This document contains the table of contents for a mycology lecture series covering various fungal and yeast infections. The series is divided into multiple sessions of varying lengths, labeled "Mycology (long)", "Mycology (short)", etc. Topics include cases of specific fungal infections, overviews of diagnostic methods and treatment options, and schemes for identifying different types of fungi in the laboratory. The table of contents lists the topics to be covered in each session, including cases of particular fungal diseases and reviews of relevant clinical information.
2. 1. Mycology (long) •Virtual Tour/Overview of Microbiology &
Virology Labs at MCC
•Osler course Two-Hour Review Lecture
•Overview: Mycology Laboratory
•Overview: Fungal Stains & technical aspects of
fungal diagnosis
•Overview: Scheme for identification of molds in
the Mycology lab
•Scheme for identifications of yeasts in the
mycology laboratory
•Yeast susceptibility testing scheme
•Cases: PHAEOHYPHOMYCETES
–Case: Fatal case of disseminated Scedosporium
apiospermum (Pseudallescheria boydii)
–Case: Fatal case of disseminated Scedosporium
inflatum
–Pharmacologic treatment options for
phaeohyphomycosis
2. Mycology (short) •Continuation PHAEOHYPHOMYCETES
–Case: Tissue diagnosis of infection by a black
mold
–Case: Dactylaria in sputum sample
3. 3. Mycology (medium) •YEASTS
–Case: Disseminated cutaneous cryptococcosis
–Case: Pulmonary cryptococcoma
–Case, extra from the medical examiner’s office:
disseminated cryptococcosis as a cause of death
–Review of Cryptococcosis; Case: C gattii
–Case: Malassezia furfur folliculitis in a bone marrow
transplant patient
–Review: Tinea versicolor and conditions caused by
Malassezia furfur
4. Mycology (short) •Continuation YEASTS
–Case: Candida sepsis by two different species of
Candida
–Statistics of Candida species prevalence at
HLMCC during the last decade
–Overview Candidiasis
–Case: Trichosporon beigelii
–Case: Blastoschizomyces capitatus
5. Mycology (medium) •HYALOHYPHOMYCOSIS:
–Case: Fatal case of fungemia by Fusarium
–Overview: hyalohyphomycosis
–Pictures: Penicillium, Scopulariopsis,
Paecilomyces
4. 6. Mycology (long) •Continuation HYALOHYPHOMYCOSIS:
–Case: Fatal case of pneumonia by Aspergillus terreus
with pulmonary nodular infarcts
–Case: Fatal case of disseminated Aspergillus fumigatus
with cavitary, necrotizing, abscess-like pulmonary
lesions with tissue drop-out
–Case: Large mycotic pseudoaneurysm of the right
pulmonary artery secondary to prior aspergillosis
–Review: pharmacologic treatment options for
aspergillosis
–Review: the concept of primary cutaneous vs
disseminated disease by fungal pathogens in cancer
patients
7. Mycology (long) •ZYGOMYCETOUS FUNGI
–Case: Pulmonary mucormycosis in a BMT patient
associated with the use of the chelating agent
deferoxamine
–Overview: Mucormycosis and the zygomycetous fungi,
and laboratory diagnostic aspects
–Case: Rhinocerebral mucormycosis in a diabetic
cancer patient
–GI Mucor Moffitt Case
–Enigma: cases in sinus biopsies
5. 8. Pneumocystosis (short) •Case: PCP pneumonia
•Overview: Laboratory diagnostic methods for PCP
•Overview: pharmacologic treatment options for
PCP
9. Mycobacteria &
Actinomycetales (very
long)
•Case: Old tuberculoma
•Overview: Diagnostic Mycobacteriology
•Case: Probable MAI as a tissue diagnosis in the
intestine of an HIV + patient
•Overview: stains for acid-fast bacilli
•Case: Disseminated Nocardia brasiliensis in a
cancer patient
7. 11. Bacteriology
(very long)
•Osler course Bacteriology Lecture + Dr Sandin’s
additional 200 slides to make it comprehensive
•Overview: Bacteriology Laboratory, new
technologies
•Case: Fatal Monomicrobial Septicemia by
Clostridium septicum
•Overview: pharmacologic treatment options for
clostridial disease
•Case: Fatal polymicrobial septicemia
•Case: Fatal case of typhlitis & review of the entity
•Overview: Scheme for identification of the 5 most
common bacterial groups in the wet Bacteriology
laboratory (Gram positive cocci catalase negative,
and catalase positive; gram positive bacilli, gram
negative bacilli, anaerobes)
12. Bacteriology
(short)
•Case: Fatal Listeria monocytogenes sepsis &
meningitis
•Overview: laboratory & clinical aspects of listeriosis
•Potpopurri: gram positive pathogens in CA patients
13. Bacteriology
(medium)
•Case: intracellular pathogen- Fatal case of Chronic Q fever
presenting as an inflammatory pseudotumor of the lung
•Overview of Coxiella burnetii and the diseases it causes
•MRSA Overview, shortened version; Legionella Plate
Rounds
8. 14. Parasitology (long) •Overview: the Parasitology section of a lab in a
cancer patient hospital
•Case: Polymicrobial empyema from disseminated
strongyloidiasis
•Overview: laboratory diagnosis of stongyloidiasis
•Pharmacologic treatment options for
strongyloidiasis
•Entamoeba histolytica
•Echinococcus granulosus
15. Parasitology (medium) •Case: Pulmonary granulomatous nodule due to
Dirofilaria immitis
•Overview: Dirofilariasis
•Cysticercosis
•MALARIA Plate Rounds
9. 16. Virology (medium) •Overview: the Clinical Virology section and lab
of a hospital
•Overview: methodology in a modern hospital
‘wet’ diagnostic virology laboratory (CP)
•The FilmArray Respiratory Viral Panel
•New CDC HIV Testing Algorithm
17. Virology (medium) •Infectious Disease Pathology (AP Virology)
18. Virology (long) •Additional overview of methods: Diagnostic
Molecular Microbiology
10. 19. Infection ‘Look-
Alikes’, Or
‘The Two Faces of
Infectious Disease
Pathology in a Cancer
Hospital Practice
•Face One: Cancers that present like infections
–Case: Colon Cancer metastatic to finger
mimicking onychomycosis with paronychia
–Overview: Infectious Causes of Digit lesions
–Case: Recurrent Lymphoma presenting as a
subcutanous foot and leg lesion
–Overview: Potpourri of skin lesions from our
cancer patient practice proven by culture to be of
an infectious origin
•Face Two: Infections that present as pulmonary
coin lesions that require rule out cancer by
thoracotomy with specimens sent to Pathology
and/or Microbiology
–Case: Old coccidioidoma
–Overview: Coccidioides immitis and
coccidioidomycosis
–Overview: Concept of Sampling Error in
diagnostic pathology
–Overview: Contributions to microbial diagnosis in
a laboratory by the ‘wet lab’ and the ‘fixed-tissue’
lab sections (clinical and anatomic pathology)
–Overview: The Pulmonary Nodule, infectious
agents that present as various types of pulmonary
coin lesions
If time allows, we will do #19 which will serve as an overview/review of some concepts already covered.