Reaction of cyclopropane and cyclobutane , pharmaceutical organic chemistry sem- 3 B pharmacy second year

1. REACTION OF
CYCLOPROPANE &
CYCLOBUTANE
NAME : KRISHNA UPADHYAY
ROLL NO.: 264

2. CYCLOPROPANE & CYCLOBUTANE UNDERGOES TWO
TYPES OF REACTIONS:
(A). SUBSTITUTION REACTION
(B). ADDITION REACTION ( RING OPENING
REACTION)

3. (A).SUBSTITUTI
ON REACTION
SUBSTITUTION
WITH Cl2 & Br2
Cycloalkanes
reacts with Cl2 &
Br2 in the
presence of UV
light to give
substitution
products.

4. (B).ADDITIO
N REACTION
(1)Addition of Cl2
& Br2
Cyclopropane Reacts
with Cl2 & Br2 in Dark
to form addition
products. CCl4
is used as a Solvent.
Cyclobutane and
higher members
don't give this

5. (2) Addition of HBr & HI
Cyclopropane reacts with concentrated HBr and HI to
yield 1-bromopropane and 1-iodopropane respectively...
Cyclobutane and higher members do not give this
reaction.

6. (3).Addition of
Hydrogen
Cyclopropane &
cyclobutane reacts with
Hydrogen in the presence
of Ni catalyst to give
propane & n-butane
respectively.
Higher temperature is
required for cyclobutane

7. THANK
YOU