This presentation deals with circulation in human body.
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2. Materials formed in one part of the
body have to be taken up to other
parts where they are needed or to be
got rid of.This is an essential
requirement of most animals.This
function is performed by the body
fluids.
3. The functions performed by the
circulatory system in all animals are,
Transport of oxygen and nutrients
like glucose, amino acids, vitamins,
minerals to every cell.
15. Gk. Erthros – red, kytos –
cell
Circular, biconcave, non
nucleated cells
Diameter: 7 um
Thickness: 2.5 um
Red blood cell count:
Female: 4.3 to 5.2 million
per cubic mm
Male: 5.1 to 5,8 million
per cubic mm
Life span 120 days
16. Erythropoiesis
In Foetus: liver &
spleen
Adults: red bone
marrow
Polycythemia
Erythrocytopenia
17.
18. Respiratory pigment:
Haemoglobin
Transport O2 & CO2
NORMAL VALUES OF Hb:
Adult male: 13-18
gm/100 ml of blood
Adult female: 11.5-16.5
gm/100 ml of blood
Anemia
19.
20. Functions Of RBCs:
1) Transportation of O2 from lungs to
tissues and CO2 from tissues to
lungs
2) Blood ph (Hb Buffer)
3) Viscosity of blood
21. Gk. Leukos – white, kytos
– cell
Colorless, nucleated,
amoeboid & phagocytic.
Diapedesis
Size: 8-15 um
WBC count: 5000 – 9000
per cubic mm of blood
Life span: 3 - 4 days
22.
23. Leucopoiesis
Red bone marrow, spleen,
lymph nodes, tonsils,
thymus & Payer’s
patches.
Leucocytosis
Leucopenia
Pathological increase:
Leukemia (Blood cancer)
Dead WBCs
phagocytosis
35. Gk. Thrombos - clot,
kytos- clot
Non nucleated, round
and biconvex
Diameter: 2.5 – 5 um
Platelet count: 2.5 to
4.5 lakhs per cubic mm
of blood
Life span: 5-10 days
36. Fragments formed from
large cells
Megakaryocytes of
bone marrow
Thrombopoiesis
Thrombocytosis
Thrombocytopenia
47. HEART
o Middle of thoracic cavity
o Space Mediastinum
o Two lungs
o Hollow, muscular, conical
organ
o Broad base, narrow apex
o Tilted left
o Mesodermal
o 12 cms in length & 9 cms in
breadth
o 250 – 300 grams.
48.
49.
50. PERICARDIUM
o Double layered peritoneum
o Two layers:
1) Fibrous pericardium
2) Serous pericardium
a) Outer parietal layer
b) Inner visceral layer
58. Coronary artery supply oxygenated blood
Coronary vein collect deoxygenated blood
Coronary veins Coronary sinus opens in
right atrium
Note: The coronary sinus is a collection
of veins joined together to form a large
vessel that collects blood from
the heart muscle (myocardium). It
delivers deoxygenated blood to the right
atrium, as do the superior and inferior
vena cavae. It is present in all mammals,
including humans.
The name comes from the Latin "corona'
, meaning crown, since this vessel forms
a partial circle around the heart.
59.
60. Right atrium larger than
left
Right ventricle
Pulmonary trunk/ aorta
Left ventricle Systemic
aorta
Ligamentum arteriosum
Remnant of ductus
arteriosus of foetus
PULMONAR
Y TRUNK
AORT
A
LA
61. The ligamentum arteriosum (Latin: arterial ligament) is a
small ligament that is the remnant of the ductus
arteriosus formed within three weeks after birth.
In the developing fetus, the ductus arteriosus, also called
the ductus Botalli, is a blood vessel connecting the
pulmonary artery to the proximal descending aorta. It
allows most of the blood from the right ventricle to
bypass the fetus's fluid-filled non-functioning lungs.
62.
63. Four chambered (2 A, 2 V)
ATRIA
Superior, thin walled,
receiving chambers
Interatrial septum
Deoxygenated blood to
right atrium SVC, IVC,
Coronary sinus
69. A opens into V
Atrioventricular aperture Valves
R AV aperture Tricuspid valves
L AV aperture Bicuspid valve or
mitral valve
70. Valves Chordae tendinae
papillary muscles of ventricles
Function of CT:
Prevent valves turning back
into atria during contraction of
ventricles.
73. The chordae tendineae (tendinous chords), or heart
strings, are cord-like tendons that connect the papillary
muscles to the tricuspid valve and the mitral valve in
theheart.
Chordae tendinae are approximately 80% collagen,
while the remaining 20% is made up of elastin and
endothelial cells.
75. Columnae carneae:
• Muscular ridges or columns projecting from the inner walls of
the heart ventricles.
• Their structure is important to their role. Had the inner surface
of heart ventricles been flat, suction could occur and this
would impair the heart's ability to pump efficiently.
• Word origin: Latin columnae (column) + carneae (flesh)
76. Pulmonary trunk right
ventricle deoxygenated
blood lungs
oxygenation
Systemic aorta left
ventricle oxygenated
blood body
Semilunar valves = prevents
backflow of blood during
ventricular diastole
80. Ventricular systole
AV node myocardium of ventricles
Wave of contraction
Purkinje fibres
Interventricular septum
Right and left bundle of branches
AV node
81. Events associated with one heart beat.
0.8 seconds
Heart beat = Atrial systole +Ventricular
systole + Joint diastole
82. Backflow tricuspid valve
Right atrium right ventricle
AV aperture
Deoxygenated blood
Atrial systole
83. Atrial systole = 0.1 sec
Backflow bicuspid valve
Left ventricle AV aperture
Left atrium
Oxygenated blood
96. Systolic blood pressure
Ventricular systole
Maximum
Blood flow in arteries
120 mm Hg
Diastolic blood pressure
Ventricular diastole
Minimum
80 mm Hg
Normal blood pressure ;
120 / 80 mm Hg.
97.
98.
99.
100.
101.
102.
103. Graphic record =
electrocardiogram or
ECG
Instrument or ECG
machine =
Electrocardiograph
Action potentials
Father of
electrocardiography
Eithoven (1903)