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3DPRINTINGOF PHARMACEUTICALS
Presented by:-
Pradeep kumar Pal
M.Pharm (1st yr)
(Department of Pharmaceutics)
Flowof presentation
INTRODUCTIN
HISTORY
GENARAL PRINCIPLE
TYPES OF PRINTERS
3D PRINTING MATERIALS
CHALLENGES OF 3D PRINTING TECHNOLOGY
ADVANTAGES & DISADVANTAGES
APPLICATION OF 3D PRINTING
FUCTURE PROSPECTS
3D PRINTING PRODUCTS
CONCLUSION
REFERENCES
Department of Pharmaceutics 23/10/2019 2
INTRODUCTION
• 3D printing or additive manufacturing, creates
physical objects from a geometrical representation by
successive addition of materials.
 3D printing technology can print an object layer by
layer deposition of material directly from a computer
aided design (CAD) model.
323/10/2019Department of Pharmaceutics
423/10/2019Department of Pharmaceutics
523/10/2019Department of Pharmaceutics
GENERALPRINCIPLE
623/10/2019Department of Pharmaceutics
TYPESOF PRINTERS
7
NOZAL BASED
DEPOSITION SYST.
PRESSURE ASSOCIATED
MICROSYRING
HOT MELT PRINTING
1.
LASER BASED WRITING
SYSTEM
SELECTIVE LASER
SINTERING
STEREOLITHO
GRAPHY
2.
23/10/2019Department of Pharmaceutics
8
Nozzle-based deposition systems or Material extrusion: consist
on the mixing of drugs and polymers and other solid elements
prior to 3D printing. The mixture is passed through a nozzle that
definitely originates, layer by layer, the three-dimensional product.
And fused deposition modeling The melted material is deposited
layer-by-layer and fused together because the layers are in the
molten state as the build platform moves downwards until the
finished product is obtained.
1. NOZALBASEDDEPOSITIONSYSTEM
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9
2. LASERBASEDWRITING
SYSTEM
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10
SELECTIVELASERSINTERING
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11
Stereo lithography is an additive manufacturing process using a vat
of liquid UV- curable photopolymer ”resin” and a UV laser to
build parts a layer at a time.
STEREOLITHOGRAPHY
23/10/2019Department of Pharmaceutics
12
3DPRINTINGMATERIALS
METALS
• Stainless steel
• Gold
• Nickel
• Aluminium
• Titanium
• Silver
• Bronze
RESINS
• High Detail
Resins
• Paintable Resin
• Transparent
Resin
PLASTIC
• PLA
• ABS
• PC
• PVA
23/10/2019Department of Pharmaceutics
13
• Polyamide
• Alumide
CARBON FIBER POWDERS
NITINOL
GRAPHITE &
GRAPHENE
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14
CHALLENGESIN3DPRINTINGTECHNOLOGY
The technology is still under the developing stage. Hence it
undergoes several challenges such as optimization process,
improving performance of device for versatile use, selections of
appropriate excipients, post treatment method, etc.
To improve the performance of 3D printed products and to
expand the application range in novel drug delivery systems.
To achieve quality 3D Products, many important parameters
need to be optimized like printing rate, interval time between two
printing layer, distance between the nozzles and the powder layer,
etc.
23/10/2019Department of Pharmaceutics
15
ADVANTAGES
 Rapid production of prototypes.
 Low cost of production.
 No storage cost.
 Quick availability of organs.
 Manufacturing speed.
23/10/2019Department of Pharmaceutics
16
DISADVANTAGES
 Intellectual property issues
 Unchecked production of dangerous items
 Limitation of size
 Limitation of raw material
 Cost of printers
23/10/2019Department of Pharmaceutics
1723/10/2019Department of Pharmaceutics
18
FUTURE PROSPECTS
New opportunities In near future 3D printing approach will be
utilized in many ways such as –
 Fabricate and engineer various novel dosage forms,
 Achieve optimized drug release profiles,
 Develop new excipients, avoid incompatibilities between
multiple drugs,
 Drug dosage forms, supporting delivery,
 Limit degradation of biological molecules or helping to
research cures.
23/10/2019Department of Pharmaceutics
19
3D PRINTING PRODUCTS
EARPINNA HUMAN HEART
23/10/2019Department of Pharmaceutics
23/10/2019Department of Pharmaceutics 20
CONCLUSION
3D printing technology has the potential to open
doors in product development, manufacturing and
distribution for pharmaceutical companies. It
could help fulfill the promise of personalized
medicine, a concept that is growing in popularity
within the industry.
21
REFERENCES
 http://www.pharmtech.com/vision-3d-printing-pharma-
manufacturing
 http://www.pharmaceutical-journal.com/news-and-
analysis/features/3d-printing-the-future-of-manufacturing-
medicine/20068625.article
 http://en.wikipedia.org/wiki/3D_printing
Visit www.seminarlinks.blogspot.in to Download
23/10/2019Department of Pharmaceutics
2223/10/2019Department of Pharmaceutics

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3 D printing presentation