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Dr. Nilanjan Kar
Medical officer, national
health mission
Chemotherapy In STD
CONTENTS
Introduction
1 Common STD in India
2
Disease Burden
3 Chlamydia
4
Syphilis
5 Gonorrhea
6
CONTENTS
Genital Herpes
7 AIDS
8
Prevention of STD
9 References
10
Acknowledgement
11
Introduction
01
Definition
 STD is group of diseases that spread from person to person through sexual
contact .
 incidence : 1 in 4 teenage have STD ( western statistics )
 Female Are more effected than male
 STD in pregnancy are more dangerous and may lead to abortion , congenital
anomaly
 It is spread through
1. Sexual intercoarse
2. Oro - genital contact
3. Blood contact : IV syringe , blood transfusion
4. Vertical Transmission : mother to fetus
Common STD
in india
02
 Chlamydia : caused by chlamydia Trachomatis
 Gonorrhea : caused by Neisseria Gonorrhea
 Syphilis : caused by Trepanoma
 Genital Herpes : caused by HSV 2
 AIDS by HIV
 Hepatitis B infection
 others : Public Lice , Trichomoniasis
Disease Burden of STD
Chlamydia
4
 Azithromycin 1g single Dose
Or
Doxycycline 100 mg BD × 7 days
Alternatives :
Erythromycin 500 QDS × 7 days / Ofloxacin 300 BD × 7 days / levofloxacin 500 BD ×
7 days
Syphilis
5
For Primary, Secondary and early latent
 Inj Benzathine Penicillin G 2.4MU single dose IM
Or
 Alternatives If allergic to Penicillin : T.Doxycycline 100 mg
orally twice daily for 14 days
For Tertiary and late latent
Inj Benzathine Penicillin G 2.4 MU IM once in a week for 3 weeks
or
Alternatives If allergic to Penicillin : T.Doxycycline 100 mg orally twice daily for 28
days
Gonorrhea
6
 Cefixime 400 mg single dose
Or
 Inj ceftriaxone 125 IM single dose
+
Azithromycin 1g single dose / Doxycycline 100 mg twice for 7 days
Genital Herpes
7
 T. Acyclovir 200 mg 4-5 times daily
for 7-10 days
 Topical acyclovir cream
 Alternatives : Famicyclovir , valacyclovir
AIDS
8
 AIDS caused by HIV I , II
 it Is a very dangerous STD all over the
globe as unavailability of vaccine and lack
of complete cure
 Chemotherapy In HIV is a boon in the
medical Era as it reduce both mortality
and morbidity
 Tenofovir + Lamivudine + Efavirinez
 Zidovudine + Lamivudine + Nevirapine
 Tenofovir + Lamivudine + Nevirapine
 Zidovudine + Lamivudine + Efavirinez
Common Preferred regimens
Prevention of STD
 Abstinence: avoid sexual intercoarse
 Stay faithful : practice monogamy , avoid multiple sex partner
 Use precautions: use of condom , bacteriocidal lubricant
 Avoid alcohol , mind altering drug
 Get tested for STD regularly
 Check your partner for any sore , discharges
References
1. Textbook of preventive and social medicines , 27th Ed,2023 ,k.park , bhanot
2. Essential of medical pharmacology , 8th ed , 2018 , K.D.Tripathi , Jaypee brothers
3.https://www.who.int/
4.http://naco.gov.in/
Acknowledgement
THANK YOU

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Chemotherapy of STD.pptx

  • 1. Dr. Nilanjan Kar Medical officer, national health mission Chemotherapy In STD
  • 2. CONTENTS Introduction 1 Common STD in India 2 Disease Burden 3 Chlamydia 4 Syphilis 5 Gonorrhea 6
  • 3. CONTENTS Genital Herpes 7 AIDS 8 Prevention of STD 9 References 10 Acknowledgement 11
  • 5. Definition  STD is group of diseases that spread from person to person through sexual contact .  incidence : 1 in 4 teenage have STD ( western statistics )  Female Are more effected than male  STD in pregnancy are more dangerous and may lead to abortion , congenital anomaly
  • 6.  It is spread through 1. Sexual intercoarse 2. Oro - genital contact 3. Blood contact : IV syringe , blood transfusion 4. Vertical Transmission : mother to fetus
  • 7. Common STD in india 02  Chlamydia : caused by chlamydia Trachomatis  Gonorrhea : caused by Neisseria Gonorrhea  Syphilis : caused by Trepanoma  Genital Herpes : caused by HSV 2  AIDS by HIV  Hepatitis B infection  others : Public Lice , Trichomoniasis
  • 10.  Azithromycin 1g single Dose Or Doxycycline 100 mg BD × 7 days Alternatives : Erythromycin 500 QDS × 7 days / Ofloxacin 300 BD × 7 days / levofloxacin 500 BD × 7 days
  • 12. For Primary, Secondary and early latent  Inj Benzathine Penicillin G 2.4MU single dose IM Or  Alternatives If allergic to Penicillin : T.Doxycycline 100 mg orally twice daily for 14 days
  • 13. For Tertiary and late latent Inj Benzathine Penicillin G 2.4 MU IM once in a week for 3 weeks or Alternatives If allergic to Penicillin : T.Doxycycline 100 mg orally twice daily for 28 days
  • 15.  Cefixime 400 mg single dose Or  Inj ceftriaxone 125 IM single dose + Azithromycin 1g single dose / Doxycycline 100 mg twice for 7 days
  • 17.  T. Acyclovir 200 mg 4-5 times daily for 7-10 days  Topical acyclovir cream  Alternatives : Famicyclovir , valacyclovir
  • 19.  AIDS caused by HIV I , II  it Is a very dangerous STD all over the globe as unavailability of vaccine and lack of complete cure  Chemotherapy In HIV is a boon in the medical Era as it reduce both mortality and morbidity
  • 20.  Tenofovir + Lamivudine + Efavirinez  Zidovudine + Lamivudine + Nevirapine  Tenofovir + Lamivudine + Nevirapine  Zidovudine + Lamivudine + Efavirinez Common Preferred regimens
  • 21. Prevention of STD  Abstinence: avoid sexual intercoarse  Stay faithful : practice monogamy , avoid multiple sex partner  Use precautions: use of condom , bacteriocidal lubricant  Avoid alcohol , mind altering drug  Get tested for STD regularly  Check your partner for any sore , discharges
  • 22. References 1. Textbook of preventive and social medicines , 27th Ed,2023 ,k.park , bhanot 2. Essential of medical pharmacology , 8th ed , 2018 , K.D.Tripathi , Jaypee brothers 3.https://www.who.int/ 4.http://naco.gov.in/