1. Historical Milestones in
Hypertension and its Management
Dr. Nagula Praveen
MD,DM
Associate Professor of Cardiology
Osmania General Hospital
Hyderabad
3. WILLIAM HARVEY
English Physician
Circulation of the Heart
and Blood
1628
STEPHEN HALES
English Clergyman
First person to
measure blood pressure
1733
RIVA ROCCI
Italian
Mercury sphygmomanometer
1896
N.C. KOROTKOFF
Russian
1905
reported on the
method of
auscultation of
brachial artery, the
method which is
widely used today.
4. The term essential hypertension ('Essentielle Hypertonie')
was coined by Eberhard Frank in 1911 to describe
elevated blood pressure for which no cause could be found.
Thomas Young -
Hypertension as a disease 1808
Malignant hypertension, a term used to describe severe
hypertension which eventually resulted in death, was first
used by The Mayo Clinic in 1928.
5. “Hypertension may be an important compensatory
mechanism which should not be tampered with, even were it
certain that we could control it”.
–Paul Dudley White, Father of Preventive Cardiology.
7. President Franklin D. Roosevelt was given a clean bill
of health by his physician even when his BP was
recorded as ~220/120.
A few years later while at Yalta, Winston Churchill’s
personal physician noted in his diary that President
Roosevelt “appeared to be have had signs of
‘hardening of the arteries disease’ and had a few
months to live.”
President Roosevelt ultimately had a fatal
hemorrhagic stroke 2 months later, and his death
brought hypertension’s potential as a deadly to the
limelight.
Three years after Roosevelt’s death, the pivotal
National Heart Act was signed into law by President
Truman. The Act created the path for the study of
heart diseases and resulted in several studies
including the Framingham Heart Study.
13. Miguel Ondetti and David
Cushman, 1975 developed
Captopril, the first of a new class of
drugs known as angiotensin
converting enzyme (ACE) inhibitors.
James Whyte Black, 1962
Developed propranolol, a beta blocker
used for the treatment of heart disease
14. I wish I had my betablockers handy
-Dr. James Black, 1988
19. Conclusion:
This study showed the clinical efficacy, safety and acceptability of the
perindopril/indapamide/amlodipine SPC in patients with grade 2/3 hypertension inadequately
controlled with two drug therapy. The clinical effectiveness was observed in more than 96%
patients. The benefit of SPC therapy in hypertension control was reconfirmed in this study.
20. Hypertension Screening on Occasion
of World Hypertension Day 2022
• Of the approximately 4500 patients screened, around 800+
patients were screened at OGH, Hyderabad.
3565
922
Males Females