NIMH/DAR Research Priorities and Funding Opportunities
1. NIMH/DAR
Research Priorities and
Funding Opportunities
Christopher Gordon, Ph.D.
Branch Chief,
NIMH Division of AIDS Research
Johns Hopkins CFAR
November 5, 2014
3. Selected NIMH HIV Research Priorities
Targets Funding Opps
Adherence to ART and PrEP PA-14-126
Steps in HIV care continuum PA-14-132
Approaches
Social determinants and structural interventions PA-14-133
Addressing stigma and health PA-13-248
Mental health and syndemic factors Stay tuned
Basic behavioral and social science PA-14-127
Implementation science PA-14-131
Populations
Key populations evidencing disparities Throughout
4. Adherence to ART and PrEP
NIMH PA-14-126
Improve adherence
monitoring
Novel approaches/technologies for:
-- Timely detection of non-adherence
-- Triaging those in need to intervention
-- Empower patients via real-time feedback loops
Test novel interventions
to improve PrEP and
ART outcomes
-- Technology-assisted approaches
-- Targeting syndemic factors (e.g. depression)
-- Structural/social determinants approaches
(e.g. microeconomic, food security, anti-stigma)
Wisepill
Haberer 2010 AIDS Behav
CBT-AD
Safren 2009 Health Psy
NIMH Contact:
Dr. Michael Stirratt
5. Improving the HIV Care Continuum
NIMH PA-14-130
Study pathways through the
care continuum
-- longitudinal studies
-- disparities populations
Identify determinants and
evaluate approaches to
strengthen…
-- HIV testing (inc. home-testing)
-- Linkage to care
-- Retention in care
Requires research teams to be academic & DoH partnerships.
NIMH Contact:
Dr. Christopher Gordon
Wel-Tel Retain Intervention
Van der Kop + Lester 2013 BMJ Open
Determinants of Care Engagement
Mugavero 2011 CID
6. Social Determinants/Structural Interventions
NIMH PA-14-133
Target areas include… -- Stigma and discrimination -- Social violence
-- Economic factors -- Legal factors
Emphasis on… -- mechanisms by which social determinants shape
prevention and treatment
-- informing structural interventions to ameliorate
these processes and improve outcomes
Sociocultural
Community
Interpersonal
Individual
NIMH Contact:
Dr. Cynthia Grossman
Socio-Ecologic Perspectives
Food Insecurity / Income Generation
Weiser 2011 Am J Clin Nutr
Tsai 2013 PLoS Med
7. Implementation Science and Translational Research
NIMH PA-14-129/131
Key Highlights
Program Officer: Christopher Gordon
Mechanism(s): R01 (131) R21 (129)
Objectives and
Scope
Maximize the public
health impact of
available
interventions
- Deliver interventions efficiently and effectively
- Transfer from one setting/population others
- Better-informed public health decisions
Projects include, but
are not limited to:
- Dissemination Research
- Research Syntheses
- Cost-effectiveness
- Health Systems
- Comparative Effectiveness
- Policy Analysis
8. NIMH Division of AIDS Research –
Contact Information
Susannah Allison, Ph.D. allisonsu@mail.nih.gov
Pim Brouwers Ph.D. ebrouwer@mail.nih.gov
Deborah Colosi, Ph.D. Deborah.colosi@nih.gov
Rebecca DelCarmen-Wiggins, Ph.D. rdelcarm@mail.nih.gov
Christopher Gordon, Ph.D. cgordon1@mail.nih.gov
Cynthia Grossman, Ph.D. grossmanc@mail.nih.gov
Jeymohan Joseph, Ph.D. jjeymoha@mail.nih.gov
Willo Pequegnat, Ph.D. wpequegn@mail.nih.gov
Dianne Rausch, Ph.D. drausch@mail.nih.gov
Michael Stirratt, Ph.D. stirrattm@mail.nih.gov
David Stoff, Ph.D. dstoff@mail.nih.gov
5601 Fishers Lane
Rockville, MD 20852
THANKS!
Editor's Notes
Biomedical advances alone cannot stop the HIV epidemic
Their real-world impact stands on a foundation of behavioral actions and care access.
This is why the current name of the game in HIV is combination prevention.
Inc. social justice and human rights approaches that provide dignity, equity, and access to care for all.
TARGETS – APPROACHES – POPULATIONS
TARGETS
NIMH = heavy focus on behavioral aspects of biomedical prevention
APPROACHES
increasing focus on social and structural interventions, to complement our many individual-level ones
KEY POPS
MSM, MSM of color, transgender, youth, and women, including work globally
