.
Reputation Score:
Pediatric Cardiology & Heart Surgery
•  2008: Introduction of pediatric specialties. Heart & Heart
Surgery was 50% reputation, 40% structure, 10%
outcomes; weights varied slightly in other specialties.
•  2010: Decreased weight of reputation from 50% to
35% reputation in all specialties. 40% structure, 25%
outcomes.
•  2011: Decreased weight of reputation from 35% to 25%
reputation in all specialties. 40% structure, 35%
outcomes.
Reputation Score:
Pediatric Cardiology & Heart Surgery
•  2008: Introduction of pediatric specialties. Heart & Heart
Surgery was 50% reputation, 40% structure, 10%
outcomes; weights varied slightly in other specialties.
•  2010: Decreased weight of reputation from 50% to 35%
reputation in all specialties. 40% structure, 25% outcomes.
•  2011: Decreased weight of reputation from 35% to 25%
reputation in all specialties. 40% structure, 35% outcomes.
•  2014: Decreased weight of reputation from 25% to 16.7% in
all pediatric specialties
Reputation Score:
Pediatric Cardiology & Heart Surgery
•  2008: Introduction of pediatric specialties. Heart & Heart Surgery
was 50% reputation, 40% structure, 10% outcomes; weights
varied slightly in other specialties.
•  2010: Decreased weight of reputation from 50% to 35%
reputation in all specialties. 40% structure, 25% outcomes.
•  2011: Decreased weight of reputation from 35% to 25% reputation
in all specialties. 40% structure, 35% outcomes.
•  2014: Decreased weight of reputation from 25% to 16.7% in all
pediatric specialties
•  2016: Decreased weight of reputation from 16.7% to 15% in all
pediatric specialties, and gave pediatric hospitals credit for being
publicly transparent about their pediatric STS outcomes
Reputation Score:
Pediatric Cardiology & Heart Surgery
•  2008: Introduction of pediatric specialties. Heart & Heart Surgery was 50%
reputation, 40% structure, 10% outcomes; weights varied slightly in other
specialties.
•  2010: Decreased weight of reputation from 50% to 35% reputation in all
specialties. 40% structure, 25% outcomes.
•  2011: Decreased weight of reputation from 35% to 25% reputation in all
specialties. 40% structure, 35% outcomes.
•  2014: Decreased weight of reputation from 25% to 16.7% in all pediatric
specialties
•  2016: Decreased weight of reputation from 16.7% to 15% in all pediatric
specialties, and gave pediatric hospitals credit for being publicly transparent
about their pediatric STS outcomes
•  2017: Decreased weight of reputation from 15% to 8.5% in pediatric Cardiology
& Heart Surgery. Remained at 15% in all other pediatric specialties.
Reputation Score:
Pediatric Cardiology & Heart Surgery
10
Modeling Change to US News Rankings after Removal of
Reputation scores (Specialty: Cardiology & Heart Surgery)
•  Largest	Posi,ve	change	=	+7	
•  Largest	Nega,ve	change	=	-19	
•  Number	of	No	change			=				9	(17%)	
•  Number	of	pos.	change	=		25	(49%)	
•  Number	of	neg.	change	=		17	(33%)	
•  Average	Ranking	change	+/-	3.3	
9		hospitals	with	no	
change		
25	hospitals	with	
pos.	change		
17	hospitals	with	
neg.	change		
Largest	pos.	
change	(+7)	
Largest	neg..	
change	(-19)
11
Modeling Change to US News Rankings after Removal of
Reputation scores (Specialty: Cardiology & Heart Surgery)
•  Largest	Posi,ve	change	=	+7	
•  Largest	Nega,ve	change	=	-19	
•  Number	of	No	change			=				9	(17%)	
•  Number	of	pos.	change	=		25	(49%)	
•  Number	of	neg.	change	=		17	(33%)	
•  Average	Ranking	change	+/-	3.3	
9		hospitals	with	no	
change		
25	hospitals	with	
pos.	change		
17	hospitals	with	
neg.	change		
Largest	pos.	
change	(+7)	
Largest	neg..	
change	(-19)
12
Modeling Change to US News Rankings after Removal of
Reputation scores (Specialty: Cardiology & Heart Surgery)
•  Largest	Posi,ve	change	=	+7	
•  Largest	Nega,ve	change	=	-19	
•  Number	of	No	change			=				9	(17%)	
•  Number	of	pos.	change	=		25	(49%)	
•  Number	of	neg.	change	=		17	(33%)	
•  Average	Ranking	change	+/-	3.3	
9		hospitals	with	no	
change		
25	hospitals	with	
pos.	change		
17	hospitals	with	
neg.	change		
Largest	pos.	
change	(+7)	
Largest	neg..	
change	(-19)
13
Modeling Change to US News Rankings after Removal of
Reputation scores (Specialty: Cardiology & Heart Surgery)
•  Largest	Posi,ve	change	=	+7	
•  Largest	Nega,ve	change	=	-19	
•  Number	of	No	change			=				9	(17%)	
•  Number	of	pos.	change	=		25	(49%)	
•  Number	of	neg.	change	=		17	(33%)	
•  Average	Ranking	change	+/-	3.3	
9		hospitals	with	no	
change		
25	hospitals	with	
pos.	change		
17	hospitals	with	
neg.	change		
Largest	pos.	
change	(+7)	
Largest	neg..	
change	(-19)
•  We obtained the Total Raw Scores for the Cardiology and Heart Surgery Specialty
from the HDI Pediatrics analytic platform (USNWR 2017 rankings)
•  We obtained the Reputation values from HDI Pediatrics analytic platform
–  Also found in “2017-18 Best Children’s Hospitals Rankings by Specialty” document
–  Field = Reputation with Physicians in Specialty
•  We calculated the Reputation Score contribution by using US News formula*
•  We calculated the New Total Raw Scores by subtracting Reputation Score
•  We found Hospital rankings based on new Total Raw Scores without the Reputation
factor
•  We selected the top 50 Hospitals from original ranking and compared their new
ranking without reputation to their original ranking
•  We charted the differences between original and new rankings.
•  (see chart on next slide)
Methodology for obtaining USNWR 2017 ranking without
reputation score using US News Hospital Data Insights (HDI)
Pediatrics analytic platform:
	
*			Reputa,on	Contribu,on	to	Total	Raw	Score	=	
(((Log(R+10)	-1)*10		)/	P	)*	W	
R	=	ques,on	result		P	=	possible	points		W	=	weight
Methodology: Calculation example
Total	Score	
Original	Ranking	 33/50	 P	=		10.41	 Possible	points	
Total	Raw	Score	 74.3	 W	=	8.48	 Weight	
Reputa,on	Value	 2.1	 R	=	2.1	 Ques,on	Value	
Formula	to	find	
Reputa,on	Score	
Contribu,on	to	Total	
Raw	Score	
(((Log(R+10)	
-1)*10	)/	P	)*	W		
	
(((Log(2.1+10)	
-1)*10	)/	10.41	)*	
8.48			
	=	.675	
Possible	Points	=	
P	=	10.41	
Weight	=	W	=	
8.48	
Result	Value	=	R	=	
2.1	
	
Reputa,on	Score	 .675	
New	Total	Raw	Score	 73.35	 74.0	-	.675		=		
73.35	
	
New	Ranking	based	on	
New	score	
31/50
•  how good or bad something is
•  a characteristic or feature that someone or
something has : something that can be noticed
as a part of a person or thing
•  a high level of value or excellence.
Definition of Quality
[http://www.merriam-webster.com/dictionary/quality].
Accessed November 10, 2015
Donabedian’s Triad
Donabedian	A.	Evalua.ng	the	quality	of	medical	care.		
Milbank	Mem	Fund	Q.	1966;44(Suppl):166–206.
Michael Porter
value	defined	as	the	health	outcomes	achieved	per	dollar	spent	
Michael	E.	Porter,	Ph.D.		Perspec,ve.		What	Is	Value	in	Health	Care?		
N	Engl	J	Med	2010;	363:2477-2481
Congenital Heart Disease
Meaningful
Multi-institutional Outcomes Analysis
Accomplishments
1)  Common Language = Nomenclature
2)  Mechanism of Data Collection (Database - Registry)
3)  Mechanism of Evaluating Case Complexity
4)  Mechanism to Verify Data Validity and Accuracy
5)  Collaboration Between Subspecialties
6)  Longitudinal Follow-Up and Linked Databases
7)  Quality Improvement
Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric
and Congenital Cardiac Care - Volume 1: Outcomes Analysis.
Springer-Verlag London. Pages 1 – 515. ISBN:
978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online).
Congenital Heart Disease
Meaningful
Multi-institutional Outcomes Analysis
Accomplishments
1)  Common Language = Nomenclature
2)  Mechanism of Data Collection (Database - Registry)
3)  Mechanism of Evaluating Case Complexity
4)  Mechanism to Verify Data Validity and Accuracy
5)  Collaboration Between Subspecialties
6)  Longitudinal Follow-Up and Linked Databases
7)  Quality Improvement
Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric
and Congenital Cardiac Care - Volume 1: Outcomes Analysis.
Springer-Verlag London. Pages 1 – 515. ISBN:
978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online).
The validity of coding of lesions seen in
the congenitally malformed heart via the
International Classification of Diseases
(ICD) is poor
1.  Cronk CE, Malloy ME, Pelech AN, et al. Completeness of state administrative databases for
surveillance of congenital heart disease. Birth Defects Res A Clin Mol Teratol 2003;67:597-603.
2.  Frohnert BK, Lussky RC, Alms MA, Mendelsohn NJ, Symonik DM, Falken MC. Validity of hospital
discharge data for identifying infants with cardiac defects. J Perinatol 2005;25:737-42.
3.  Strickland MJ, Riehle-Colarusso TJ, Jacobs JP, Reller MD, Mahle WT, Botto LD, Tolbert PE, Jacobs
ML, Lacour-Gayet FG, Tchervenkov CI, Mavroudis C, Correa A. The importance of nomenclature
for congenital cardiac disease: implications for research and evaluation. In: 2008 Cardiology
in the Young Supplement: Databases and The Assessment of Complications associated with The
Treatment of Patients with Congenital Cardiac Disease, Prepared by: The Multi-Societal Database
Committee for Pediatric and Congenital Heart Disease, Jeffrey P. Jacobs, MD (editor). Cardiology in
the Young, Volume 18, Issue S2 (Suppl. 2), pp 92–100, December 9, 2008.
4.  Pasquali SK, Peterson ED, Jacobs JP, He X, Li JS, Jacobs ML, Gaynor JW, Hirsch JC, Shah SS,
Mayer JE. Differential case ascertainment in clinical registry versus administrative data and
impact on outcomes assessment for pediatric cardiac operations. Ann Thorac Surg. 2013 Jan;
95(1):197-203. doi: 10.1016/j.athoracsur.2012.08.074. Epub 2012 Nov 7. PMID: 23141907.
International Paediatric and Congenital Cardiac Code
(IPCCC)
and
Eleventh Iteration of the International Classification of
Diseases
(ICD-11)
www.ipccc.net
Congenital Heart Disease
Meaningful
Multi-institutional Outcomes Analysis
Accomplishments
1)  Common Language = Nomenclature
2)  Mechanism of Data Collection (Database - Registry)
3)  Mechanism of Evaluating Case Complexity
4)  Mechanism to Verify Data Validity and Accuracy
5)  Collaboration Between Subspecialties
6)  Longitudinal Follow-Up and Linked Databases
7)  Quality Improvement
Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric
and Congenital Cardiac Care - Volume 1: Outcomes Analysis.
Springer-Verlag London. Pages 1 – 515. ISBN:
978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online).
The Report of the 2015 STS
Congenital Heart Surgery
Practice Survey
  undertaken by the Society of Thoracic
Surgeons Workforce on Congenital Heart
Surgery
  125 centers in the United States of
America perform pediatric and congenital
heart surgery
  8 centers in Canada perform pediatric
and congenital heart surgery
Morales DL, Khan MS, Turek JW, Biniwale R, Tchervenkov CI, Rush M, Jacobs JP, Tweddell
JS, Jacobs ML. Report of the 2015 Society of Thoracic Surgeons Congenital Heart
Surgery Practice Survey. Ann Thorac Surg. 2017 Feb;103(2):622-628. doi: 10.1016/
j.athoracsur.2016.05.108. Epub 2016 Aug 20. PMID: 27553498.
Jacobs JP, Jacobs ML, Mavroudis C, Tchervenkov CI, Pasquali SK. Executive Summary: The Society of Thoracic
Surgeons Congenital Heart Surgery Database – Twenty-sixth Harvest – (January 1, 2013 – December 31, 2016).
The Society of Thoracic Surgeons (STS) and Duke Clinical Research Institute (DCRI), Duke University Medical
Center, Durham, North Carolina, United States, Spring 2017 Harvest.
2003	 2004	 2005	 2006	 2007	 2008	 2009	 2010	 2011	 2012	 2013	 2014	 2015	 2016	
Par,cipa,ng	Centers	 18	 21	 34	 47	 58	 68	 79	 93	 101	 105	 111	 113	 117	 116	
18	
21	
34	
47	
58	
68	
79	
93	
101	
105	
111	
113	
117	 116	
0	
20	
40	
60	
80	
100	
120	
140	
Growth	in	the	STS	Congenital	Heart	Surgery	Database	
Par.cipa.ng	Centers	Per	Harvest
Jacobs JP, Jacobs ML, Mavroudis C, Tchervenkov CI, Pasquali SK. Executive Summary: The Society of Thoracic
Surgeons Congenital Heart Surgery Database – Twenty-sixth Harvest – (January 1, 2013 – December 31, 2016).
The Society of Thoracic Surgeons (STS) and Duke Clinical Research Institute (DCRI), Duke University Medical
Center, Durham, North Carolina, United States, Spring 2017 Harvest.
2003	 2004	 2005	 2006	 2007	 2008	 2009	 2010	 2011	 2012	 2013	 2014	 2015	 2016	
Opera,ons	 16,461	 28,351	 37,093	 45,635	 61,014	 72,002	 91,639	 103,664	 114,041	 130,823	 136,617	 143,842	 153,558	 157,357	
16,461	
28,351	
37,093	
45,635	
61,014	
72,002	
91,639	
103,664	
114,041	
130,823	
136,617	
143,842	
153,558	
157,357	
0	
20,000	
40,000	
60,000	
80,000	
100,000	
120,000	
140,000	
160,000	
180,000	
Growth	in	the	STS	Congenital	Heart	Surgery	Database	
Opera.ons	per	averaged	4	year	data	collec.on	cycle
Jacobs JP, Jacobs ML, Mavroudis C, Tchervenkov CI, Pasquali SK. Executive Summary: The Society of Thoracic
Surgeons Congenital Heart Surgery Database – Twenty-sixth Harvest – (January 1, 2013 – December 31, 2016).
The Society of Thoracic Surgeons (STS) and Duke Clinical Research Institute (DCRI), Duke University Medical
Center, Durham, North Carolina, United States, Spring 2017 Harvest.
2001	 2002	 2003	 2004	 2005	 2006	 2007	 2008	 2009	 2010	 2011	 2012	 2013	 2014	 2015	 2016	
Cumula,ve	Opera,ons	 9,747	 16,537	 26,404	 39,988	 58,181	 79,399	 98,406	 119,266	 148,110	 179,697	 213,416	 257,932	 292,828	 331,672	 394,980	 435,373	
9,747	 16,537	
26,404	
39,988	
58,181	
79,399	
98,406	
119,266	
148,110	
179,697	
213,416	
257,932	
292,828	
331,672	
394,980	
435,373	
0	
50,000	
100,000	
150,000	
200,000	
250,000	
300,000	
350,000	
400,000	
450,000	
500,000	
Growth	in	the	STS	Congenital	Heart	Surgery	Database	
Cumula.ve	opera.ons	over	.me
STS Database
Penetrance in USA
  The STS Congenital Heart Surgery Database (STS-CHSD) is the largest
clinical database in the world for congenital and pediatric cardiac
surgery.
  The Report of the 2010 STS Congenital Heart Surgery Practice and
Manpower Survey, undertaken by the STS Workforce on Congenital Heart
Surgery, documented that 125 hospitals in the United States of America
and 8 hospitals in Canada perform pediatric and congenital heart
surgery.
  The STS-CHSD contains data from 120 of the 125 hospitals (96%
penetrance by hospital) in the United States of America and 3 of the 8
centers in Canada.
STS Database
Penetrance in USA
  The STS Congenital Heart Surgery Database (STS-CHSD) is the largest
clinical database in the world for congenital and pediatric cardiac
surgery.
  The Report of the 2010 STS Congenital Heart Surgery Practice and
Manpower Survey, undertaken by the STS Workforce on Congenital Heart
Surgery, documented that 125 hospitals in the United States of America
and 8 hospitals in Canada perform pediatric and congenital heart
surgery.
  The STS-CHSD contains data from 120 of the 125 hospitals (96%
penetrance by hospital) in the United States of America and 3 of the 8
centers in Canada.
REPRESENTATIVE
Congenital Heart Disease
Meaningful
Multi-institutional Outcomes Analysis
Accomplishments
1)  Common Language = Nomenclature
2)  Mechanism of Data Collection (Database - Registry)
3)  Mechanism of Evaluating Case Complexity
4)  Mechanism to Verify Data Validity and Accuracy
5)  Collaboration Between Subspecialties
6)  Longitudinal Follow-Up and Linked Databases
7)  Quality Improvement
Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric
and Congenital Cardiac Care - Volume 1: Outcomes Analysis.
Springer-Verlag London. Pages 1 – 515. ISBN:
978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online).
Adjustment for
Case Mix
“Differences in medical outcomes may result from
disease severity, treatment effectiveness, or
chance.
Because most outcome studies are observational….
risk adjustment is necessary to account for case mix”
Shahian DM, Blackstone EH, Edwards FH, Grover FL,
Grunkemeier GL, Naftel DC, Nashef SA, Nugent WC, Peterson
ED. STS workforce on evidence-based surgery. Cardiac
surgery risk models: a position article. Ann Thorac Surg.
2004;78(5):1868–77
0
5
10
15
20
% Mortality
% Mortality 0.78 2.1 3.4 8.5 19.9
1 2 3 4 5STAT Category
Combined ECHSA/EACTS and STS Congenital
Heart Surgery Databases:
111,494 index cardiac
operations
Jacobs JP, Jacobs ML, Maruszewski B, Lacour-Gayet FG, Tchervenkov CI, Tobota Z, Stellin G, Kurosawa H,
Murakami A, Gaynor JW, Pasquali SK, Clarke DR, Austin EH 3rd, Mavroudis C. Initial application in the EACTS
and STS Congenital Heart Surgery Databases of an empirically derived methodology of complexity
adjustment to evaluate surgical case mix and results. Eur J Cardiothorac Surg. 2012 Nov;42(5):775-80. doi:
10.1093/ejcts/ezs026. Epub 2012 Jun 14. PMID: 22700597.
STS Congenital Heart Surgery
Database Mortality Risk Model
Variable
Age a
Primary procedure b
Weight (neonates and infants)
Prior cardiothoracic operation
Any non-cardiac congenital anatomic abnormality (except ‘Other noncardiac congenital abnormality’
with code value = 990)
Any chromosomal abnormality or syndrome (except ‘Other chromosomal abnormality’ with code
value = 310 and except ‘Other syndromic abnormality’ with code value = 510)
Prematurity (neonates and infants)
Preoperative Factors
• Preoperative/Preprocedural mechanical circulatory support (IABP, VAD, ECMO, or CPS) c
• Shock, Persistent at time of surgery
• Mechanical ventilation to treat cardiorespiratory failure
• Renal failure requiring dialysis and/or Renal dysfunction
• Preoperative neurological deficit
• Any other preoperative factor (except ‘Other preoperative factors’ with code value = 777) d
a Modeled as a piecewise linear function with separate intercepts and slopes for each STS-defined age group
(neonate, infant, child, adult).
b The model adjusts for each combination of primary procedure and age group. Coefficients obtained via
shrinkage estimation with The Society of Thoracic Surgeons–European Association for Cardio-Thoracic
Surgery (STS-EACTS [STAT]) Mortality Category as an auxiliary variable.
c CPS	=	cardiopulmonary	support;	ECMO	=extracorporeal	membrane	oxygenation;	IABP	=	intraaortic	balloon	
pump;	VAD	=	ventricular	assist	device
d Any other preoperative factor is defined as any of the other specified preoperative factors contained in the list
of preoperative factors in the data collection form of the STS Congenital Heart Surgery Database, exclusive of
777 = ‘Other preoperative factors’.
• All index cardiac operations in the STS-CHSD
(January 1, 2010–December 31, 2013) were
eligible for inclusion.
• Isolated PDA closures in patients <2.5kg were
excluded, as were centers with >10%
missing data and patients with missing data
for key variables.
STS Congenital Heart Surgery
Database Mortality Risk Model
52,224 operations
from 86 centers were
included
STS Congenital Heart Surgery
Database Mortality Risk Model
Model	
		
Covariates	
Development		
Sample	C-Stat	
Valida.on		
Sample	C-Stat	
1	 STAT	Levels	
C	=	0.772	 C	=	0.787	
2	 STAT	Levels	+		
age	and	weight	 C	=	0.818	 C	=	0.817	
3	 STAT	Levels	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.862	 C	=	0.852	
4	 Primary	procedure	+		
age	and	weight	 C	=	0.846	 C	=	0.831	
(Final	Model)	 Primary	procedure	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.875	 C	=	0.858	
STS Congenital Heart Surgery
Database Mortality Risk Model
Model	
		
Covariates	
Development		
Sample	C-Stat	
Valida.on		
Sample	C-Stat	
1	 STAT	Levels	
C	=	0.772	 C	=	0.787	
2	 STAT	Levels	+		
age	and	weight	 C	=	0.818	 C	=	0.817	
3	 STAT	Levels	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.862	 C	=	0.852	
4	 Primary	procedure	+		
age	and	weight	 C	=	0.846	 C	=	0.831	
(Final	Model)	 Primary	procedure	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.875	 C	=	0.858	
STS Congenital Heart Surgery
Database Mortality Risk Model
Model	
		
Covariates	
Development		
Sample	C-Stat	
Valida.on		
Sample	C-Stat	
1	 STAT	Levels	
C	=	0.772	 C	=	0.787	
2	 STAT	Levels	+		
age	and	weight	 C	=	0.818	 C	=	0.817	
3	 STAT	Levels	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.862	 C	=	0.852	
4	 Primary	procedure	+		
age	and	weight	 C	=	0.846	 C	=	0.831	
(Final	Model)	 Primary	procedure	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.875	 C	=	0.858	
STS Congenital Heart Surgery
Database Mortality Risk Model
Model	
		
Covariates	
Development		
Sample	C-Stat	
Valida.on		
Sample	C-Stat	
1	 STAT	Levels	
C	=	0.772	 C	=	0.787	
2	 STAT	Levels	+		
age	and	weight	 C	=	0.818	 C	=	0.817	
3	 STAT	Levels	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.862	 C	=	0.852	
4	 Primary	procedure	+		
age	and	weight	 C	=	0.846	 C	=	0.831	
(Final	Model)	 Primary	procedure	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.875	 C	=	0.858	
STS Congenital Heart Surgery
Database Mortality Risk Model
Model	
		
Covariates	
Development		
Sample	C-Stat	
Valida.on		
Sample	C-Stat	
1	 STAT	Levels	
C	=	0.772	 C	=	0.787	
2	 STAT	Levels	+		
age	and	weight	 C	=	0.818	 C	=	0.817	
3	 STAT	Levels	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.862	 C	=	0.852	
4	 Primary	procedure	+		
age	and	weight	 C	=	0.846	 C	=	0.831	
(Final	Model)	 Primary	procedure	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.875	 C	=	0.858	
STS Congenital Heart Surgery
Database Mortality Risk Model
Model	
		
Covariates	
Development		
Sample	C-Stat	
Valida.on		
Sample	C-Stat	
1	 STAT	Levels	
C	=	0.772	 C	=	0.787	
2	 STAT	Levels	+		
age	and	weight	 C	=	0.818	 C	=	0.817	
3	 STAT	Levels	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.862	 C	=	0.852	
4	 Primary	procedure	+		
age	and	weight	 C	=	0.846	 C	=	0.831	
(Final	Model)	 Primary	procedure	+		
age	and	weight	+	
pa,ent	factors	
C	=	0.875	 C	=	0.858	
STS Congenital Heart Surgery
Database Mortality Risk Model
42	
Fig 1. Distribution of hospital-specific observed-to-expected (O/E)
ratios for operative mortality with 95% confidence intervals (gray
lines).
STS Congenital Heart Surgery
Database Mortality Risk Model
43	
Fig 1. Distribution of hospital-specific observed-to-expected (O/E)
ratios for operative mortality with 95% confidence intervals (gray
lines).
STS Congenital Heart Surgery
Database Mortality Risk Model
44	
Fig 1. Distribution of hospital-specific observed-to-expected (O/E)
ratios for operative mortality with 95% confidence intervals (gray
lines).
STS Congenital Heart Surgery
Database Mortality Risk Model
45	
Fig 1. Distribution of hospital-specific observed-to-expected (O/E)
ratios for operative mortality with 95% confidence intervals (gray
lines).
STS Congenital Heart Surgery
Database Mortality Risk Model
46	
Fig 1. Distribution of hospital-specific observed-to-expected (O/E)
ratios for operative mortality with 95% confidence intervals (gray
lines).
STS Congenital Heart Surgery
Database Mortality Risk Model
Congenital Heart Disease
Meaningful
Multi-institutional Outcomes Analysis
Accomplishments
1)  Common Language = Nomenclature
2)  Mechanism of Data Collection (Database - Registry)
3)  Mechanism of Evaluating Case Complexity
4)  Mechanism to Verify Data Validity and Accuracy
5)  Collaboration Between Subspecialties
6)  Longitudinal Follow-Up and Linked Databases
7)  Quality Improvement
Barach	P,	Jacobs	JP,	Lipshultz	SE,	Laussen	P.	(Eds.).	Pediatric	and	
Congenital	Cardiac	Care	-	Volume	1:	Outcomes	Analysis.		
Springer-Verlag	London.	Pages	1	–	515.		ISBN:	978-1-4471-6586-6	
(Print).		978-1-4471-6587-3	(Online).		Published	in	2014.
STS CHSD Data
Verification
10% of sites audited each year
Analysis of general variables
–  data completeness rate of 99.94% and
–  overall data agreement rate of 98.05%
Analysis of mortality variables
–  data completeness rate of 100% and
–  overall data agreement rate of 99.09%
Congenital Heart Disease
Meaningful
Multi-institutional Outcomes Analysis
Accomplishments
1)  Common Language = Nomenclature
2)  Mechanism of Data Collection (Database - Registry)
3)  Mechanism of Evaluating Case Complexity
4)  Mechanism to Verify Data Validity and Accuracy
5)  Collaboration Between Subspecialties
6)  Longitudinal Follow-Up and Linked Databases
7)  Quality Improvement
Barach	P,	Jacobs	JP,	Lipshultz	SE,	Laussen	P.	(Eds.).	Pediatric	and	
Congenital	Cardiac	Care	-	Volume	1:	Outcomes	Analysis.		
Springer-Verlag	London.	Pages	1	–	515.		ISBN:	978-1-4471-6586-6	
(Print).		978-1-4471-6587-3	(Online).		Published	in	2014.
Jacobs JP. (Editor). 2008 Cardiology in the Young
Supplement: Databases and The Assessment of
Complications associated with The Treatment of Patients
with Congenital Cardiac Disease, Prepared by: The Multi-
Societal Database Committee for Pediatric and Congenital
Heart Disease, Cardiology in the Young, Volume 18, Supplement
S2, pages 1 –530, December 9, 2008.
Collaboration Between Subspecialties
Accomplishments
1)  STS Congenital Heart Surgery Database
2)  IMPACT Database of the American College of
Cardiology (Interventional Cardiology)
3)  MAP-IT: Multicenter Pediatric and Adult Congenital EP
Common Language = Nomenclature
4)  Pediatric Cardiac Critical Care Consortium (PC4)
5)  Congenital Cardiac Anesthesia Society Database
(CCAS)
“Science tells us what we can do;
Guidelines what we should do; &
Registries what we are actually doing.”
Outcomes	Analysis	
Pa.ent	Safety	
Quality	
Improvement

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The U.S. News Rankings: Future Role of the Reputation Survey (Jeffery Jacobs)

  • 1. Jeffrey P. Jacobs, M.D., FACS, FACC, FCCP Professor of Surgery and Pediatrics, Johns Hopkins University Co-Director, Johns Hopkins All Children’s Heart Institute Chief, Division of Cardiovascular Surgery Director, Andrews/Daicoff Cardiovascular Program Surgical Director of Heart Transplantation Johns Hopkins All Children’s Heart Institute Johns Hopkins All Children’s Hospital and Florida Hospital for Children The U.S. News Rankings: Future Role of the Reputation Survey U.S. News & World Report Healthcare of Tomorrow November 3, 2017
  • 2. •  Chair, STS National Database Workforce •  Chair, CHSS Committee on Quality Improvement and Outcomes •  Working Group Leader, Heart/Heart Surgery Working Group for U.S. News America's Best Children's Hospitals rankings •  Editor-in-Chief, Cardiology in the Young •  Co-Chair, World Congress of Pediatric Cardiology and Cardiac Surgery 2021 Disclosure
  • 3. Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric and Congenital Cardiac Care - Volume 1: Outcomes Analysis. Springer-Verlag London. Pages 1 – 515. ISBN: 978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online). Published in 2014. Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric and Congenital Cardiac Care - Volume 2: Quality Improvement and Patient Safety. Springer-Verlag London. 2015, Pages 1 – 456. ISBN: 978-1-4471-6565-1 (Print). 978-1-4471-6566-8 (Online). Published in 2014.
  • 4. •  2008: Introduction of pediatric specialties. Heart & Heart Surgery was 50% reputation, 40% structure, 10% outcomes; weights varied slightly in other specialties. Reputation Score: Pediatric Cardiology & Heart Surgery
  • 5. •  2008: Introduction of pediatric specialties. Heart & Heart Surgery was 50% reputation, 40% structure, 10% outcomes; weights varied slightly in other specialties. •  2010: Decreased weight of reputation from 50% to 35% reputation in all specialties. 40% structure, 25% outcomes. Reputation Score: Pediatric Cardiology & Heart Surgery
  • 6. •  2008: Introduction of pediatric specialties. Heart & Heart Surgery was 50% reputation, 40% structure, 10% outcomes; weights varied slightly in other specialties. •  2010: Decreased weight of reputation from 50% to 35% reputation in all specialties. 40% structure, 25% outcomes. •  2011: Decreased weight of reputation from 35% to 25% reputation in all specialties. 40% structure, 35% outcomes. Reputation Score: Pediatric Cardiology & Heart Surgery
  • 7. •  2008: Introduction of pediatric specialties. Heart & Heart Surgery was 50% reputation, 40% structure, 10% outcomes; weights varied slightly in other specialties. •  2010: Decreased weight of reputation from 50% to 35% reputation in all specialties. 40% structure, 25% outcomes. •  2011: Decreased weight of reputation from 35% to 25% reputation in all specialties. 40% structure, 35% outcomes. •  2014: Decreased weight of reputation from 25% to 16.7% in all pediatric specialties Reputation Score: Pediatric Cardiology & Heart Surgery
  • 8. •  2008: Introduction of pediatric specialties. Heart & Heart Surgery was 50% reputation, 40% structure, 10% outcomes; weights varied slightly in other specialties. •  2010: Decreased weight of reputation from 50% to 35% reputation in all specialties. 40% structure, 25% outcomes. •  2011: Decreased weight of reputation from 35% to 25% reputation in all specialties. 40% structure, 35% outcomes. •  2014: Decreased weight of reputation from 25% to 16.7% in all pediatric specialties •  2016: Decreased weight of reputation from 16.7% to 15% in all pediatric specialties, and gave pediatric hospitals credit for being publicly transparent about their pediatric STS outcomes Reputation Score: Pediatric Cardiology & Heart Surgery
  • 9. •  2008: Introduction of pediatric specialties. Heart & Heart Surgery was 50% reputation, 40% structure, 10% outcomes; weights varied slightly in other specialties. •  2010: Decreased weight of reputation from 50% to 35% reputation in all specialties. 40% structure, 25% outcomes. •  2011: Decreased weight of reputation from 35% to 25% reputation in all specialties. 40% structure, 35% outcomes. •  2014: Decreased weight of reputation from 25% to 16.7% in all pediatric specialties •  2016: Decreased weight of reputation from 16.7% to 15% in all pediatric specialties, and gave pediatric hospitals credit for being publicly transparent about their pediatric STS outcomes •  2017: Decreased weight of reputation from 15% to 8.5% in pediatric Cardiology & Heart Surgery. Remained at 15% in all other pediatric specialties. Reputation Score: Pediatric Cardiology & Heart Surgery
  • 10. 10 Modeling Change to US News Rankings after Removal of Reputation scores (Specialty: Cardiology & Heart Surgery) •  Largest Posi,ve change = +7 •  Largest Nega,ve change = -19 •  Number of No change = 9 (17%) •  Number of pos. change = 25 (49%) •  Number of neg. change = 17 (33%) •  Average Ranking change +/- 3.3 9 hospitals with no change 25 hospitals with pos. change 17 hospitals with neg. change Largest pos. change (+7) Largest neg.. change (-19)
  • 11. 11 Modeling Change to US News Rankings after Removal of Reputation scores (Specialty: Cardiology & Heart Surgery) •  Largest Posi,ve change = +7 •  Largest Nega,ve change = -19 •  Number of No change = 9 (17%) •  Number of pos. change = 25 (49%) •  Number of neg. change = 17 (33%) •  Average Ranking change +/- 3.3 9 hospitals with no change 25 hospitals with pos. change 17 hospitals with neg. change Largest pos. change (+7) Largest neg.. change (-19)
  • 12. 12 Modeling Change to US News Rankings after Removal of Reputation scores (Specialty: Cardiology & Heart Surgery) •  Largest Posi,ve change = +7 •  Largest Nega,ve change = -19 •  Number of No change = 9 (17%) •  Number of pos. change = 25 (49%) •  Number of neg. change = 17 (33%) •  Average Ranking change +/- 3.3 9 hospitals with no change 25 hospitals with pos. change 17 hospitals with neg. change Largest pos. change (+7) Largest neg.. change (-19)
  • 13. 13 Modeling Change to US News Rankings after Removal of Reputation scores (Specialty: Cardiology & Heart Surgery) •  Largest Posi,ve change = +7 •  Largest Nega,ve change = -19 •  Number of No change = 9 (17%) •  Number of pos. change = 25 (49%) •  Number of neg. change = 17 (33%) •  Average Ranking change +/- 3.3 9 hospitals with no change 25 hospitals with pos. change 17 hospitals with neg. change Largest pos. change (+7) Largest neg.. change (-19)
  • 14. •  We obtained the Total Raw Scores for the Cardiology and Heart Surgery Specialty from the HDI Pediatrics analytic platform (USNWR 2017 rankings) •  We obtained the Reputation values from HDI Pediatrics analytic platform –  Also found in “2017-18 Best Children’s Hospitals Rankings by Specialty” document –  Field = Reputation with Physicians in Specialty •  We calculated the Reputation Score contribution by using US News formula* •  We calculated the New Total Raw Scores by subtracting Reputation Score •  We found Hospital rankings based on new Total Raw Scores without the Reputation factor •  We selected the top 50 Hospitals from original ranking and compared their new ranking without reputation to their original ranking •  We charted the differences between original and new rankings. •  (see chart on next slide) Methodology for obtaining USNWR 2017 ranking without reputation score using US News Hospital Data Insights (HDI) Pediatrics analytic platform: * Reputa,on Contribu,on to Total Raw Score = (((Log(R+10) -1)*10 )/ P )* W R = ques,on result P = possible points W = weight
  • 15. Methodology: Calculation example Total Score Original Ranking 33/50 P = 10.41 Possible points Total Raw Score 74.3 W = 8.48 Weight Reputa,on Value 2.1 R = 2.1 Ques,on Value Formula to find Reputa,on Score Contribu,on to Total Raw Score (((Log(R+10) -1)*10 )/ P )* W (((Log(2.1+10) -1)*10 )/ 10.41 )* 8.48 = .675 Possible Points = P = 10.41 Weight = W = 8.48 Result Value = R = 2.1 Reputa,on Score .675 New Total Raw Score 73.35 74.0 - .675 = 73.35 New Ranking based on New score 31/50
  • 16. •  how good or bad something is •  a characteristic or feature that someone or something has : something that can be noticed as a part of a person or thing •  a high level of value or excellence. Definition of Quality [http://www.merriam-webster.com/dictionary/quality]. Accessed November 10, 2015
  • 19. Congenital Heart Disease Meaningful Multi-institutional Outcomes Analysis Accomplishments 1)  Common Language = Nomenclature 2)  Mechanism of Data Collection (Database - Registry) 3)  Mechanism of Evaluating Case Complexity 4)  Mechanism to Verify Data Validity and Accuracy 5)  Collaboration Between Subspecialties 6)  Longitudinal Follow-Up and Linked Databases 7)  Quality Improvement Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric and Congenital Cardiac Care - Volume 1: Outcomes Analysis. Springer-Verlag London. Pages 1 – 515. ISBN: 978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online).
  • 20. Congenital Heart Disease Meaningful Multi-institutional Outcomes Analysis Accomplishments 1)  Common Language = Nomenclature 2)  Mechanism of Data Collection (Database - Registry) 3)  Mechanism of Evaluating Case Complexity 4)  Mechanism to Verify Data Validity and Accuracy 5)  Collaboration Between Subspecialties 6)  Longitudinal Follow-Up and Linked Databases 7)  Quality Improvement Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric and Congenital Cardiac Care - Volume 1: Outcomes Analysis. Springer-Verlag London. Pages 1 – 515. ISBN: 978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online).
  • 21. The validity of coding of lesions seen in the congenitally malformed heart via the International Classification of Diseases (ICD) is poor 1.  Cronk CE, Malloy ME, Pelech AN, et al. Completeness of state administrative databases for surveillance of congenital heart disease. Birth Defects Res A Clin Mol Teratol 2003;67:597-603. 2.  Frohnert BK, Lussky RC, Alms MA, Mendelsohn NJ, Symonik DM, Falken MC. Validity of hospital discharge data for identifying infants with cardiac defects. J Perinatol 2005;25:737-42. 3.  Strickland MJ, Riehle-Colarusso TJ, Jacobs JP, Reller MD, Mahle WT, Botto LD, Tolbert PE, Jacobs ML, Lacour-Gayet FG, Tchervenkov CI, Mavroudis C, Correa A. The importance of nomenclature for congenital cardiac disease: implications for research and evaluation. In: 2008 Cardiology in the Young Supplement: Databases and The Assessment of Complications associated with The Treatment of Patients with Congenital Cardiac Disease, Prepared by: The Multi-Societal Database Committee for Pediatric and Congenital Heart Disease, Jeffrey P. Jacobs, MD (editor). Cardiology in the Young, Volume 18, Issue S2 (Suppl. 2), pp 92–100, December 9, 2008. 4.  Pasquali SK, Peterson ED, Jacobs JP, He X, Li JS, Jacobs ML, Gaynor JW, Hirsch JC, Shah SS, Mayer JE. Differential case ascertainment in clinical registry versus administrative data and impact on outcomes assessment for pediatric cardiac operations. Ann Thorac Surg. 2013 Jan; 95(1):197-203. doi: 10.1016/j.athoracsur.2012.08.074. Epub 2012 Nov 7. PMID: 23141907.
  • 22. International Paediatric and Congenital Cardiac Code (IPCCC) and Eleventh Iteration of the International Classification of Diseases (ICD-11) www.ipccc.net
  • 23. Congenital Heart Disease Meaningful Multi-institutional Outcomes Analysis Accomplishments 1)  Common Language = Nomenclature 2)  Mechanism of Data Collection (Database - Registry) 3)  Mechanism of Evaluating Case Complexity 4)  Mechanism to Verify Data Validity and Accuracy 5)  Collaboration Between Subspecialties 6)  Longitudinal Follow-Up and Linked Databases 7)  Quality Improvement Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric and Congenital Cardiac Care - Volume 1: Outcomes Analysis. Springer-Verlag London. Pages 1 – 515. ISBN: 978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online).
  • 24. The Report of the 2015 STS Congenital Heart Surgery Practice Survey   undertaken by the Society of Thoracic Surgeons Workforce on Congenital Heart Surgery   125 centers in the United States of America perform pediatric and congenital heart surgery   8 centers in Canada perform pediatric and congenital heart surgery Morales DL, Khan MS, Turek JW, Biniwale R, Tchervenkov CI, Rush M, Jacobs JP, Tweddell JS, Jacobs ML. Report of the 2015 Society of Thoracic Surgeons Congenital Heart Surgery Practice Survey. Ann Thorac Surg. 2017 Feb;103(2):622-628. doi: 10.1016/ j.athoracsur.2016.05.108. Epub 2016 Aug 20. PMID: 27553498.
  • 25. Jacobs JP, Jacobs ML, Mavroudis C, Tchervenkov CI, Pasquali SK. Executive Summary: The Society of Thoracic Surgeons Congenital Heart Surgery Database – Twenty-sixth Harvest – (January 1, 2013 – December 31, 2016). The Society of Thoracic Surgeons (STS) and Duke Clinical Research Institute (DCRI), Duke University Medical Center, Durham, North Carolina, United States, Spring 2017 Harvest. 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Par,cipa,ng Centers 18 21 34 47 58 68 79 93 101 105 111 113 117 116 18 21 34 47 58 68 79 93 101 105 111 113 117 116 0 20 40 60 80 100 120 140 Growth in the STS Congenital Heart Surgery Database Par.cipa.ng Centers Per Harvest
  • 26. Jacobs JP, Jacobs ML, Mavroudis C, Tchervenkov CI, Pasquali SK. Executive Summary: The Society of Thoracic Surgeons Congenital Heart Surgery Database – Twenty-sixth Harvest – (January 1, 2013 – December 31, 2016). The Society of Thoracic Surgeons (STS) and Duke Clinical Research Institute (DCRI), Duke University Medical Center, Durham, North Carolina, United States, Spring 2017 Harvest. 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Opera,ons 16,461 28,351 37,093 45,635 61,014 72,002 91,639 103,664 114,041 130,823 136,617 143,842 153,558 157,357 16,461 28,351 37,093 45,635 61,014 72,002 91,639 103,664 114,041 130,823 136,617 143,842 153,558 157,357 0 20,000 40,000 60,000 80,000 100,000 120,000 140,000 160,000 180,000 Growth in the STS Congenital Heart Surgery Database Opera.ons per averaged 4 year data collec.on cycle
  • 27. Jacobs JP, Jacobs ML, Mavroudis C, Tchervenkov CI, Pasquali SK. Executive Summary: The Society of Thoracic Surgeons Congenital Heart Surgery Database – Twenty-sixth Harvest – (January 1, 2013 – December 31, 2016). The Society of Thoracic Surgeons (STS) and Duke Clinical Research Institute (DCRI), Duke University Medical Center, Durham, North Carolina, United States, Spring 2017 Harvest. 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Cumula,ve Opera,ons 9,747 16,537 26,404 39,988 58,181 79,399 98,406 119,266 148,110 179,697 213,416 257,932 292,828 331,672 394,980 435,373 9,747 16,537 26,404 39,988 58,181 79,399 98,406 119,266 148,110 179,697 213,416 257,932 292,828 331,672 394,980 435,373 0 50,000 100,000 150,000 200,000 250,000 300,000 350,000 400,000 450,000 500,000 Growth in the STS Congenital Heart Surgery Database Cumula.ve opera.ons over .me
  • 28. STS Database Penetrance in USA   The STS Congenital Heart Surgery Database (STS-CHSD) is the largest clinical database in the world for congenital and pediatric cardiac surgery.   The Report of the 2010 STS Congenital Heart Surgery Practice and Manpower Survey, undertaken by the STS Workforce on Congenital Heart Surgery, documented that 125 hospitals in the United States of America and 8 hospitals in Canada perform pediatric and congenital heart surgery.   The STS-CHSD contains data from 120 of the 125 hospitals (96% penetrance by hospital) in the United States of America and 3 of the 8 centers in Canada.
  • 29. STS Database Penetrance in USA   The STS Congenital Heart Surgery Database (STS-CHSD) is the largest clinical database in the world for congenital and pediatric cardiac surgery.   The Report of the 2010 STS Congenital Heart Surgery Practice and Manpower Survey, undertaken by the STS Workforce on Congenital Heart Surgery, documented that 125 hospitals in the United States of America and 8 hospitals in Canada perform pediatric and congenital heart surgery.   The STS-CHSD contains data from 120 of the 125 hospitals (96% penetrance by hospital) in the United States of America and 3 of the 8 centers in Canada. REPRESENTATIVE
  • 30. Congenital Heart Disease Meaningful Multi-institutional Outcomes Analysis Accomplishments 1)  Common Language = Nomenclature 2)  Mechanism of Data Collection (Database - Registry) 3)  Mechanism of Evaluating Case Complexity 4)  Mechanism to Verify Data Validity and Accuracy 5)  Collaboration Between Subspecialties 6)  Longitudinal Follow-Up and Linked Databases 7)  Quality Improvement Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric and Congenital Cardiac Care - Volume 1: Outcomes Analysis. Springer-Verlag London. Pages 1 – 515. ISBN: 978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online).
  • 31. Adjustment for Case Mix “Differences in medical outcomes may result from disease severity, treatment effectiveness, or chance. Because most outcome studies are observational…. risk adjustment is necessary to account for case mix” Shahian DM, Blackstone EH, Edwards FH, Grover FL, Grunkemeier GL, Naftel DC, Nashef SA, Nugent WC, Peterson ED. STS workforce on evidence-based surgery. Cardiac surgery risk models: a position article. Ann Thorac Surg. 2004;78(5):1868–77
  • 32. 0 5 10 15 20 % Mortality % Mortality 0.78 2.1 3.4 8.5 19.9 1 2 3 4 5STAT Category Combined ECHSA/EACTS and STS Congenital Heart Surgery Databases: 111,494 index cardiac operations Jacobs JP, Jacobs ML, Maruszewski B, Lacour-Gayet FG, Tchervenkov CI, Tobota Z, Stellin G, Kurosawa H, Murakami A, Gaynor JW, Pasquali SK, Clarke DR, Austin EH 3rd, Mavroudis C. Initial application in the EACTS and STS Congenital Heart Surgery Databases of an empirically derived methodology of complexity adjustment to evaluate surgical case mix and results. Eur J Cardiothorac Surg. 2012 Nov;42(5):775-80. doi: 10.1093/ejcts/ezs026. Epub 2012 Jun 14. PMID: 22700597.
  • 33. STS Congenital Heart Surgery Database Mortality Risk Model Variable Age a Primary procedure b Weight (neonates and infants) Prior cardiothoracic operation Any non-cardiac congenital anatomic abnormality (except ‘Other noncardiac congenital abnormality’ with code value = 990) Any chromosomal abnormality or syndrome (except ‘Other chromosomal abnormality’ with code value = 310 and except ‘Other syndromic abnormality’ with code value = 510) Prematurity (neonates and infants) Preoperative Factors • Preoperative/Preprocedural mechanical circulatory support (IABP, VAD, ECMO, or CPS) c • Shock, Persistent at time of surgery • Mechanical ventilation to treat cardiorespiratory failure • Renal failure requiring dialysis and/or Renal dysfunction • Preoperative neurological deficit • Any other preoperative factor (except ‘Other preoperative factors’ with code value = 777) d a Modeled as a piecewise linear function with separate intercepts and slopes for each STS-defined age group (neonate, infant, child, adult). b The model adjusts for each combination of primary procedure and age group. Coefficients obtained via shrinkage estimation with The Society of Thoracic Surgeons–European Association for Cardio-Thoracic Surgery (STS-EACTS [STAT]) Mortality Category as an auxiliary variable. c CPS = cardiopulmonary support; ECMO =extracorporeal membrane oxygenation; IABP = intraaortic balloon pump; VAD = ventricular assist device d Any other preoperative factor is defined as any of the other specified preoperative factors contained in the list of preoperative factors in the data collection form of the STS Congenital Heart Surgery Database, exclusive of 777 = ‘Other preoperative factors’.
  • 34. • All index cardiac operations in the STS-CHSD (January 1, 2010–December 31, 2013) were eligible for inclusion. • Isolated PDA closures in patients <2.5kg were excluded, as were centers with >10% missing data and patients with missing data for key variables. STS Congenital Heart Surgery Database Mortality Risk Model
  • 35. 52,224 operations from 86 centers were included STS Congenital Heart Surgery Database Mortality Risk Model
  • 36. Model Covariates Development Sample C-Stat Valida.on Sample C-Stat 1 STAT Levels C = 0.772 C = 0.787 2 STAT Levels + age and weight C = 0.818 C = 0.817 3 STAT Levels + age and weight + pa,ent factors C = 0.862 C = 0.852 4 Primary procedure + age and weight C = 0.846 C = 0.831 (Final Model) Primary procedure + age and weight + pa,ent factors C = 0.875 C = 0.858 STS Congenital Heart Surgery Database Mortality Risk Model
  • 37. Model Covariates Development Sample C-Stat Valida.on Sample C-Stat 1 STAT Levels C = 0.772 C = 0.787 2 STAT Levels + age and weight C = 0.818 C = 0.817 3 STAT Levels + age and weight + pa,ent factors C = 0.862 C = 0.852 4 Primary procedure + age and weight C = 0.846 C = 0.831 (Final Model) Primary procedure + age and weight + pa,ent factors C = 0.875 C = 0.858 STS Congenital Heart Surgery Database Mortality Risk Model
  • 38. Model Covariates Development Sample C-Stat Valida.on Sample C-Stat 1 STAT Levels C = 0.772 C = 0.787 2 STAT Levels + age and weight C = 0.818 C = 0.817 3 STAT Levels + age and weight + pa,ent factors C = 0.862 C = 0.852 4 Primary procedure + age and weight C = 0.846 C = 0.831 (Final Model) Primary procedure + age and weight + pa,ent factors C = 0.875 C = 0.858 STS Congenital Heart Surgery Database Mortality Risk Model
  • 39. Model Covariates Development Sample C-Stat Valida.on Sample C-Stat 1 STAT Levels C = 0.772 C = 0.787 2 STAT Levels + age and weight C = 0.818 C = 0.817 3 STAT Levels + age and weight + pa,ent factors C = 0.862 C = 0.852 4 Primary procedure + age and weight C = 0.846 C = 0.831 (Final Model) Primary procedure + age and weight + pa,ent factors C = 0.875 C = 0.858 STS Congenital Heart Surgery Database Mortality Risk Model
  • 40. Model Covariates Development Sample C-Stat Valida.on Sample C-Stat 1 STAT Levels C = 0.772 C = 0.787 2 STAT Levels + age and weight C = 0.818 C = 0.817 3 STAT Levels + age and weight + pa,ent factors C = 0.862 C = 0.852 4 Primary procedure + age and weight C = 0.846 C = 0.831 (Final Model) Primary procedure + age and weight + pa,ent factors C = 0.875 C = 0.858 STS Congenital Heart Surgery Database Mortality Risk Model
  • 41. Model Covariates Development Sample C-Stat Valida.on Sample C-Stat 1 STAT Levels C = 0.772 C = 0.787 2 STAT Levels + age and weight C = 0.818 C = 0.817 3 STAT Levels + age and weight + pa,ent factors C = 0.862 C = 0.852 4 Primary procedure + age and weight C = 0.846 C = 0.831 (Final Model) Primary procedure + age and weight + pa,ent factors C = 0.875 C = 0.858 STS Congenital Heart Surgery Database Mortality Risk Model
  • 42. 42 Fig 1. Distribution of hospital-specific observed-to-expected (O/E) ratios for operative mortality with 95% confidence intervals (gray lines). STS Congenital Heart Surgery Database Mortality Risk Model
  • 43. 43 Fig 1. Distribution of hospital-specific observed-to-expected (O/E) ratios for operative mortality with 95% confidence intervals (gray lines). STS Congenital Heart Surgery Database Mortality Risk Model
  • 44. 44 Fig 1. Distribution of hospital-specific observed-to-expected (O/E) ratios for operative mortality with 95% confidence intervals (gray lines). STS Congenital Heart Surgery Database Mortality Risk Model
  • 45. 45 Fig 1. Distribution of hospital-specific observed-to-expected (O/E) ratios for operative mortality with 95% confidence intervals (gray lines). STS Congenital Heart Surgery Database Mortality Risk Model
  • 46. 46 Fig 1. Distribution of hospital-specific observed-to-expected (O/E) ratios for operative mortality with 95% confidence intervals (gray lines). STS Congenital Heart Surgery Database Mortality Risk Model
  • 47. Congenital Heart Disease Meaningful Multi-institutional Outcomes Analysis Accomplishments 1)  Common Language = Nomenclature 2)  Mechanism of Data Collection (Database - Registry) 3)  Mechanism of Evaluating Case Complexity 4)  Mechanism to Verify Data Validity and Accuracy 5)  Collaboration Between Subspecialties 6)  Longitudinal Follow-Up and Linked Databases 7)  Quality Improvement Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric and Congenital Cardiac Care - Volume 1: Outcomes Analysis. Springer-Verlag London. Pages 1 – 515. ISBN: 978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online). Published in 2014.
  • 48. STS CHSD Data Verification 10% of sites audited each year Analysis of general variables –  data completeness rate of 99.94% and –  overall data agreement rate of 98.05% Analysis of mortality variables –  data completeness rate of 100% and –  overall data agreement rate of 99.09%
  • 49. Congenital Heart Disease Meaningful Multi-institutional Outcomes Analysis Accomplishments 1)  Common Language = Nomenclature 2)  Mechanism of Data Collection (Database - Registry) 3)  Mechanism of Evaluating Case Complexity 4)  Mechanism to Verify Data Validity and Accuracy 5)  Collaboration Between Subspecialties 6)  Longitudinal Follow-Up and Linked Databases 7)  Quality Improvement Barach P, Jacobs JP, Lipshultz SE, Laussen P. (Eds.). Pediatric and Congenital Cardiac Care - Volume 1: Outcomes Analysis. Springer-Verlag London. Pages 1 – 515. ISBN: 978-1-4471-6586-6 (Print). 978-1-4471-6587-3 (Online). Published in 2014.
  • 50. Jacobs JP. (Editor). 2008 Cardiology in the Young Supplement: Databases and The Assessment of Complications associated with The Treatment of Patients with Congenital Cardiac Disease, Prepared by: The Multi- Societal Database Committee for Pediatric and Congenital Heart Disease, Cardiology in the Young, Volume 18, Supplement S2, pages 1 –530, December 9, 2008.
  • 51. Collaboration Between Subspecialties Accomplishments 1)  STS Congenital Heart Surgery Database 2)  IMPACT Database of the American College of Cardiology (Interventional Cardiology) 3)  MAP-IT: Multicenter Pediatric and Adult Congenital EP Common Language = Nomenclature 4)  Pediatric Cardiac Critical Care Consortium (PC4) 5)  Congenital Cardiac Anesthesia Society Database (CCAS)
  • 52. “Science tells us what we can do; Guidelines what we should do; & Registries what we are actually doing.”
  • 53.