Cognitive Computing: Company presentation by Avner Halperin, Co-Founder & CEO of EarlySense at the NOAH Conference 2019 in Tel Aviv, Hangar 11, 10-11 April 2019.

1. From Data to Outcomes:
Analytics and sensing for improved healthcare

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3. Deliver improved outcomes via contact-free Digital Health sensing solutions &
analytics throughout the continuum of care
The EarlySense Vision
2

4. 3
The Challenges of AI & Predictive Analytics
E. Zimlichman., E et al, Journal of Hospital Medicine. 2012, 7(8), 628–633.
Effective Medical Predictive
Analytics requires:
1. Accurate Sensing
2. Timely prediction
3. Driving intervention for
outcome improvment

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How Many Mattresses Can We Measure Through?...

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11. Response time improvement

12. Verified patient turns leaders

13. All tech issues statistics

14. Usage improvement

15. Value Proposition: Improved Clinical Results
The Implementation of The EarlySense Solution is Reported by Hospitals to Reduce These Critical
Parameters: data collected in 10 hospitals on over 10,000 patients. Sample results:
181. Based on 7,643 Patients’ Clinical Trial
2. Slight, SP et al, Society of General Internal Medicine
3. April 2013. 3. Palace, ZJ et al, AGS. May 2013
4. Zimlichman, E et al, ATS. 2012
45%
Reduction in the
number of ICU days
on patient
transferred from
med/surg4
9%
Reduction in Length
of Stay4
86%
Reduction in the
number of Code Blue
events4
43%
Reduction in the
number of Patient
Falls3
64%
Reduction in the
number of Pressure
Ulcers2

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The return on investment of implementing a continuous
monitoring system in general medical-surgical units
Cost Savings and Return On Investment model
1. Allman RM, eat al. Pressure ulcers, hospital complications, and disease severity: impact on hospital costs and length of stay. Adv Wound Care. 1999.
2. Milbrandt EB, et al. Growth of intensive care unit resource use and its estimated cost in Medicare. Crit Care Med. 2008. Health Care Utilization Project (HCUP), Nationwide Inpatient Sample (NIS), Agency for
Healthcare Research and Quality, 2008
Model
Analysis
Consideration
Savings Per
Patient
Admission
Annual
Savings
Base Case Total cost of intervention effects $710 $1,701,600
Conservative
Includes only direct variable cost
Component of final day of LOS
$224 $537,400
Slight, SP et al, Society of General Internal Medicine. 2013
Assuming 33 beds, 2,500 Patients per Unit per Year
Costs Associated for Calculation
Pressure Ulcer
$15,229 per case¹
Medical-surgical Hospitalization
$1,448 per Day²
ICU Hospitalization
$2,575 per Day²

17. Conclusions
• Early warning score tools can be used to identify low
risk patients, not just high risk patients
• A protocol of skipping overnight vital signs on low risk
nights combined with continuous monitoring is safe
and feasible
• Low risk patients on such a protocol did not have any
increased risk of adverse events and reported better
sleep and increased satisfaction with nursing care

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2018 Impact
Lives saved
3,120
(*) It is not possible to precisely determine the overall clinical and economic impact of implementing EarlySense systems globally. However, assuming that the outcome achieved in every bed is in line with the results published in
the American Journal of Medicine in relation to reduction of adverse events are applicable worldwide, it is generally estimated that by early detection and intervention, clinicians were able to impact patients and hospitals as outlined herein.
ICU days prevented
28,820
Hospital days saved
183,960
Saved by hospitals
$168,000,000
1,000,000 Patients Monitored Milestone Achieved

19. 10 Years in the Making…: Changing the Standard of Care

20. 23CONFIDENTIAL
Unique Database Creation, Leading to a Superior AI
Superior Predictive Analytics –
continuously improving due to largest
and growing cardiac/respiratory
medical grade database – HIPAA
Compliant
Personalized, predictive analytics, e.g.:
Cardiac events, apnea onset alerts
Premium service, expert advice
engine
Population trends & risk analysis
Enables ground breaking research on early
warning scoring and risk prevention tools

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Why We Do What We do
Pressure Ulcers
prevented by
clinical teams
using EarlySense12,783
Lives saved by
clinical teams
using EarlySense1,956
Patient falls
events prevented
by clinical teams
using EarlySense2,843
Code blue events
prevented by
clinical teams
using EarlySense2,445
(*) It is not possible to precisely determine the overall clinical and economic impact of implementing EarlySense systems globally. However, assuming that the outcome achieved in every bed is in line with the results published in
the American Journal of Medicine in relation to reduction of adverse events are applicable worldwide, it is generally estimated that by early detection and intervention, clinicians were able to impact patients and hospitals as outlined herein.

22. Contact Free Continuous Sensing Enables Quick and Easy Collection
of Huge Clinical Databases
Contact-free analytics delivers proven outcomes in hospitals and
post acute systems
Advanced sensing and analytics is the basis for enhanced care in low
acuity environments – the biggest opportunity in the history of
monitoring
Summary

23. THANK YOU
www.earlysense.com

24. Avner Halperin, CEO
5 Lessons Learned in Medical & Social Entrepreneurship

25. Personally Meaningful Challenge
Leverage diversity
Empower change in behavior
Deliver Measurable Impact
Run like a Marathon
5 Key Entrepreneurship Learnings:

26. § 140 women and men: PhDs, Clinicians, Engineers, Physicists, Quality professionals, Technicians, Marketing and Sales
professionals
§ Global company: 82 team members in Israel, 56 in the US
§ Diverse team:
- Ages range from 17 to 77
- 40% Women, 60% Men – team leaders and above: 52% women
- Speak 13 different native languages – software developed by secular and Haredi Jews and by Palestinians in Ramallah
§ Significant number of employees with the company for over 10 years
§ Leveraging partners diversity:
Leveraging Diversity

27. Deliver improved outcomes via contact-free Digital Health sensing solutions &
analytics throughout the continuum of care
The EarlySense Vision
33

28. 34
2018 Impact
Lives saved
3,120
(*) It is not possible to precisely determine the overall clinical and economic impact of implementing EarlySense systems globally. However, assuming that the outcome achieved in every bed is in line with the results published in
the American Journal of Medicine in relation to reduction of adverse events are applicable worldwide, it is generally estimated that by early detection and intervention, clinicians were able to impact patients and hospitals as outlined herein.
ICU days prevented
28,820
Hospital days saved
183,960
Saved by hospitals
$168,000,000
1,000,000 Patients Monitored Milestone Achieved

29. 35
Data flow

30. Value Proposition: Improved Clinical Results
The Implementation of The EarlySense Solution is Reported by Hospitals to Reduce These Critical
Parameters: data collected in 10 hospitals on over 10,000 patients. Sample results:
361. Based on 7,643 Patients’ Clinical Trial
2. Slight, SP et al, Society of General Internal Medicine
3. April 2013. 3. Palace, ZJ et al, AGS. May 2013
4. Zimlichman, E et al, ATS. 2012
45%
Reduction in the
number of ICU days
on patient
transferred from
med/surg4
9%
Reduction in Length
of Stay4
86%
Reduction in the
number of Code Blue
events4 & Mortality
43%
Reduction in the
number of Patient
Falls3
64%
Reduction in the
number of Pressure
Ulcers2

31. 10 Years in the Making…: Changing the Standard of Care

32. Delivering Hospital Proven Technology to Home
Access to medical grade technology in home environment è empowering better care by family
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Contact Free,Invisible,
Additional Sensors -
optional
Works under all mattresses
(except waterbeds)
Wirelessly communicates to
smartphone and cloud
Accurately tracks heart &
breathing patterns, motion,
stress and sleep and includes
advanced analytics
Precise - even with
2 people in bed
HIPAA Compliant
Sensing and
analytics solution
for integration with
B2B partners

33. 39CONFIDENTIAL
Increases accessibility of fertility data
and improved self managment
Key Features:
Prediction of fertility window and
Ovulation
Period tracking, prediction of next
menses day
Stress and Sleep monitoring
Future Development:
Pregnancy detection
Pregnancy monitoring
Track mother and baby
New Women’s Health Platform – Winner @ CES
First ever contact-
free fertility platform
for women
EarlySense clinical data show a significant advantage
over general physician’s and multi-month estimate
predictions of ovulation
Accurate ovulation tracking clinically proven to
increase chances of conception
Prediction of ovulation much more effective than
same day ovulation detection

34. 40CONFIDENTIAL
Unique Database Creation, Leading to a Superior AI
Superior Predictive Analytics –
continuously improving due to largest
and growing cardiac/respiratory
medical grade database – HIPAA
Compliant
Personalized, predictive analytics, e.g.:
Cardiac events, apnea onset alerts
Premium service, expert advice
engine
Population trends & risk analysis
Enables ground breaking research on early
warning scoring and risk prevention tools

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37. GIVING TEACHERS BETTER TOOLS TO
TEACH SCIENCE

38. BUILDING A COMPUTER CONTROL
GARDEN WITH TEACHER AND STUDENTS

39. REMOTE STUDENT MENTORING (US TO
ISRAEL) PRESENTED TO PRESIDENT PERES

40. PARENTS, TEACHERS &
VOLUNTEERS LEAD SCIENCE
DAY

41. PARENTS, TEACHERS &
VOLUNTEERS LEAD SCIENCE
DAY
I know what I want to be when I grow up, a
Doctor, and I am making good progress!

42. BRINGING HI-TECH TO BEIT SHEMESH