3. ICELAND MI study
Shanbhag et al.,
LGE CMR group No. of patients
MI 211
Major non ischaemic fibrosis (well established classic
patterns associated with myocarditis,infiltrative
cardiomyopathies or pathological hypertrophy)
54
Minor non ischemic fibrosis ( remaining localised
patterns not meeting major criteria)
238
No LGE (reference group) 397
11.
that all-cause mortality in UMI patents was lower than
recognized MI for at least 5 years
12. All-cause mortality (A), major adverse cardiac events (B), incident nonfatalmyocardial infarction (MI) (C), and incident heart
failure (D) in participants with unrecognized MI (UMI), recognized MI (RMI), and no MI at baseline.
20. Galan-Arriola et al
increased T2 relaxation
intramyocyte oedema
Changes in T1 and the extracellular volume on T1 mapping occurred much later
and coincided with wall motion abnormalities
21.
22.
23. Asterisks indicate statistically significant statistical differences
compared with week 0 for each time point: *p < 0.05, **p < 0.01,
***p < 0.001, or nonsignificant (NS).
(A)Fibrosis (%) in the infused area for each group at sacrifice.
Representative images show Sirius Red staining.
(B) (B) ECV (%) in the infused area for each group at
sacrifice. Representative images show CMR native T1-MOLLI
with a 550 to 1,750 ms masked range. Red arrows mark areas with
significantly increased signal.
(C) Water content (normalized to dry weight) in the infused area
for each group at sacrifice. Representative hematoxylin and eosin
images are shown. Black arrows mark
intracardiomyocyte vacuolization.
(D) T2-GraSE mapping (ms) in the infused area for each group at
sacrifice. Representative images show CMR T2-GraSE mapping
with a 20 to 120 ms mask range.
Red arrows mark areas with significantly increased signal.
Abbreviations as in Figures 2 and 3.
24.
25. TAKE HOME MESSAGE
COMPETENCY IN PATIENT CARE AND PROCEDURAL SKILLS
TRANSLATIONAL OUTLOOK
52. European Heart Journal, Volume 40, Issue 25, 1 July 2019, Pages 2047–2055, https://doi.org/10.1093/eurheartj/ehz191
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