2. Histology of testis
• Testis is covered by
---tunica vaginalis
----tunica albuginea
----tunica vasculosa
• Tunica albuginea- is a thick white fibrous connective tissue—called
capsule of testis
• Deep to the capsule ,, there is tunica vasculosa– which is a highly
vascularised connective tissue.
• Septa from tunica albuginea divide testis into 200 to 300 lobules
• Each lobule contains 1- 4 seminiferous tubule
• Between the seminiferous tubules ,, there is loose connective
tissue k/a interstitial tissue & blood vessels
6. seminiferous tubule-
• Sperm producing tubule
• Convoluted and long
• About 30-70 cm long & 200 micro-metre in
diameter
• Surrounded by connective tissue [lamina
propria]----consists of flattened or spindle
shaped myoid cells
• Myoid cells are contractile in nature & help
spermatozoa to move through seminiferous
tubules.
7. ......seminiferous tubule-
• Tubule is lined by stratified cuboidal epithelium
• Tubule contains--------
i) ----spermatogenic cells
[ in different stages of spermatogenesis]
ii) ---Supporting cells of sertoli
8. spermatogenic cells
Spermatogenic cells in 4
successive stage—
--spermatogonia,
--primary spermatocyte
--secondary
spermatocyte
---spermatids.
• --primary spermatocyte
are the largest cells
10. supporting cell of sertoli
* supporting cell of
sertoli – also K/A
sustentacular cell.
*Tall columnar cell
* Its lateral process
form a tight junction
k/a BLOOD TESTIS
BARRIER
protects secondary
spermatocyte,
spermatids &
spermatozoa from
immune attack
12. Function of sertoli cells
• Provide mechanical support
• Provide nutriton to Spermatogenic cells
• Form blood testis barrier
• Secrete androgen binding protein
• Synthesize antimullerian hormone
• Do phagocytosis of residual body,, degenerating
Spermatogenic cells
13. Interstitial tissue
• occupies space b/w the
seminiferous tubules
• consist of
-- Loose connective tissue &
-- interstitial cells of Leydig
(OVAL CELL).
• It forms endocrine part of
testis
• Secrete testosterone & a
little estrogen
14. low power /T.S. of
testis tunica
albuginea
tunica vasculosa
seminiferous tubule
spermatogenic cells
&
Sertoli cell
Leydig cells
septa
17. pathway of sperm from seminiferous
tubule
seminiferous tubules
[highly coiled] in each
lobule
join to form 20 to30
straight tubules
they anastomose to form
network of tubules
called the RETE TESTIS
gives rise to 12to30
EFFERENT DUCTULES
which emerge near the
upper pole
and enter the Epididymis
18. epididymis
1. Highly coiled muscular
tubule
2. 6 meter long, made up
of smooth muscle
3. smooth muscle arranged
in circular pattern
4. is lined by
pseudostratified
columnar epithelium
with stereocilia.[non-
motile cilia]
5. Can store sperms for
several months
6. Continues as ductus
(vas) deferens
smooth
muscle pseudostratifi
ed columnar
epithelium
stereocilia
sperm
in lumen
T.S. OF epididymis
connective
tissue
30. seminiferous tubule….
• b> supporting cell of
sertoli – also K/A
sustentacular cell.
• Tall columnar cell
• Its lateral process form
a tight junction k/a
BLOOD TESTES BARRIER
protects secondary
spermatocyte, spermatids &
spermatozoa from immune
attack
31. epididymis
1. Highly coiled mucular
tubule
2. 6 meter long, made up
of smooth muscle
3. smooth muscle arranged
in circular pattern
4. is lined by
pseudostratified
columnar epithelium
with stereocilia.[non-
motile cilia]
5. Can store sperms for
several months
6. Continues as ductus
(vas) deferens
smooth
muscle pseudostratifi
ed columnar
epithelium
stereocilia
sperm
in lumen
T.S. OF epididymis
connective
tissue