presented by HAFIZ M WASEEM university of education LAHORE Pakistan i am from mailsi vehari and studied in lahore bsc in science college multan msc from lahore

1. HAFIZ M WASEEM UNIVERSITY
OF EDUCATION LAHORE

2. Table of Contents
Serial # CONTENTS
EOSINOPENIA
Symptoms
Causes
Treatment
Conclusion

3. AN OVERVIEW
• There are number of elements in the circulating tissue called as the
blood.There are three types of Blood Elements:
 RBC’S (Erythrocytes)
 WBC’S (Leukocytes)
 Blood Platelets (Thrombocytes)
The main discussion point is the Eosinophils related disorder.
Our WBC’s are composed of
1.Neutrophils
2.Eosinophils
3.Basophils
The Eosinophils are
little larger than the
neutrophil. The
granules are spherical.
They have three lobed
nuclei.

4. • Now, as our main concern is about eosinophils;
in normal healthy person normal number of eosinophils are
1-3% in the peripheral blood.
Now, in abnormal condition there are two poosibilities:
• Eosinophil level may increase called as eosinophilia,
• It may decreasefrom the normal called as eosinopenia.

5. Eosinopenia
In precised term a
characteristic the decrease in
the eosinophil level of
peripheral blood is called as
the eosinopenia.
It is considered low a number
of less than 50-100
eosinophils per mm3 of
blood..

6. ACTIVITY OF
EOSINOPHILS

7. Symptoms of Eosinopenia
• The reason for having no particular
symptom is because the
eosinopenia is associated with the
low number of cells in the
peripheral blood.
• It can occur together with the
symptoms of other diseases
• Fever
• Infection
• Hives
• Asthma
• Allergic Reactions
• Stroke
• Immunoglobins deficiency
• Auto immune disorders.

8. The most important of the case which I
could never be able to neglect is the
symptom of pandemic COVID-19 also
has the shortage of the Eosinophils.
 AcutePancreatitiss
Acute Upper Gastrointestinal
Bleeding.
 Acute Myocardial
Infarction.
 Cerebrovascular Accident.
 Typhoid Fever.
 Rash .
 Leptospirosis.
 Fever of Unknown Origin
 Inflammation of Unknown
Region.

9. 1.Inflectional Effect:
When there is accumulation of these cells occur in the tissues or the organs where there
is bacterial infection, or the parasite present; these cells become less in the blood flowing in
the periphery of the body. It means the infection whether it is viral or bacterial can induce
eosinopenia.
2.Corticosteroid Drug:
When the high dose of this drug is implemented it can also lead to the eosinopenia
because it decreases the amount of Eosinophils

10. 3.Stress:
Stress is also the factor of the eosinopenia because under stress internal
corticosteroid and epinephrine production lowers the total number of
Eosinophils around.

11. DIAGNOSIS
• The diagnosis of eosinopenia occurs by Absolute eosinophil count.
• Also the Hemogram exhibits the amount of the eosinophils in the
peripheral blood.
• Less than 40 eosinophils per mm 3 of blood and more than
10,000 leukocytes per mm 3blood test, the specificity and the
positive predictive value for bacterial infection is 100%.(Disease
inicator)
• The Eosinopenia severe (less than 10 eosinophils / mm 3 ) is a very
specific marker for sepsis (a potentially fatal syndrome caused by an
excessive immune response to infection) in the emergency
department.

12. TREATMENT
• It is necessary to determine what the cause may be in
order to apply the correct treatment.
• If the cause of eosinopenia were only stress,
medications could be used to lower its levels.

13. • If the cause was the administration of corticosteroids,
this medication could be substituted for another or the
doses could be adjusted and the risk / benefit ratio
evaluated.
• Regarding the cause of infections, the application of
the correct antimicrobial therapy (antibiotics,
antiparasitics) would result in a rapid resolution of the
eosinopenia.

14. Conclusion:
• Although by itself it is not a cause for concern, if it occurs
together with these alterations, the cause should be
evaluated. It can also be used as an indicator for
infections.
• The treatment of eosinopenia goes through establishing
the causes and acting on them.