This document discusses the relationship between architecture and autism. It introduces the Autism ASPECTSSTM design index, which is a framework consisting of seven design principles for creating architectural environments that are supportive for individuals with autism. These principles are acoustics, spatial sequencing, escape, compartmentalization, transition spaces, sensory zoning, and safety. The index was used to develop design criteria for a school for autism in Egypt called the Advance Center for Special Needs. The document provides background on research relating the sensory environment to autistic behavior and debates different approaches to designing for autism. It also describes how the Autism ASPECTSSTM index was created based on identifying common sensory challenges for individuals with autism.