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MEDICAL
ELECTRONICS
EC8073
Faculty Handled By:
Mrs.P.Sivalakshmi AP/ECE
Section: A & B
FIFTH SEMESTER-III YEAR- (2019-2023 BATCH)
SESSION:4
DATE: 31.08.2021
UNIT I- ELECTRO-PHYSIOLOGY AND BIO-POTENTIAL RECORDING
• Sources of bio medical signals
• Bio-potentials
• Bio potential electrodes
• Biological amplifiers
• ECG-Electrocardiogram (ECG or EKG)
• EEG- Electroencephalogram (EEG)
• EMG-Electromyography
• PCG-Phonocardiogram
• Typical waveforms and signal characteristics
Electro-Physiology
RECAP
RECAP
RECAP
SIMULATION OF ACTION POTENTIAL
https://phet.colorado.edu/sims/html/neuron/latest/neu
ron_en.html
RECAP
RECAP
BIO SIGNAL
AMPLIFIERS
OPERATIONAL
AMPLIFIERS
ISOLATION
AMPLIFIERS
INSTRUMENTATIONAL
AMPLIFIER
BRIDGE AMPLIFIERS
LINE DRIVING
AMPLIFIERS
CURRENT AMPLIFIERS
CHOPPER AMPLIFIERS
RECAP
GOLDMAN–HODGKIN–KATZ (GHK) EQUATION:
To calculate the electrical equilibrium potential across the cell's membrane
in the presence of more than one ions taking into account the selectivity of
membrane's permeability. The magnitude of membrane potential is
determined by
GOLDMAN–HODGKIN–KATZ (GHK) EQUATION:
where
E is the potential difference of an ion between membranes
R is the universal gas constant; R = 8.314471 J mol-1
T is the thermodynamics temperature, in Kelvin; 0 K = -273.15oC
z is the number of moles of electrons transferred between membranes (defined by the Valency of ion)
F is the Faraday's constant; F = 96,485.3415 C mol-1
PX is the permeability of the membrane to a particular ion (X)
[X]o is the concentration of ion outside the membrane
[X]i is the concentration of ion inside the membrane
According to Goldman’s equation Resting Potential is -86.8 mV
Recording
Potentials
• Parts of the organ.
• Functionality.
• Recording the Action potential.
• Electrocardiograph
• Normal & Abnormalities-graph.
MEDICAL ELECTRONICS_EC8073_Unit 1 session 4
MEDICAL ELECTRONICS_EC8073_Unit 1 session 4
MEDICAL ELECTRONICS_EC8073_Unit 1 session 4

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MEDICAL ELECTRONICS_EC8073_Unit 1 session 4