15. HIstopathology showing homogeneous eosinophilic
deposits lying between the renal pigment epithelium
(RPE and the inner conagenous layer or Bruch
membrane:
16. OCT showing
drusen (arrows): C
initial image: (D
same eye 4 years
after showing an
increase in number
and size of drusen:
(E) drusen with
associated
pigmentary
abnormalities
17.
18.
19.
20.
21.
22.
23.
24. Age-related macular
degeneration without
neovascularization. (A)
Druse and mild
pigmentary changes; b
same eye as [A) 4
years later with
moderate retinal
atrophy and
pigmentary
abnormalities; (C)
geographic atrophy;
(D) late FA of eye in
(C);
25.
26. ; (E) substantial geographic atrophy and pigmentary
abnormalities; (F) OCT showing outer retinal
tubulations
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37. Occult (Type 1)
choroidal
neovascularization. (A)
Specks of blood at the
fovea; (B–D) FA
showing diffuse
hyperfluorescence but
the limits of the
membrane cannot be
defined; (E) OCT
showing a PED with
variable internal
reflectivity and
subretinal fluid
38. Classic (Type 2) subfoveal
choroidal neovascularization.
(A) Colour image showing
grey–green area and small
haemorrhage; (B) early FA
showing ‘lacy’
hyperfluorescent pattern and
an area of hypofluorescence
secondary to the haemorrhage;
(C) late venous phase – more
intense hyperfluorescence with
leakage and staining; (D)
persistent staining at 10
minutes; (E) OCT showing
subretinal hyper-reflective
material (arrow)
