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12/18/2020 5:02:22 AM 1MOUNESH
Relevant anatomy and
physiology
The canal permits fluid to drain out of the eye into
the systemic circulation so a constant intraocular
pressure is maintained.
12/18/2020 5:02:22 AM 2MOUNESH
12/18/2020 5:02:22 AM 3MOUNESH
GLAUCOMA
(ocular hypertension)
Definition:
Glaucoma is a group of
ocular disorders
characterized by
o Increased IOP
o Cupping and
atrophy of the optic
nerve head
o Visual field
changes
12/18/2020 5:02:22 AM 4MOUNESH
12/18/2020 5:02:22 AM 5MOUNESH
CLASSIFICATION
(By the anatomic size of the anterior chamber angle)
Open – Angle Glaucoma ( wide)
Angle – Closure Glaucoma
12/18/2020 5:02:22 AM 6MOUNESH
12/18/2020 5:02:22 AM 7MOUNESH
ETIOLOGY & RISK FACTORS
Age
Heredity
Myopia
Diabetes mellitus
Ocular trauma
Ocular surgery
Topical & peri-ocular corticosteroids
12/18/2020 5:02:22 AM 8MOUNESH
PATHOPHYSIOLOGY
12/18/2020 5:02:22 AM 9MOUNESH
Due to etiological factors
Increased IOP
Compress and damage optic nerve
It fails to carry visual information to the
brain
Results in loss of vision
12/18/2020 5:02:22 AM 10MOUNESH
SIGNS & SYMPTOMS
Eye Pain
Gradual loss of peripheral vision followed by
loss of vision in the end stage
Blurred vision
Rainbow halos around light
Nausea vomiting sometimes, accompanied
by abdominal pain
12/18/2020 5:02:22 AM 11MOUNESH
Redness of the sclera & conjunctiva
Increased IOP
Tunnel Vision
Difficulty to focusing on near or distant
objects
12/18/2020 5:02:22 AM 12MOUNESH
Squinting Or Blinking
Red – Rimmed , Encrusted Or Swollen Lids
Double Vision
Excess Tearing Or Watery Eyes
12/18/2020 5:02:22 AM 13MOUNESH
DIAGNOSTIC EVALUATION
History collection
Physical examination
Tonometry: Determine the intraocular
pressure
12/18/2020 5:02:22 AM 14MOUNESH
Gonioscopy: is using a
goniolens together with a
slit lamp or operating
microscope to view the
iridocorneal angle, or the
anatomical angle formed
between the eye's cornea
and iris
Opthalmoscopy:Visualiza
tion of the retina
12/18/2020 5:02:22 AM 15MOUNESH
Perimetry Test: A
visual field test is an eye
examination that can
detect dysfunction in
central and peripheral
vision
12/18/2020 5:02:22 AM 16MOUNESH
Dilated Eye Exam:
examine the health of the
optic nerve and retina.
Slit-lamp examination:
12/18/2020 5:02:22 AM 17MOUNESH
MEDICAL MANAGEMENT
Antiglaucoma medications
Cholinergies: Decrease formation & increase outflow of
aqeous humor. Widens trabecular meshworks. E.g.
pilocarpine, carbachol.
Anticholinergies: Contracts ciliary muscles, which
facilitatets outflow of aqueous humor. E.g. Ecothiophate
iodide, physostigmine.
Adrenergic agonist: Inhibits aqueos production &
facilitates outflow. E.g. Epinephrine, Divirfrin.
12/18/2020 5:02:22 AM 18MOUNESH
Beta-Adrenergic Antagonists (Sympathometics):
Reduces aquueous humor formation & may increase
outflow.E.g. Tilmolo, Betaxolol.
Carbonic anhydrase inhibitors: Decreases aqueous
production by inhibiting carbonic anhydrase in the ciliary
body. E.g. Acetazolamide, Methozolamide.
Hypersomatic agents: Movement of water from
introcular structures to circulation via plasma osmolarity.
E.g. Glycerine, Mannitol
12/18/2020 5:02:22 AM 19MOUNESH
SURGICAL
MANAGEMENT
12/18/2020 5:02:22 AM 20MOUNESH
Laser procedure
Laser Trabeculoplasty: It is done on an argon laser
equipped slit lamp, using a Goldmann gonioscope lens
mirror. Specifically, argon laser is used to improve
drainage through the eye's trabecular meshwork, from
which the aqueous humour drains.
12/18/2020 5:02:22 AM 21MOUNESH
Argon & krypton
peripheral iridoplasty is a useful procedure to
eliminate appositional angle closure. The laser is
applied at the iris periphery. Heat from laser
creates iris stromal shrinkage and mechanically
pulls away iris tissue from trabecular meshwork.
12/18/2020 5:02:22 AM 22MOUNESH
Laser iridotomy
laser iridotomy is to allow an equalization of pressure
between the anterior (front) and posterior (back) chambers
of the eye by making a hole in the superior peripheral iris.
12/18/2020 5:02:22 AM 23MOUNESH
Viscocanalostomy
• Viscocanalostomy is a non-penetrating procedure
aimed at increasing the outflow facility by creating
significant morphologic changes at the trabecular
meshwork level. It is an effective procedure in
lowering intraocular pressure (IOP) in open-angle
glaucomatous eyes.
12/18/2020 5:02:22 AM 24MOUNESH
Filtering procedures
Trephine: Step by step operative procedure to
correct strabismus (resection of the right internal
rectus muscle) and resection and advancement of
right external rectus muscle.
12/18/2020 5:02:22 AM 25MOUNESH
SCLERECTOMY
• This surgery works by building up new
outflow pathways for the drainage of the
aqueous humor while maintaining the
integrity of the anterior chamber
12/18/2020 5:02:22 AM 26MOUNESH
THERMAL SCLEROSTOMY
12/18/2020 5:02:22 AM 27MOUNESH
TRABECULECTOMY
• Trabeculectomy: This is achieved by making
a small hole in the eye wall (sclera), covered
by a thin trap-door in the sclera.
12/18/2020 5:02:22 AM 28MOUNESH
FILTERING TUBES AND
IMPLANTS
Aqueous shunts or glaucoma drainage devices
(GDD) are artificial filtering devices which
lower the intraocular pressure (IOP) by
draining aqueous humor to the external
subconjunctival space.
12/18/2020 5:02:22 AM 29MOUNESH
CYCLOCRYOTHERAPY
It is a procedure that employs temperatures as low as
-112°F (-80°C) to destroy the ciliary body. Ablation, or
destruction, of part of the ciliary body lowers the IOP
by decreasing the fluid or aqueous humor within the
eye and thus helping to control glaucoma.
12/18/2020 5:02:22 AM 30MOUNESH
CYCLODIALYSIS
• Cyclodialysis is the result of the separation of
the longitudinal ciliary muscle fibers from the
scleral spur, which creates an abnormal
pathway for aqueous humor drainage that may
lead to ocular hypotony. (Spatula)
12/18/2020 5:02:22 AM 31MOUNESH
12/18/2020 5:02:22 AM 32MOUNESH
COMPLICATION
Blindness
Post operative complications
Corneal damage
Haemorrhage
Iritis
Hypotony (Flat anterior chamber)
Cataract formation
Atrophy of the eyeball (phthisis bulbi)
Cystoid macular oedema
12/18/2020 5:02:22 AM 33MOUNESH
PROGNOSIS
There is no cure for glaucoma
Early detection and treatment maximize
preservation of vision
12/18/2020 5:02:22 AM 34MOUNESH
12/18/2020 5:02:22 AM 35MOUNESH

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Glaucoma

  • 2. Relevant anatomy and physiology The canal permits fluid to drain out of the eye into the systemic circulation so a constant intraocular pressure is maintained. 12/18/2020 5:02:22 AM 2MOUNESH
  • 4. GLAUCOMA (ocular hypertension) Definition: Glaucoma is a group of ocular disorders characterized by o Increased IOP o Cupping and atrophy of the optic nerve head o Visual field changes 12/18/2020 5:02:22 AM 4MOUNESH
  • 6. CLASSIFICATION (By the anatomic size of the anterior chamber angle) Open – Angle Glaucoma ( wide) Angle – Closure Glaucoma 12/18/2020 5:02:22 AM 6MOUNESH
  • 8. ETIOLOGY & RISK FACTORS Age Heredity Myopia Diabetes mellitus Ocular trauma Ocular surgery Topical & peri-ocular corticosteroids 12/18/2020 5:02:22 AM 8MOUNESH
  • 10. Due to etiological factors Increased IOP Compress and damage optic nerve It fails to carry visual information to the brain Results in loss of vision 12/18/2020 5:02:22 AM 10MOUNESH
  • 11. SIGNS & SYMPTOMS Eye Pain Gradual loss of peripheral vision followed by loss of vision in the end stage Blurred vision Rainbow halos around light Nausea vomiting sometimes, accompanied by abdominal pain 12/18/2020 5:02:22 AM 11MOUNESH
  • 12. Redness of the sclera & conjunctiva Increased IOP Tunnel Vision Difficulty to focusing on near or distant objects 12/18/2020 5:02:22 AM 12MOUNESH
  • 13. Squinting Or Blinking Red – Rimmed , Encrusted Or Swollen Lids Double Vision Excess Tearing Or Watery Eyes 12/18/2020 5:02:22 AM 13MOUNESH
  • 14. DIAGNOSTIC EVALUATION History collection Physical examination Tonometry: Determine the intraocular pressure 12/18/2020 5:02:22 AM 14MOUNESH
  • 15. Gonioscopy: is using a goniolens together with a slit lamp or operating microscope to view the iridocorneal angle, or the anatomical angle formed between the eye's cornea and iris Opthalmoscopy:Visualiza tion of the retina 12/18/2020 5:02:22 AM 15MOUNESH
  • 16. Perimetry Test: A visual field test is an eye examination that can detect dysfunction in central and peripheral vision 12/18/2020 5:02:22 AM 16MOUNESH
  • 17. Dilated Eye Exam: examine the health of the optic nerve and retina. Slit-lamp examination: 12/18/2020 5:02:22 AM 17MOUNESH
  • 18. MEDICAL MANAGEMENT Antiglaucoma medications Cholinergies: Decrease formation & increase outflow of aqeous humor. Widens trabecular meshworks. E.g. pilocarpine, carbachol. Anticholinergies: Contracts ciliary muscles, which facilitatets outflow of aqueous humor. E.g. Ecothiophate iodide, physostigmine. Adrenergic agonist: Inhibits aqueos production & facilitates outflow. E.g. Epinephrine, Divirfrin. 12/18/2020 5:02:22 AM 18MOUNESH
  • 19. Beta-Adrenergic Antagonists (Sympathometics): Reduces aquueous humor formation & may increase outflow.E.g. Tilmolo, Betaxolol. Carbonic anhydrase inhibitors: Decreases aqueous production by inhibiting carbonic anhydrase in the ciliary body. E.g. Acetazolamide, Methozolamide. Hypersomatic agents: Movement of water from introcular structures to circulation via plasma osmolarity. E.g. Glycerine, Mannitol 12/18/2020 5:02:22 AM 19MOUNESH
  • 21. Laser procedure Laser Trabeculoplasty: It is done on an argon laser equipped slit lamp, using a Goldmann gonioscope lens mirror. Specifically, argon laser is used to improve drainage through the eye's trabecular meshwork, from which the aqueous humour drains. 12/18/2020 5:02:22 AM 21MOUNESH
  • 22. Argon & krypton peripheral iridoplasty is a useful procedure to eliminate appositional angle closure. The laser is applied at the iris periphery. Heat from laser creates iris stromal shrinkage and mechanically pulls away iris tissue from trabecular meshwork. 12/18/2020 5:02:22 AM 22MOUNESH
  • 23. Laser iridotomy laser iridotomy is to allow an equalization of pressure between the anterior (front) and posterior (back) chambers of the eye by making a hole in the superior peripheral iris. 12/18/2020 5:02:22 AM 23MOUNESH
  • 24. Viscocanalostomy • Viscocanalostomy is a non-penetrating procedure aimed at increasing the outflow facility by creating significant morphologic changes at the trabecular meshwork level. It is an effective procedure in lowering intraocular pressure (IOP) in open-angle glaucomatous eyes. 12/18/2020 5:02:22 AM 24MOUNESH
  • 25. Filtering procedures Trephine: Step by step operative procedure to correct strabismus (resection of the right internal rectus muscle) and resection and advancement of right external rectus muscle. 12/18/2020 5:02:22 AM 25MOUNESH
  • 26. SCLERECTOMY • This surgery works by building up new outflow pathways for the drainage of the aqueous humor while maintaining the integrity of the anterior chamber 12/18/2020 5:02:22 AM 26MOUNESH
  • 28. TRABECULECTOMY • Trabeculectomy: This is achieved by making a small hole in the eye wall (sclera), covered by a thin trap-door in the sclera. 12/18/2020 5:02:22 AM 28MOUNESH
  • 29. FILTERING TUBES AND IMPLANTS Aqueous shunts or glaucoma drainage devices (GDD) are artificial filtering devices which lower the intraocular pressure (IOP) by draining aqueous humor to the external subconjunctival space. 12/18/2020 5:02:22 AM 29MOUNESH
  • 30. CYCLOCRYOTHERAPY It is a procedure that employs temperatures as low as -112°F (-80°C) to destroy the ciliary body. Ablation, or destruction, of part of the ciliary body lowers the IOP by decreasing the fluid or aqueous humor within the eye and thus helping to control glaucoma. 12/18/2020 5:02:22 AM 30MOUNESH
  • 31. CYCLODIALYSIS • Cyclodialysis is the result of the separation of the longitudinal ciliary muscle fibers from the scleral spur, which creates an abnormal pathway for aqueous humor drainage that may lead to ocular hypotony. (Spatula) 12/18/2020 5:02:22 AM 31MOUNESH
  • 33. COMPLICATION Blindness Post operative complications Corneal damage Haemorrhage Iritis Hypotony (Flat anterior chamber) Cataract formation Atrophy of the eyeball (phthisis bulbi) Cystoid macular oedema 12/18/2020 5:02:22 AM 33MOUNESH
  • 34. PROGNOSIS There is no cure for glaucoma Early detection and treatment maximize preservation of vision 12/18/2020 5:02:22 AM 34MOUNESH