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Third Quarter
Health
An abnormal condition affecting the body of an
organism
Often construed to be a medical condition associated
with specific signs and symptoms
May be caused by factors originally from an external
source such as infectious diseases or internal
dysfunctions such as autoimmune diseases
Any condition that causes pain, dysfunction, distress,
social problems, or death to the person affected
Physical injuries or disabilities are not
classified as disease
There can be several causes for disease,
including infection by a pathogen, genetics
(as in many cancers or deficiencies),
noninfectious environmental causes, or
inappropriate immune responses
The successful colonization of a host by a
microorganism
Can lead to disease, which causes signs and
symptoms resulting in a deviation from the
normal structure or functioning of the host
Microorganisms that can cause disease are
known as pathogens
Signs are objective and measurable, and can be
directly observed by a clinician.
Vital signs, which are used to measure the body’s
basic functions, include:
Body temperature (normally 37 °C [98.6 °F])
Heart rate (normally 60–100 beats per minute)
Breathing rate (normally 12–18 breaths per minute)
Blood pressure (normally between 90/60 and 120/80
mm Hg)
Symptoms of disease are subjective.
They are felt or experienced by the patient, but cannot be
clinically confirmed or objectively measured.
Examples of symptoms include nausea, loss of appetite, and
pain. Such symptoms are important to consider when
diagnosing disease, but they are subject to memory bias and
are difficult to measure precisely.
Some clinicians attempt to quantify symptoms by asking
patients to assign a numerical value to their symptoms.
A specific group of signs and symptoms
characteristic of a particular disease
Many syndromes are named using a
nomenclature based on signs and
symptoms or the location of the disease
Morbidity - the number of cases of a disease
Mortality - the number of deaths due to a disease
Communicable - capable of being spread from person
to person through either direct or indirect mechanisms
Non-communicable infectious disease - not spread
from one person to another (e.g. tetanus)
Non-infectious diseases - not caused by pathogens
(e.g. Down syndrome)
Iatrogenic diseases - diseases that
are contracted as the result of a
medical procedure are known as
Zoonotic diseases - not transmitted
between humans directly but can be
transmitted from animals to humans
Third Quarter
Health
The onset of contagious disease
wherein the virus multiplies until it
affects the body’s defenses
The period when infection and the first
signs and symptoms associated with a
disease appear
During this stage, a sick person may actually spread
the disease-causing microorganisms without knowing
because this is symptom-less stage where microbes
can multiply inside the body and also spread to other
people
The length of this period is dependent on the kind
of microorganism that invades the person and his/her
immune system
For example, the incubation period of chickenpox is
14-16 days and COVID-19 for 5-14 days
During this stage, although the person does not
feel weak, sick, or may not appear sick, the
virus has become stronger than the body’s
defenses
The illness may be spread to other people
This is a short stage of disease development
where a person begins to feel that they are
getting sick
The signs and symptoms during this
stage typically result from activation
of the immune system, such as
fever, pain, soreness, swelling, or
inflammation.
The illness has developed
In case of flu, fever, aches, and pains,
and other symptoms are present
This is the stage where a person feels
the typical signs and symptoms
associated with the disease
This is also the stage where the person
can most easily transmit a
communicable disease to another
person
The peak of illness intensity is known
as acme point
This is the stage of disease development
where the immune system begins to bring
microbial replication under control which
leads to the lessening of the signs and
symptoms associated with the disease
Damaged tissues begin to repair, and
pathogen numbers decrease
This is the final stage of the disease
process where the microbial replication is
fully stopped and the person returns to the
pre-illness stage
Although depending on the disease, the
person may not proceed to this stage and
may die from their disease or be disabled
The progression of an infectious disease can be divided into five periods, which are related
to the number of pathogen particles (red) and the severity of signs and symptoms (blue).
https://courses.lumenlearning.com/microbio
logy/chapter/characteristics-of-infectious-
disease/#:~:text=The%20five%20periods%
20of%20disease,into%20the%20host%20(p
atient).

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Stages of Infection

  • 2. An abnormal condition affecting the body of an organism Often construed to be a medical condition associated with specific signs and symptoms May be caused by factors originally from an external source such as infectious diseases or internal dysfunctions such as autoimmune diseases Any condition that causes pain, dysfunction, distress, social problems, or death to the person affected
  • 3. Physical injuries or disabilities are not classified as disease There can be several causes for disease, including infection by a pathogen, genetics (as in many cancers or deficiencies), noninfectious environmental causes, or inappropriate immune responses
  • 4. The successful colonization of a host by a microorganism Can lead to disease, which causes signs and symptoms resulting in a deviation from the normal structure or functioning of the host Microorganisms that can cause disease are known as pathogens
  • 5. Signs are objective and measurable, and can be directly observed by a clinician. Vital signs, which are used to measure the body’s basic functions, include: Body temperature (normally 37 °C [98.6 °F]) Heart rate (normally 60–100 beats per minute) Breathing rate (normally 12–18 breaths per minute) Blood pressure (normally between 90/60 and 120/80 mm Hg)
  • 6. Symptoms of disease are subjective. They are felt or experienced by the patient, but cannot be clinically confirmed or objectively measured. Examples of symptoms include nausea, loss of appetite, and pain. Such symptoms are important to consider when diagnosing disease, but they are subject to memory bias and are difficult to measure precisely. Some clinicians attempt to quantify symptoms by asking patients to assign a numerical value to their symptoms.
  • 7. A specific group of signs and symptoms characteristic of a particular disease Many syndromes are named using a nomenclature based on signs and symptoms or the location of the disease
  • 8.
  • 9. Morbidity - the number of cases of a disease Mortality - the number of deaths due to a disease Communicable - capable of being spread from person to person through either direct or indirect mechanisms Non-communicable infectious disease - not spread from one person to another (e.g. tetanus) Non-infectious diseases - not caused by pathogens (e.g. Down syndrome)
  • 10. Iatrogenic diseases - diseases that are contracted as the result of a medical procedure are known as Zoonotic diseases - not transmitted between humans directly but can be transmitted from animals to humans
  • 12.
  • 13. The onset of contagious disease wherein the virus multiplies until it affects the body’s defenses The period when infection and the first signs and symptoms associated with a disease appear
  • 14. During this stage, a sick person may actually spread the disease-causing microorganisms without knowing because this is symptom-less stage where microbes can multiply inside the body and also spread to other people The length of this period is dependent on the kind of microorganism that invades the person and his/her immune system For example, the incubation period of chickenpox is 14-16 days and COVID-19 for 5-14 days
  • 15.
  • 16. During this stage, although the person does not feel weak, sick, or may not appear sick, the virus has become stronger than the body’s defenses The illness may be spread to other people This is a short stage of disease development where a person begins to feel that they are getting sick
  • 17. The signs and symptoms during this stage typically result from activation of the immune system, such as fever, pain, soreness, swelling, or inflammation.
  • 18.
  • 19. The illness has developed In case of flu, fever, aches, and pains, and other symptoms are present This is the stage where a person feels the typical signs and symptoms associated with the disease
  • 20. This is also the stage where the person can most easily transmit a communicable disease to another person The peak of illness intensity is known as acme point
  • 21.
  • 22. This is the stage of disease development where the immune system begins to bring microbial replication under control which leads to the lessening of the signs and symptoms associated with the disease Damaged tissues begin to repair, and pathogen numbers decrease
  • 23.
  • 24. This is the final stage of the disease process where the microbial replication is fully stopped and the person returns to the pre-illness stage Although depending on the disease, the person may not proceed to this stage and may die from their disease or be disabled
  • 25. The progression of an infectious disease can be divided into five periods, which are related to the number of pathogen particles (red) and the severity of signs and symptoms (blue).