Here are a few famous researchers and celebrities that had their DNA sequenced.
By 2007, individuals began to have their genomes sequenced, and speak and write about it. Dr. Venter was first, his genome presented in PLoS Biology. He pondered the implications at the American Society of Human Genetics annual meeting a year later. Dr. Venter learned from his genome sequence that he has blue eyes and a tendency toward antisocial behavior, substance abuse, and novelty seeking. He found out he’s a fast caffeine metabolizer. “I can have two double lattes and wash it down with a Red Bull and not be affected by it,” he snarkily told the crowd. He also learned of elevated risk for Alzheimer disease and cardiovascular disease.
Next came James Watson, PhD, of double helix fame and first head of the human genome project. He discussed his genome at the 12th International Congress of Human Genetics in Montreal in October 2011. Dr. Watson learned he was a slow metabolizer of antipsychotics and beta blockers. His son nearly died from an antipsychotic. “So I now know that if I go psychotic, I can’t take those drugs.” And he learned why beta blockers for an irregular heartbeat knocked him out. He switched drugs.
Ron Crystal, chairman of genetic medicine at Weill Cornell Medical College, had his genome sequenced to provide a control in a project to sequence the genomes of the people of Qatar. He discovered a mutation that explained his heavy bleeding following an injury from rappelling off a frozen waterfall a few years ago. He also discovered Viking roots, a recessive disease of children, and confirmed his baldness. But he voiced fears: his family learning things they didn’t want to know, even someone using his DNA sequence to frame him for a crime or to clone him.
Dr. Ron Crystal isn’t the only one to cite potential repercussions of knowing one’s genome sequence. Said Seong-Jin Kim, the first Korean to have his genome sequenced, and that of his wife and two daughters. “Genetic disease in Korea is thought to disgrace families, and so it’s difficult to convince families with diseases to be sequenced.” A bad result could be regarded as a curse. But he was interested in using sequencing to better understand gastric cancer, which is the most common form in Asia. “Did it change attitudes? After we released our sequence, the number of sequencing companies increased.”
Steve Jobs (CEO of Apple) and Christopher Hitchens (famous author) had their cancer genomes sequenced, pancreatic and esophageal, respectively, and the information guided drug choices. (Steve Jobs died of pancreatic cancer – Christopher Hichens died of esophageal cancer) Henry Louis Gates Jr. (Host of Finding Your Roots) had his done to trace his ancestry. Glenn Close (Actress) reportedly did it to better understand mental illness in her family,
Would you want your genome sequenced? Why or why not.
BUSI 505
Research Project: Annotated Bibliography Assignment Instructions
Overview
After choosing a to ...
Measures of Central Tendency: Mean, Median and Mode
Here are a few famous researchers and celebrities that had their D
1. Here are a few famous researchers and celebrities that had their
DNA sequenced.
By 2007, individuals began to have their genomes sequenced,
and speak and write about it. Dr. Venter was first, his genome
presented in PLoS Biology. He pondered the implications at
the American Society of Human Genetics annual meeting a year
later. Dr. Venter learned from his genome sequence that he has
blue eyes and a tendency toward antisocial behavior, substance
abuse, and novelty seeking. He found out he’s a fast caffeine
metabolizer. “I can have two double lattes and wash it down
with a Red Bull and not be affected by it,” he snarkily told the
crowd. He also learned of elevated risk for Alzheimer disease
and cardiovascular disease.
Next came James Watson, PhD, of double helix fame and first
head of the human genome project. He discussed his genome at
the 12th International Congress of Human Genetics in Montreal
in October 2011. Dr. Watson learned he was a slow metabolizer
of antipsychotics and beta blockers. His son nearly died from an
antipsychotic. “So I now know that if I go psychotic, I can’t
take those drugs.” And he learned why beta blockers for an
irregular heartbeat knocked him out. He switched drugs.
Ron Crystal, chairman of genetic medicine at Weill Cornel l
Medical College, had his genome sequenced to provide a control
in a project to sequence the genomes of the people of Qatar. He
discovered a mutation that explained his heavy bleeding
following an injury from rappelling off a frozen waterfall a few
years ago. He also discovered Viking roots, a recessive disease
of children, and confirmed his baldness. But he voiced fears: his
family learning things they didn’t want to know, even someone
using his DNA sequence to frame him for a crime or to clone
him.
Dr. Ron Crystal isn’t the only one to cite potential
repercussions of knowing one’s genome sequence. Said Seong-
Jin Kim, the first Korean to have his genome sequenced, and
2. that of his wife and two daughters. “Genetic disease in Korea is
thought to disgrace families, and so it’s difficult to convince
families with diseases to be sequenced.” A bad result could be
regarded as a curse. But he was interested in using sequencing
to better understand gastric cancer, which is the most common
form in Asia. “Did it change attitudes? After we released our
sequence, the number of sequencing companies increased.”
Steve Jobs (CEO of Apple) and Christopher Hitchens (famous
author) had their cancer genomes sequenced, pancreatic and
esophageal, respectively, and the information guided drug
choices. (Steve Jobs died of pancreatic cancer – Christopher
Hichens died of esophageal cancer) Henry Louis Gates Jr. (Host
of Finding Your Roots) had his done to trace his ancestry.
Glenn Close (Actress) reportedly did it to better understand
mental illness in her family,
Would you want your genome sequenced? Why or why not.
BUSI 505
Research Project: Annotated Bibliography Assignment
Instructions
Overview
After choosing a topic, you will complete the Research
Project:Annotated Bibliography Assignment using the Research
Project: Annotated Bibliography Template provided. This
assignment will be used as a springboard for your research. It
may also be used to begin to explore ideas or concepts you find
interesting within the realm of the topics covered in this class.
Instructions
You must use the Jerry Falwell Library Research Portal and
identify a minimum of 10 scholarly journal articles from peer -
reviewed journals addressing your topic. All references must be
less than 10 years old. Ensure that the document follows current
APA format. When using the provided template, delete the
3. placeholder material and replace it with your own material.
Refer to the Grading Rubric for additional project insights.
You are required to read all instructor feedback and implement
it on future assignments.
The template will provide the layout of the assignment. Once
you have researched and selected your references, the following
should be included in the Annotated Bibliography:
· A brief statement regarding the author and his/her credentials
as an authority.
· A crisp statement regarding the relevance of this article for
your topic.
· A salient or meaningful quote from the article that you would
likely cite if you were to write an essay on this topic.
(Do not include the above criterion prompts in your final
document—it is provided here only for instructional purposes.
Your paper will have the above title and start with the below
section.)
The Research Project:Annotated BibliographyTemplate provides
examples on how the assignment to look. Ensure that you take
heed to how the references and the Research Project:Annotated
Bibliography is structured.
BUSI 505
Running head: ANNOTATED BIBLIOGRAPHY
1
Research Project: Annotated Bibliography Template
Criterion prompts to include in the Annotated Bibliography
content:
· A brief statement regarding the author and his/her credentials
as an authority.
4. · A crisp statement regarding the relevance of this article for
your topic.
· A salient or meaningful quote from the article that you would
likely cite if you were to write an essay on this topic.
(Do not include above criterion prompts in your final
document—it is provided here only for instructional purposes.
Your paper will have the above title and start with the below
section.)
Annotated Bibliography
(Name)
Liberty University
Statement of Topic
Kiyonaga (2004) suggests that, “the aging of the largest
generation the United States has ever known will affect every
social institution from employment to health care. Precisely
what the impact will be is, like all future events, still a matter
of prediction. That there will be a major impact is not” (p. 357).
This paper will seek to provide a perspective on the aging of the
workforce with specific attention given to; the potential roles
available for the aging worker, the training available and
offered the aging worker, explore implications for the
organization and finally the role the strategic HR function plays
in propelling the organization forward in dealing with this
issue.
Kondrasuk, A., Moore, H.L., & Wang, H. (2001). Negligent
hiring: The emerging
contributor to workplace violence in the public sector. Public
Personnel
Management, 30(2), 185. Retrieved from
http://proquest.umi.com/pqdlink?did=74623315&Fmt=2&client I
5. d=20655&RQT=309&VName=PQD
This article contributes significant and relevant statistics which
confirm the pervasiveness of violent incidents in general. The
National Institute of Occupational Safety and Health (NIOSH)
found that 20 persons were murdered at work every week.
Nationally, homicide is the second highest overall cause of
workplace-related deaths; for female workers, homicide is the
leading cause of workplace deaths. Workplace violence now
accounts for 15 percent of the more than 6.5 million violent acts
experienced by U. S. residents who are age 12 or older. (para
7). Kondrasuk provides information also related to a suggested
cause or contributor to the violence – negligent hiring practices.
Numerous suggestions are given throughout the materials
researched for the paper, giving additional thought to the causes
of workplace violence. However, Kondrasuk gives weight to not
only a passing platitude, but supports the concept of negligent
hiring with law and concurrent tort law claims.
Smith, S. (2002). Workplace violence. Professional Safety,
47(11), 34. Retrieved from
http://proquest.umi.com/pqdlink?did=239545531&Fmt=2&client
Id=20655&RQT=309&VName=PQD
Smith (2002) gives critical analysis to the topic of workplace
violence and highlights how ill prepared most U.S. companies
are when faced with the reality of violence. In the research, she
provides several real world examples of workplace violence, the
behavioral backgrounds and pre-incident behaviors of the
employees committing the violent acts. Smith (2002) further
contends that, “employers have both a legal duty and moral
obligation to provide a safe workplace” (p. 39). In addition to
this insight the article contributes to the impact, causes and
prevention of workplace violence. The suggestions are pliable
to most any organization.