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Anaemia FREE INDIA-Public AwarenessLifecare Centre_Dr.Jyoti Bhaskar
- 2. • Group photo Our Team PRESENTED At GYNAECON 10/10/2015 Our MISSION: SAY No TO ANAEMIA
- 3. DR. JYOTI BHASKAR DR. SHARDA JAIN Dr.Jyoti Aggarwal SOARING HIGH !! THROUGH IRON LIBERATION
- 6. MAGNITUDE • 49.7% of Indian pregnant women suffer from anemia (WHO Global database, 2006) 20 % maternal deaths contributed by anemia • Iron deficiency anemia (IDA) commonest cause of anemia in pregnancy Most Common deficiency state in the world Preventable and correctable cause of anemia. Dr. Sharda Jain – An activist and protagonist of Anaemia Free India – 80% pregnant women are Anaemic
- 7. Every Parent Aspires That There Child will Become another APJ ABDUL KALAM
- 8. HARD FACT HAEMOGLOBIN LEVELS AFFECTS • INTELLIGENCE • PERFORMACE • Diminished concentration • Disturbance in perception • Poor learning ability
- 9. Reduced Performance and Productivity Decreased Work Output Decreased Work Capacity
- 10. Anaemic Mother gives birth to an Anaemic Baby • Irregular Heavy menstruation • Low pre-pregnancy iron stores • LBW babies and preterm delivery
- 11. Hemorrhage 30% Anemia 19% Sepsis 16% Abortion 9% Obst. Lab 10% Toxemia 8% Others 8% CAUSES OF MATERNAL MORTALITY SRS-1998 - Direct cause of 20%of maternal deaths Indirect cause for another 20% of maternal deaths Nothing is more expensive than a missed opportunity! UNCHANGED FOR 5 DECADES
- 12. Anaemia Death In India, over 300 maternal deaths EVERYDAY, about 200 due to anemia: FOGSI Beyond numbers! For every maternal death, there are 30 more who ‘almost died’.
- 13. Definition WHO defines Anemia as •Hb< 12 gm/dl in women •Hb< 13gm/dl in Men •Anemia in pregnancy refer Hb < 11gm/dl.
- 14. MANAGEMENT
- 15. DIET --- IRON AND PROTEINS
- 16. WHO • Anthelminthic medication in pregnant women with anaemia after 12 weeks of pregnancy • Drug of choice is Mebendazole 100mg BD for 3 days OR Albendazole 400mg
- 17. FERROUS SULPHATE FERROUS GLUCOMATE FERROUS FUMARATE Ferrous Succinate
- 18. PARENTERAL IRON THERAPY INDICATIONS • Non compliance with, or intolerance to, oral iron therapy • Proven malabsorption • No Hemoglobinopathy • Advanced gestation/post partum with moderate to severe anemia
- 19. FORMULATIONS • Low molecular weight Iron Dextran • Iron Sucrose • Ferric Carboxymaltose
- 20. Problems With Existing Parenteral Iron Preparations • The main disadvantage of Iron sucrose is the need for multiple infusions as the maximum weekly dose should not exceed 600 mg (200 mg IV, 1-3 times/week) • Risk of anaphylaxis and allergic reactions • Requirement of test dose administration Cancado RD et al. Rev Bras Hematol Hemoter. 2011; 33(6): 461–469.
- 21. NEWER PREPARATIONS Iron III carboxymaltose (ferric hydroxide carbohydrate complex) • Controlled delivery of iron within cells of reticuloendothelial system (primarily bone marrow) • Subsequent delivery to iron binding proteins ferritin and transferrin. • Rapid incorporation into RBCS
- 22. Dosage • Single intravenous dose of 1000 mg over 15 minutes (maximum 15 mg/kg by injection or 20 mg/kg by infusion) • Dilution: • 500mg ferric carboxymaltose in 100mL sodium chloride 0.9%. • 1000mg ferric carboxymaltose in 250mL sodium chloride 0.9%
- 23. • Flush with 50mL sodium chloride 0.9% before and after iron infusion to minimise risk of extravasation. • Maximum of 1000mg that can be given in one sitting. • No test dose required
- 24. Indications Were Parenteral iron is Indicated: • Adolescents and All Women • Pregnant women in 2nd – 3rd trimester • Post-Partum Women • Before Surgeries
- 25. Take Home Message • We Need to Build an Anaemia free India • Be Obsessed – Detection and Treatment • Switch Over Early – to Parenteral Iron • FCM – is Safe, Patient Friendly and Effective
- 26. Iron strengthens! Gold glittersSilver shines But…
- 27. ISO 14001:2004 (EMS) ISO 9001:2008 PLINE-9650588339/22414049 HELPLINE-9599044257 HELPLINE-9910081484 ISO 9001:2008 HELPLINE 9599044357 …..Caring hearts, healing hands