Revolutionizing Drug Development to Improve Patients Lives
•Download as PPTX, PDF•
1 like•369 views
This document discusses Roche's efforts to revolutionize drug development in order to improve patients' lives. It details Sean's story as motivation for change and describes how Roche is building momentum by connecting with outside partners and within through increased employee engagement. Roche aims to empower patients and partner with others to be part of the healthcare solution.
Recommended
Recommended
More Related Content
Recently uploaded
Recently uploaded (20)
Featured
Featured (20)
Revolutionizing Drug Development to Improve Patients Lives
- 1. Revolutionizing Drug Development to Improve Patients’ Lives
- 2. imagine
- 3. Sean’s Story
- 6. 3 Questions Tapping Our Greatest Resource 524 Ideas 10,291 Votes 1,242 Users
- 7. Connecting with the Outside World
- 8. 2014 Connecting in New Ways 2013 Developing Solutions 2012 Engaging Ourselves Changing Our Work – and Our Impact 60 Teams 200 Awards 2011 Why Change
- 9. We Are All Sean
- 10. Be Part of the Healthcare Solution Empower Yourself Learn more about your options Join an online patient community Participate in clinical trials near you Share your story Learn about our latest R&D investments: www.roche.com/research_and_development.htm Find clinical trials: www.roche-trials.com Contact us: www.roche.com/contact.htm Partner with Roche
Editor's Notes
- I want to thank you for this wonderful opportunity to tell our story of how we are THINKING BIG and changing the course of medicine and healthcare for each one of us in the room. There are three things I want you to get out of my story: The world has changed. We at Roche, and with our patients and partners, are changing and adopting new ways of working. We need your help to be part of the healthcare revolution.
- Imagine a world where healthcare is focused on real people, like you and me – not just abstract patients. Where drugs go beyond safety and regulatory standards to enable patients to live full lives. Where healthcare solutions are personalized. And where patients have a say and a voice in the development and access to their solutions anywhere, anytime. Imagine health and healthcare integrated into our lives. This is our story.
- Two years ago, we started working with a patient named Sean Ahrens. Sean is a patient with a chronic illness - Crohn’s disease. He’s had Crohn’s disease since his early teenage years. If you were Sean five years ago, you were not as empowered as we are today to take charge of your health. You had to deal with lots of doctors, and it was tough to reduce or eliminate your symptoms so that you could function as a normally healthy person. Your best options were surgery, diet, or joining a clinical trial that might or might not be close to your home. To combat the lack of information and to help manage his disease, Sean took matters into his own hands. He started to connect with other Crohn’s patients. To do this, he started up his own website called Crohnology. We met Sean two years ago when we were embarking on our own journey of redesigning how we conduct clinical trials, interface and connect with patients, and improve the value of our medicines. Today, Sean’s site is helping many other patients living with Crohn’s. Sean is also helping us in many ways to revolutionize drug development. So how is he helping us? Sean started by joining our Innovation Advisory Board which consists of patients, physicians, drug developers, payers and leaders from other industries who have experience making large scale shifts in their business with the customer in mind. His advice and guidance has been invaluable to us, insuring we are designing patient solutions with the patient front and center in our design process. Sean is also active in working with our Imaginarium Labs and Global Development Teams who design and develop solutions for Crohn’s patients. One of our focal points is to completely restructure our trials so that we are able to come to the patient rather than have the patient come to the drug trial. For Crohn’s patients this means a lot. They don’t want to travel more than 30 minutes from home or wait in the doctor’s office for more than 30 minutes. We learned from Sean that bringing a nurse to him instead to administer his medication and check on him made his life so much easier. Hearing what is important to Sean and other patients has motivated us to continue to pursue new ways of working and thinking. These patients have helped us realize that people need and want drugs that are beyond safe and compliant. Just like Sean, and just like you and me, what they want is to be normal. To not have to worry about being close to home all the time, to be able to eat normal food, hang out with their friends. They want freedom. Looking at our mission through our patients’ eyes has given us a whole new dimension and sense of purpose. This goal is what drives our efforts day in and day out.
- But let’s take a step back to about a year before meeting Sean, when our innovation journey began. The perfect storm was brewing in healthcare, and external factors were changing the landscape we had known for so long: the pace of change and use of technology were accelerating; health care costs were skyrocketing; patients and doctors were empowering themselves and becoming more vocal participants in health and wellness; and payers and governments were shifting their views on drug priorities and value. The world was changing all around us. And we had not really changed how we designed and developed drugs in a long time. It became clear that if we wanted to stay in the game – that is, to stay valuable, relevant, and ahead of the curve – we had to change our game. And so, we began looking at our business upside down, placing the patient in the driver seat of our drug development efforts.
- We decided to take action in two areas: Revolutionize and revamp how we do our work at Roche, and in particular the Product Development organization. Reach out and work with others in new ways to co-create the future of healthcare and medicine. These ideas are not necessarily revolutionary but they have really helped a big company like ours move faster and accelerate the impact we’re having in the world and society.
- First, we reached out internally to our own employees throughout the company and around the world. We knew we needed to make this change together. It started with us designing our first crowdsourcing campaign, called RETHINK D, to help us solve three big questions: How do we access information better? How do we think differently about our patients? And, how do we stay current? The response was truly overwhelming: 500 ideas and 10,000 votes. We ended up picking three big ideas: How do we create an environment that makes it simple and easy for us to do our work, How do we understand and work with patients to bring the trials to them and, How do we set up a HUB that enables us to create an environment where we can regularly test new ideas and concepts that might be useful in the redesign of our work. The culture change has been the toughest part of the journey. To tackle this major shift, we looked at what new behaviors we needed in our organization: risk taking, fostering creativity, courage, and innovation. We also set up a recognition and reward program to highlight the ways our teams are changing the way we work. The past two years have been all about getting great ideas out, testing them and engaging ourselves in this new way of working. The next two are about integrating the high impact shifting ideas into our team and how we do our work, which includes working with people like Sean.
- At the same time that we reached out to employees, we also looked outside and talked to other companies; we asked for help. We used an Open Innovation Platform to engage with patients, and other solution seeker and finders; we created channels for real time advice from physicians - even sharing our intellectual property in some cases - all of which were unprecedented in our industry. As a result, we built a series of dynamic collaborations, consortiums and councils, maximizing the collective impact of our industry solutions and capabilities along with an even more involved set of internal and external advisors working with us on the next phase of our innovation journey with our patients.
- Roche has always been a leader in medicine. Today, we are a key part of changing the course of medicine. In 2013 alone, we have had 60-plus teams across the company trying out different innovations, doing things differently. Today we have given out over 200 awards to teams and individuals. And we regularly follow up by sharing their impact and their stories (not our story). We are using Design Thinking to increase our empathy and really understand our stakeholders’ needs, building new relationships with regulators, payers and physicians, and keeping our decisions focused on patients. We are tackling some of the most pressing issues our patients have identified, such as ease of patient participation, bringing trials to them and using new ways, including biosensors and apps, to support and enable them to maintain and manage their healthcare experience. We already have a few remote participation trials started. Who else is working with us on some of our projects? The FDA. They are a key partner to us looking at how we enable patients to participate anywhere, any place (in the US, as the first step). Next step – The world. Our goal is to conduct quick, cost-effective experiments, learn from them, share the knowledge, and iterate our process so that it becomes standard practice of care and clinical studies. What has been the impact so far? Happier patients, satisfied payers, educated government agencies and we – well, we are excited that we are meeting unmet medical needs; after all, each of us is also a patient in one form or another. Oh, and by the way, our costs to produce a new molecule or patient solution are heading down as well – our divisions have already decreased our costs by 15% in less than two and half years! Our goal is to bring costs down by 50% in 2020. We still have a ways to go and we are going to persevere to make it happen.
- The bottom line is that we are all Sean. We are all patients, employees, payers, physicians. And we need your help. We need you to get involved. To take action. To reach out, educate and empower yourself. Join digital wellness communities. There are limitless new resources available for all healthcare issues. Websites like smartpatients, patientslikeme, and clinicaltrials.gov give you knowledge and access to support systems, tips, tools, and cutting edge clinical trials close to you. Test and try things out. Your involvement will give you the power to make informed decisions and benefit from critical, life-saving knowledge and opportunities. As a consumer, you will have a say in the drugs that are developed for your well-being. Partner with pharmaceutical companies to help us take into account your individual needs and experience. Last year I helped my sister in law, diagnosed with a rare cancer, access a Roche clinical trial. Today she is cancer free, which is short of a miracle. No one can do this alone. We are all part of the healthcare challenge. And part of the solution.