In today's competitive business environment "change" is the new normal. Organizations in any line of business have to build their capabilities to adapt and deliver timely response to changes. Building agile operations has become paramount to enable new business strategies and to adapt quickly, effectively and efficiently with changes. Changing the three key dimensions of operations processes, people and technology is a challenge. In this presentation a new framework, "Operational Agility Framework", is introduced, providing a practical and proven method to build "Agile Operation". The three key components of the framework and how to apply them through practical example will be discussed.