How did Meselson and Stahl distinguish between semiconservative and dispersive replication in their experiment? After two rounds of replication, only mixed DNA molecules were present in the gradient. After one round of replication, only mixed DNA molecules were present in native gradients. After two rounds of replication, both heavy and light DNA molecules were present in the gradient. After two rounds of replication, only heavy DNA strands were present in alkaline gradients. After one round of replication, both heavy and light DNA single-strands were present in alkaline gradients. .