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17/04/2020 1MOUNESH
INTRODUCTION
• Blepharitis is inflammation or infection of
the eyelid margins .
• Blepharitis is one the most common
ophthalmological complications as well as
one of the most difficult conditions to treat.
17/04/2020 2MOUNESH
BLEPHARITIS
Blepharitis is a common eyelid inflammation
that sometimes is associated with a bacterial
eye infection, symptoms of dry eyes or certain
types of skin conditions such as acne rosacea.
Blepharitis is one of the most frequently observed
conditions among eye care practitioners, yet
remains largely misunderstood.
17/04/2020 3MOUNESH
SLIT-LAMP BIOMICROSCOPY
The slit-lamp biomicroscope is an
important diagnostic instrument for
the examination of the anterior eye
structures as well as the contact lens.
Being able to proficiently use the
instrument is important. It use
critical in the fitting of contact
lenses.
17/04/2020 4MOUNESH
17/04/2020 5MOUNESH
CLASSIFICATION
 ANTERIOR
 POSTERIOR
17/04/2020 6MOUNESH
1. Anterior
• Staphylococcal
• Seborrhoeic
2. Posterior
• Meibomianitis
• Meibomian seborrhoea
Staph
Blepharitis
17/04/2020 7MOUNESH
ANTERIOR BLEPHARITIS
Anterior blepharitis is characterized by
inflammation at the base of the eyelashes .
Patients with anterior blepharitis, compared
to those with posterior blepharitis, are more
likely to be female and younger *
17/04/2020 8MOUNESH
Two variants of anterior blepharitis are
identified: staphylococcal and seborrheic.
In staphylococcal anterior blepharitis,
colonization of the eyelids by staphylococci leads
to formation of fibrinous scales and crust around
the eyelashes.
The seborrheic variant is characterized by
dandruff-like skin changes around the base of the
eyelids, resulting in greasy scales around the
eyelashes.
17/04/2020 9MOUNESH
PATHOPHYSIOLOGY
The pathophysiology of blepharitis is not completely
understood. A role for lid-colonizing staphylococcal
bacteria was first noted in 1946 . Several mechanisms by
which staphylococci may alter meibomian gland
secretion and cause blepharitis are supported by many
studies .
Direct infection of the lids
Evoke reaction to staphylococcal exotoxin
Provoke allergic response to staphylococcal antigens .
It is likely that a combination of these is responsible for
the clinical manifestations of staphylococcal blepharitis.
17/04/2020 10MOUNESH
CLINICAL PRESENTATION
symptoms
burning , grittiness and mild photophobia
with remission and exacerbation is
characteristic .
Symptoms are usually worse in the morning
, although in patients with dry eye they may
increase during the day .
17/04/2020 11MOUNESH
SIGNS
A. Staphylococcal blepharitis
 Hard scales and crusing mainly located around
the bases of the lashes esp. collorette
chronic conjunctival hyperemia with mild
papillary conjunctivitis .
17/04/2020 12MOUNESH
STAPHYLOCOCCAL
BLEPHARITIS
Hyperaemia and telangiectasia of •
anterior lid margin
Scarring and hypertrophy if •
longstanding
Scales around base of lashes •
(collarettes)
Chronic irritation worse in morning•
17/04/2020 13MOUNESH
Cont. Signs of Staphylococcal
blepharitis
Scarring
Notching (tylosis) of the lid margin
Trichiasis (misdirected eyelashes)
Madarosis (loss of lashes) or
Poliosis (loss of pigmentation of
lashes) in sever long standing cases
17/04/2020 14MOUNESH
Cont. Signs of Staphylococcal
blepharitis
17/04/2020 15MOUNESH
secondary changes include :
 stye formation
marginal keratitis and occasionally
phlyctenulosis (Corneal nodules that developed
near the limbus and then spread onto the cornea,
carrying behind them a leash of vessels)
 associated with tear film instability and dry eye
.
17/04/2020 16MOUNESH
The diagnosis of blepharitis is clinical, based on
the patient's history and physical examination
findings. There are no confirmatory diagnostic
tests or laboratory investigations.
The history should include questions about
symptom duration, smoking, allergens, contact
lenses, and use of retinoids which may provoke
or exacerbate symptoms. A history of acne,
rosacea, or eczema should be evaluated .
DIAGNOSIS
17/04/2020 17MOUNESH
17/04/2020 18MOUNESH
EXAMINATION OF THE TEAR FILM
Bubbles, also called frothing, can sometimes be seen in the tear
film, especially along the lid margins. This can indicate
meibomianitis.
17/04/2020 19MOUNESH
17/04/2020 20MOUNESH
The lashes should be examined for abnormalities
such blepharitis. With blepharitis there will be
collarettes found at the base of the lashes.
Plugged
gland
17/04/2020 21MOUNESH
• Burning
• Flaking
• Crusting
• Tearing
• Irritation
• Itching
• redness
• Foreign body
sensation
• Bulbar and
palpebral
hyperemia
17/04/2020 22MOUNESH
TREATMENT FOR BLEPHARITIS
Anterior Blepharitis
• staphylococcal blepharitis
more severe
loss of eyelashes
eyelid cleansing and hygiene
antibiotic ointment for eyelids
Viruses and other types of
bacteria besides
staphylococcus also can cause
anterior blepharitis
• Seborrheic blepharitis
seborrheic dermatitis
Regular cleansing with
eyelid
scrubs and gentle, non-
detergent shampoos
17/04/2020 23MOUNESH
Without treatment :
blepharitis caused by bacteria can cause
long-term effects such as ectropion,
thickened lid margins, dilated and visible
capillaries, trichiasis and entropion.
In cases of trichiasis and entropion, the
cornea may exhibit significant erosion
from eyelashes rubbing against the eye.
17/04/2020 24MOUNESH
Eyelid Hygiene Relieves Blepharitis
Symptoms
 Blepharitis can be difficult to manage because it is
often chronic, meaning that it never warm compress
goes away completely. Your eye doctor may
recommend one or more of these steps involving
good eyelid hygiene and massage:
 Apply a such as a washcloth to the outer eyelids.
 Cleanse the eyelids with a commercial lid scrub or
other
recommended product.
 Gently massage the outer eyelids.
 A warm compress loosens the crust on your eyelids
and eyelashes before you clean them. The warmth
also can loosen any blocked residue in the oil-
secreting meibomian glands in your eyelids
17/04/2020 25MOUNESH
17/04/2020 26MOUNESH

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Blepharitis

  • 2. INTRODUCTION • Blepharitis is inflammation or infection of the eyelid margins . • Blepharitis is one the most common ophthalmological complications as well as one of the most difficult conditions to treat. 17/04/2020 2MOUNESH
  • 3. BLEPHARITIS Blepharitis is a common eyelid inflammation that sometimes is associated with a bacterial eye infection, symptoms of dry eyes or certain types of skin conditions such as acne rosacea. Blepharitis is one of the most frequently observed conditions among eye care practitioners, yet remains largely misunderstood. 17/04/2020 3MOUNESH
  • 4. SLIT-LAMP BIOMICROSCOPY The slit-lamp biomicroscope is an important diagnostic instrument for the examination of the anterior eye structures as well as the contact lens. Being able to proficiently use the instrument is important. It use critical in the fitting of contact lenses. 17/04/2020 4MOUNESH
  • 7. 1. Anterior • Staphylococcal • Seborrhoeic 2. Posterior • Meibomianitis • Meibomian seborrhoea Staph Blepharitis 17/04/2020 7MOUNESH
  • 8. ANTERIOR BLEPHARITIS Anterior blepharitis is characterized by inflammation at the base of the eyelashes . Patients with anterior blepharitis, compared to those with posterior blepharitis, are more likely to be female and younger * 17/04/2020 8MOUNESH
  • 9. Two variants of anterior blepharitis are identified: staphylococcal and seborrheic. In staphylococcal anterior blepharitis, colonization of the eyelids by staphylococci leads to formation of fibrinous scales and crust around the eyelashes. The seborrheic variant is characterized by dandruff-like skin changes around the base of the eyelids, resulting in greasy scales around the eyelashes. 17/04/2020 9MOUNESH
  • 10. PATHOPHYSIOLOGY The pathophysiology of blepharitis is not completely understood. A role for lid-colonizing staphylococcal bacteria was first noted in 1946 . Several mechanisms by which staphylococci may alter meibomian gland secretion and cause blepharitis are supported by many studies . Direct infection of the lids Evoke reaction to staphylococcal exotoxin Provoke allergic response to staphylococcal antigens . It is likely that a combination of these is responsible for the clinical manifestations of staphylococcal blepharitis. 17/04/2020 10MOUNESH
  • 11. CLINICAL PRESENTATION symptoms burning , grittiness and mild photophobia with remission and exacerbation is characteristic . Symptoms are usually worse in the morning , although in patients with dry eye they may increase during the day . 17/04/2020 11MOUNESH
  • 12. SIGNS A. Staphylococcal blepharitis  Hard scales and crusing mainly located around the bases of the lashes esp. collorette chronic conjunctival hyperemia with mild papillary conjunctivitis . 17/04/2020 12MOUNESH
  • 13. STAPHYLOCOCCAL BLEPHARITIS Hyperaemia and telangiectasia of • anterior lid margin Scarring and hypertrophy if • longstanding Scales around base of lashes • (collarettes) Chronic irritation worse in morning• 17/04/2020 13MOUNESH
  • 14. Cont. Signs of Staphylococcal blepharitis Scarring Notching (tylosis) of the lid margin Trichiasis (misdirected eyelashes) Madarosis (loss of lashes) or Poliosis (loss of pigmentation of lashes) in sever long standing cases 17/04/2020 14MOUNESH
  • 15. Cont. Signs of Staphylococcal blepharitis 17/04/2020 15MOUNESH
  • 16. secondary changes include :  stye formation marginal keratitis and occasionally phlyctenulosis (Corneal nodules that developed near the limbus and then spread onto the cornea, carrying behind them a leash of vessels)  associated with tear film instability and dry eye . 17/04/2020 16MOUNESH
  • 17. The diagnosis of blepharitis is clinical, based on the patient's history and physical examination findings. There are no confirmatory diagnostic tests or laboratory investigations. The history should include questions about symptom duration, smoking, allergens, contact lenses, and use of retinoids which may provoke or exacerbate symptoms. A history of acne, rosacea, or eczema should be evaluated . DIAGNOSIS 17/04/2020 17MOUNESH
  • 19. EXAMINATION OF THE TEAR FILM Bubbles, also called frothing, can sometimes be seen in the tear film, especially along the lid margins. This can indicate meibomianitis. 17/04/2020 19MOUNESH
  • 21. The lashes should be examined for abnormalities such blepharitis. With blepharitis there will be collarettes found at the base of the lashes. Plugged gland 17/04/2020 21MOUNESH
  • 22. • Burning • Flaking • Crusting • Tearing • Irritation • Itching • redness • Foreign body sensation • Bulbar and palpebral hyperemia 17/04/2020 22MOUNESH
  • 23. TREATMENT FOR BLEPHARITIS Anterior Blepharitis • staphylococcal blepharitis more severe loss of eyelashes eyelid cleansing and hygiene antibiotic ointment for eyelids Viruses and other types of bacteria besides staphylococcus also can cause anterior blepharitis • Seborrheic blepharitis seborrheic dermatitis Regular cleansing with eyelid scrubs and gentle, non- detergent shampoos 17/04/2020 23MOUNESH
  • 24. Without treatment : blepharitis caused by bacteria can cause long-term effects such as ectropion, thickened lid margins, dilated and visible capillaries, trichiasis and entropion. In cases of trichiasis and entropion, the cornea may exhibit significant erosion from eyelashes rubbing against the eye. 17/04/2020 24MOUNESH
  • 25. Eyelid Hygiene Relieves Blepharitis Symptoms  Blepharitis can be difficult to manage because it is often chronic, meaning that it never warm compress goes away completely. Your eye doctor may recommend one or more of these steps involving good eyelid hygiene and massage:  Apply a such as a washcloth to the outer eyelids.  Cleanse the eyelids with a commercial lid scrub or other recommended product.  Gently massage the outer eyelids.  A warm compress loosens the crust on your eyelids and eyelashes before you clean them. The warmth also can loosen any blocked residue in the oil- secreting meibomian glands in your eyelids 17/04/2020 25MOUNESH