Introduction to general Veterinary Pathology, Gross examination description, How to describe lesion while doing Gross/ macroscopic examination, Postmortem lesion description at basic leve

1. LECTURE NO.1
Veterinary General Pathology 301
Practical Class

2. Learning Outcomes
• By the end of the lecture you should be able to:
• Define Pathology in two ways
• Define General Pathology
• Discuss about the Morphological Changes
• Explain lesion and types of the Lesion
• Define Gross examination and Histopathology
• How to describe the Lesion in Gross examination

3. Introduction to Pathology
•Pathology:
• Pathology is the study of Disease.
• Pathos – suffering, disease
• Logos – study
Disease?
*loss of ease
*a departure from a
normal state
The better we understand the disease, the better we
can diagnose & treat it

4. What‘s normal (When Body At Ease)
Anatomy
Physiology
Histology
Biochemistry
Genetics
Health is a state of an
individual living in
complete harmony with
his environment.

5. Pathology is the study of molecular, biochemical,
functional, & morphological changes in cells,
tissues, or organs in response to an INJURY
Let’s define again
Cell damage is cell injury

6. Agents that cause things to go wrong/ injury
Trauma
Microbial
Nutritious
Genetic
Chemicals
Parasitic

7. Courses
GeneralVet.
Pathology
SystemicVet.
Pathology
Clinical
Pathology
Necropsy
Practices
&
Meat
inspection
Poultry
Pathology

8. Pathology
General
Pathology
Concerned with the
basic reactions of
cells and tissues to
injurious stimuli
Systemic
Pathology
The application of
these basic reactions
to the various body
systems, or to various
specific diseases

9. Pathology
Clinical
Pathology
It includes certain laboratory
methods which help in making
the diagnosis e.g. urine
examination, blood
examination
Necropsy
& meat
inspection
Postmortem examination of
animals.
To determine the health of
animals both prior to death
(ante mortem) and after death
(post mortem)

10. Pathology covers Four aspects of a disease
process
Etiology ( cause of disease)
Pathogenesis
Morphological Changes (Lesions)
Clinical significant / Functional
Consequence
General/Systemic
Pathology
Practical

11. Morphological Changes (Lesion)
The structural
alterations in cells or
tissues
A lesion is any
damage or abnormal
change in the tissue
structure of an
organism, usually
caused by disease
Morphology study of forms and structures

12. Types of Lesion
Macroscopic or Microscopic morphological alteration occurring
in the tissue structure or function as the result of injury
Macroscopic or Gross Lesions
Can see through the naked eye
Gross Examination
Examination of tissue without
the help of a microscope
Microscopic or histopathology
Lesions
Can see through a microscope
Histopathology
Study of diseases tissue under a
microscope
Let’s define again the lesion

13. GROSS EXAMINATION

17. Multifocal Lesions
Aborted Pig fetus
Lamb’s Liver

18. Locally Extensive

33. Describe the lesions in liver

34. Describe the lesions in Proventriculus and Gizzard of the bird

35. Revisiting Learning Outcomes
• By the end of the lecture you should be able to:
• Define Pathology in two ways yes/no
• Define General Pathology yes/no
• Discuss about the Morphological Changes yes/no
• Explain lesion and types of the Lesion yes/no
• Define Gross examination and Histopathology yes/no
• How to describe the Lesion in Gross examination yes/no