‘Omic’ technologies are primarily aimed at the universal detection of genes (genomics), mRNA (transcriptomics),
proteins (proteomics) and metabolites (metabolomics) in a specific biological sample.
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Biotech Era Ahead: Transcriptomics
1. Transcriptomics
Biotech Era Ahead
Under the supervision of:
Prof. Dr. Fotoh El-Domiaty
Taha A. Taha | 4th Level
Biotechnology Program
Faculty of Agriculture
Ain Shams University
2. (-ome) Omics Family
• Introduction
‘Omic’ technologies are primarily aimed at the universal detection of genes
(genomics), mRNA (transcriptomics),
7. • 1 May 2008
• 2 May 2008
• 18 May 2008
Nagalakshmi andWang et al., Science | Online: 5/1/2008 In
print:6/6/2008: TheTranscriptional Landscape of theYeast
Genome Defined
Lister, O’Malley,Tonti-Filippini et al., Cell | Online: 5/2/2008 In
print: 5/2/2008: Highly Integrated Single-Base Resolution Maps
of the Epigenome in Arabidopsis
Wilhelm and Marguerat et al., Nature | Online: 5/18/2008 In
print:6/26/2008: Dynamic repertoire of a eukaryotic
transcriptome surveyed at single-nucleotide resolution
• First Published Papers on Transcriptomics:
8. •
Dictiona
ry:
•
Glossar
y:
Transcriptomics: The study of the RNA transcripts of a
cell, tissue, or organism (i.e. the transcriptome).
Transcriptomics is concerned with determining how
the transcriptome, and hence pattern of gene
expression, changes with respect to various factors,
such as type of tissue, stage of development,
hormones, drugs, or disease. It complements and
overlaps with proteomics.
Transcriptome: The complete complement of mRNA
molecules generated by an organism or cell type.
• Definition